Fas/FasL mediated apoptosis of thyrocytes in Graves' disease

Clinical and Experimental Immunology

Volumn 124, Issue 2, 2001, Pages 197-207

  Sera, N ^a   Kawakami, A ^a   Nakashima, T ^a   Nakamura, H ^a   Imaizumi, M ^a   Koji, T ^a   Abe, Y ^a   Usa, T ^a   Tominaga, T ^a   Ejima, E ^a   Ashizawa, K ^a   Yokoyama, N ^a   Ishikawa, N ^b   Ito, K ^b   Eguchi, K ^a,c  

^a NAGASAKI UNIVERSITY   (Japan)

^b ITO HOSPITAL   (Japan)

^c NAGASAKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Fas mediated apoptosis; Graves' disease; IL 1 ; T cells; Thyrocytes

Indexed keywords

CYCLINE; FAS ANTIGEN; FAS LIGAND; IMMUNOGLOBULIN M ANTIBODY; INTERLEUKIN 1BETA; MONOCLONAL ANTIBODY;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; GRAVES DISEASE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; T LYMPHOCYTE ACTIVATION; THYROID CELL; TISSUE DISTRIBUTION;

ANTIGENS, CD95; APOPTOSIS; DOWN-REGULATION; FAS LIGAND PROTEIN; GRAVES DISEASE; HUMANS; IN SITU NICK-END LABELING; INTERLEUKIN-1; LEUKOCYTES, MONONUCLEAR; MEMBRANE GLYCOPROTEINS; PROLIFERATING CELL NUCLEAR ANTIGEN; T-LYMPHOCYTES; THYROID GLAND;

EID: 0034955121     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.2001.01476.x     Document Type: Article

References (31)

1. The Fas death factor
2. Apoptotic pathways: The roads to ruin
3. Cell suicide for beginners
4. Chronic autoimmune thyroiditis
5. Autoimmune thyroid disease: Further developments in our understanding
6. Apoptosis in thyroid tissue from patients with Hashimoto's thyroiditis
7. Apoptosis in autoimmune and non-autoimmune thyroid disease
8. Potential involvement of Fas and its ligand in the pathogenesis of Hashimoto's thyroiditis
9. Analysis of apoptosis in relation to tissue destruction associated with Hashimoto's autoimmune thyroiditis
10. Fas/Fas ligand up-regulation and Bcl-2 may be significant in the pathogenesis of Hashimoto's thyroiditis
11. Fas/Fas ligand-driven T cell apoptosis as a consequence of ineffective thyroid immunoprivilege in Hashimoto's thyroiditis
12. Gene therapy of experimental autoimmune-thyroiditis by in vivo administration of plasmid DNA coding for Fas ligand
13. Thyroid-stimulating hormone inhibits Fas antigen-mediated apoptosis of human thyrocytes in vitro
14. Modulation of Fas-mediated apoptosis of human thyroid epithelial cells by IgG from patients with Graves' disease (GD) and idiopathic myxedema
15. Graves-Basedow disease Goiter: Model of Bax-Bcl-2 regulated apoptosis
16. Functional Fas ligand expression in thyrocytes from patients with Graves' disease
17. Lack of B7-1/BB1 and B7-2/B7 expression on thyrocytes of patients with Graves' disease. Delivery of costimulatory signals from bystander professional antigen-presenting cells
18. Fas and Fas ligand interaction is necessary for human osteoblast apoptosis
19. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
20. Fas/APO-1/CD95 system as a mediator of granulosa cell apoptosis in ovarian follicle atresia
21. Immunohistochemical localization of Fas antigen paraffin sections with rabbit antibodies against human synthetic Fas peptides
22. Apoptosis in labial salivary glands from Sjögren's syndrome (SS) patients: Comparison with human T lymphotropic virus-I (HTLV-I) -serogegative and -seropositive SS patients
23. Thyroiditis and hepatitis: Fas on the road to disease
24. Apoptosis in the rheumatic diseases
25. Fas-FasL interactions: A common pathogenetic mechanism in organ-specific autoimmunity
26. Role of apoptosis of thyrocytes in a rat model of goiter; a possible involvement of fas system
27. Expression of perforin and granzymes in vivo: Potential diagnostic markers for activated cytotoxic cells
28. Cytotxic lymphocytes require granzyme B for the rapid induction of DNA fgramentation and apoptosis in allogenic target cells
29. Induction of apoptosis by apo-2 ligand, a new member of the tumor necrosis factor cytokine family
30. TRAIL death pathway expression and induction in thyroid follicular cells
31. Interleukin-1 production and action in thyroid tissue