Can oral contraceptive steroids influence the elimination of nifedipine and its primary pyridine metabolite in humans?

European Journal of Clinical Pharmacology

Volumn 54, Issue 9-10, 1998, Pages 729-734

  Balogh, A ^a   Gessinger, S ^a   Svarovsky, U ^a   Hippius, M ^a   Mellinger, U ^b   Klinger, G ^a   Hoffmann, A ^a   Oettel, M ^b  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^b BAYER PHARMA AG   (Germany)

Author keywords

Nifedipine; Oral contraceptives; Pharmacokinetics

Indexed keywords

DIENOGEST; ETHINYLESTRADIOL; LEVONORGESTREL; NIFEDIPINE;

ADULT; ARTICLE; DOSE RESPONSE; DRUG ELIMINATION; DRUG METABOLISM; DRUG PROTEIN BINDING; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN EXPERIMENT; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL;

BIOLOGY; CLINICAL RESEARCH; CLINICAL TRIALS; CONTRACEPTION; CONTRACEPTIVE AGENTS; CONTRACEPTIVE METHODS--PHARMACODYNAMICS; DEVELOPED COUNTRIES; EUROPE; FAMILY PLANNING; GERMANY; METABOLIC EFFECTS--WOMEN; ORAL CONTRACEPTIVES, COMBINED--PHARMACODYNAMICS; ORAL CONTRACEPTIVES--PHARMACODYNAMICS; PHYSIOLOGY; RESEARCH METHODOLOGY; RESEARCH REPORT; WESTERN EUROPE; WOMEN;

ADULT; AREA UNDER CURVE; CALCIUM CHANNEL BLOCKERS; CONTRACEPTIVE AGENTS, FEMALE; CONTRACEPTIVES, ORAL, HORMONAL; CYTOCHROME P-450 ENZYME SYSTEM; DRUG INTERACTIONS; ESTRADIOL CONGENERS; ETHINYL ESTRADIOL; FEMALE; HALF-LIFE; HUMANS; LEVONORGESTREL; MIXED FUNCTION OXYGENASES; NANDROLONE; NIFEDIPINE; PYRIDINES;

EID: 0032411566     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002280050543     Document Type: Article

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