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Volumn 16, Issue 2, 2001, Pages 107-112

Inhibition of chitin synthetase from Saccharomyces cerevisiae by a new UDP-GlcNAc analogue

Author keywords

Azasugar nucleotide; Chitin synthetase; Glycosyltransferase; Inhibition; Transition state analogue; UDP GlcNAc analogue

Indexed keywords

ANTIFUNGAL AGENT; CHITIN SYNTHASE; CHITIN SYNTHASE INHIBITOR; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE N ACETYLGLUCOSAMINE;

EID: 0034958316     PISSN: 87555093     EISSN: None     Source Type: Journal    
DOI: 10.1080/14756360109162360     Document Type: Article
Times cited : (14)

References (31)
  • 18
    • 0041184072 scopus 로고    scopus 로고
    • Iminosugars as Glycosidase inhibitors: Nojirimycin and Beyond, (Stütz, A.E. Ed.), Wiley-VCH.
    • (1999) , pp. 68-92
    • La Ferla, B.1    Nicotra, F.2
  • 20
    • 85037401825 scopus 로고    scopus 로고
    • Abstract
  • 30
    • 85037406464 scopus 로고    scopus 로고
    • 3 CFU/mL. Each assay was performed with a duplicate series of drug dilutions. In brief, the assays were done in RPMI 1640 medium buffered to pH 7.0 with MOPS buffer, Cryptococcus neoformans and Aspergillus fumigatus were tested in the same assay, except that incubations were for 72 h. The dermatophytes T. mentagrophytes and M. canis were incubated at 30 °C for 7 days. The MIC concentration of the drug causing 80% inhibition of fungal growth in comparison with untreated controls


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.