Evaluation of the Intelisite capsule to deliver theophylline and frusemide tablets to the small intestine and colon

European Journal of Pharmaceutical Sciences

Volumn 13, Issue 4, 2001, Pages 375-384

  Clear, Nicola J ^a   Milton, Ashley ^a   Humphrey, Michael ^a   Henry, Brian T ^a   Wulff, Maria ^a   Nichols, Don J ^a   Anziano, Richard J ^b   Wilding, Ian ^c  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

^b PFIZER INC   (United States)

^c PHARMACEUTICAL PROFILES LTD   (United Kingdom)

Author keywords

Frusemide; Intestinal and colonic drug absorption; Non invasive regional drug delivery; Theophylline

Indexed keywords

ABSORPTION; BIOMARKERS; HEALTH; MIXING; WATER;

PHARMACOKINETIC PARAMETERS;

DRUG PRODUCTS;

FUROSEMIDE; PENTETATE TECHNETIUM TC 99M; THEOPHYLLINE;

ADULT; ARTICLE; CLINICAL TRIAL; COLON; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DISSOLUTION; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG CAPSULE; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG SOLUBILITY; GAMMA SCINTIGRAPHY; GASTROINTESTINAL TRANSIT; HUMAN; HUMAN EXPERIMENT; INTESTINE ABSORPTION; MALE; NORMAL HUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SMALL INTESTINE; TABLET; VOLUNTEER;

ADULT; AREA UNDER CURVE; CAPSULES; COLON; CROSS-OVER STUDIES; DIURETICS; FUROSEMIDE; HUMANS; INTESTINAL ABSORPTION; INTESTINE, SMALL; MALE; PHOSPHODIESTERASE INHIBITORS; TABLETS; THEOPHYLLINE;

EID: 0034959307     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0928-0987(01)00134-8     Document Type: Article

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