Mitochondria transfection by oligonucleotides containing a signal peptide and vectorized by cationic liposomes

Antisense and Nucleic Acid Drug Development

Volumn 11, Issue 3, 2001, Pages 175-180

  Geromel, V ^a   Cao, A ^b   Briane, D ^b   Vassy, J ^c   Rotig, A ^a   Rustin, P ^a   Coudert, R ^b,d   Rigaut, J P ^c   Munnich, A ^a   Taillandier, E ^b  

^a HÔPITAL NECKER ENFANTS MALADES   (France)

^b UNIVERSITÉ PARIS 13   (France)

^c SAINT LOUIS HOSPITAL   (France)

^d UNIVERSITÉ DE TOURS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

LIPOSOME; OLIGONUCLEOTIDE; SIGNAL PEPTIDE;

ARTICLE; CELL GROWTH; DISORDERS OF MITOCHONDRIAL FUNCTIONS; FIBROBLAST; FLUORESCENCE; GENE THERAPY; GENE TRANSFER; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

EID: 0034959104     PISSN: 10872906     EISSN: None     Source Type: Journal    
DOI: 10.1089/108729001300338708     Document Type: Article

References (27)

1. Efficient gene transfer into mammalian primary endocrine cells with lipopolyamine-coated DNA
2. Improve biological activity of antisense oligonucleotides conjugated to a fusogenic peptide
3. Fate and expression of the deleted mitochondrial DNA differ between human heteroplasmic skin fibroblast and Epstein-Barr virus-transformed lymphocyte cultures
4. A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: Polyethylenimine
5. Delivery and pathway in MCF7 cells of DNA vectorized by cationic liposomes derived from cholesterol
6. Peptide nucleic acid delivery to human mitochondria
7. Non-viral approaches to gene therapy
8. Lipofection: A highly efficient, lipid-mediated DNA-transfection procedure
9. Endothelial cell transfection with cationic liposomes and herpes simplex-thymine kinase mediated killing
10. A novel cationic liposome reagent for efficiency transfection of mammalian cells
11. Liposome-mediated DNA vaccination
12. Correction of ion transport defect in cystic fibrosis transgenic mice by gene therapy
13. Localization of mitochondria in living cells with rhodamine-123
14. Intracellular distribution of oligonucleotides delivered by cationic liposomes: Light and electron microscopy study
15. Detailed analysis of structures and formation of cationic lipids for efficient gene transfer to the lung
16. Lipid vector systems for gene transfer
17. Phosphorothioate oligodeoxyribonucleotides dissociate from cationic lipids before entering the nucleus
18. Immunotherapy of malignancy by in vivo gene transfer in tumors
19. Mitochondrial import receptors for precursor proteins
20. Temporary ex-vivo inhibition of the expression of the human oncogene HER2(NEU) by a triple-helix-forming oligonucleotide
21. A novel cationic amphiphile for transfection of mammalian cells
22. Processing of artificial peptide-DNA conjugates by the mitochondrial intermediate peptidase (MIP)
23. Transfection of mitochondria: Strategy towards a gene therapy of mitochondrial DNA diseases
24. Selective inhibition of mutant mitochondrial DNA replication in vitro by peptide nucleic acids
25. Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection
26. Mechanism of oligonucleotide release from cationic liposomes