Attenuated processing of proglucagon and glucagon-like peptide-1 in carboxypeptidase E-deficient mice

Journal of Endocrinology

Volumn 169, Issue 3, 2001, Pages 595-602

  Friis Hansen, L ^a   Lacourse, K A ^a   Samuelson, L C ^a   Holst, J J ^a  

^a University of Copenhagen   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYPEPTIDASE H; FAT; FURIN; GLUCAGON LIKE PEPTIDE 1; PEPTIDE HORMONE; PROGLUCAGON;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; ENDOCRINE DISEASE; INTESTINE; MATURATION; MOUSE; NONHUMAN; OBESITY; PANCREAS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PROCESSING;

ANIMALS; CARBOXYPEPTIDASE H; CARBOXYPEPTIDASES; CHROMATOGRAPHY, GEL; DIABETES MELLITUS, EXPERIMENTAL; FURIN; GLUCAGON; GLUCAGON-LIKE PEPTIDE 1; INTESTINES; MICE; MICE, MUTANT STRAINS; OBESITY; PANCREAS; PEPTIDE FRAGMENTS; PROGLUCAGON; PROTEIN PRECURSORS; SUBTILISINS; TISSUE EXTRACTS;

EID: 0034965257     PISSN: 00220795     EISSN: None     Source Type: Journal    
DOI: 10.1677/joe.0.1690595     Document Type: Article

References (31)

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11. A simple salting out procedure for extracting DNA from human nucleated cells
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14. Proglucagon products in plasma of non-insulin dependent diabetics and non-diabetic controls in the fasting state and following oral glucose and intravenous arginine
15. Biological effects and metabolic rates of glucagonlike peptide-1 7-36 amide and glucagonlike peptide-1 7-37 in healthy subjects are indistinguishable
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17. fat mice
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26. fat mice are defective in carboxypeptidase E and proinsulin processing
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31. Internal cleavage of the inhibitory 7B2 carboxyl-terminal peptide by PC2: A potential mechanism for its inactivation