'Glyco-Epitope' assignments for the selectins: Advances enabled by the neoglycolipid (NGL) technology in conjunction with synthetic carbohydrate chemistry

Advances in Experimental Medicine and Biology

Volumn 491, Issue , 2001, Pages 65-78

  Feizi, T ^a  

^a IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOHYDRATE; CARBOHYDRATE BINDING PROTEIN; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; EPITOPE; GLYCOLIPID; GLYCOPROTEIN; L SELECTIN; LIGAND; N ACETYLGLUCOSAMINE; OLIGOSACCHARIDE; SELECTIN; STREPTAVIDIN; SULFATE;

ACETYLATION; AMINO ACID SEQUENCE; BINDING AFFINITY; BIOSYNTHESIS; BIOTINYLATION; BONE MARROW CELL; CARBOHYDRATE ANALYSIS; CELL INTERACTION; CONFERENCE PAPER; DENSITY; IONIZATION; KIDNEY; LEUKOCYTE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN ISOLATION; PROTEIN MODIFICATION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; RECEPTOR BINDING; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS;

MURINAE;

EID: 0034951259     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4615-1267-7_5     Document Type: Conference Paper

References (71)

1. Selectins
2. Carbohydrate ligands of the LEC cell adhesion molecules
3. Marker of peripheral blood granulocytes and monocytes of man recognized by two monoclonal antibodies VEP8 and VEP9 involves the trisaccharide 3-fucosyl-N-acetyllactosamine
4. Species differences in the expression of carbohydrate differentiation antigens on mammalian blood cells revealed by immunofluorescence with monoclonal antibodies
5. Demonstration by monoclonal antibodies that carbohydrate structures of glycoproteins and glycolipids are onco-developmental antigens
6. C-type lectins and sialyl Lewis X oligosaccharides. Versatile roles in cell-cell interaction
7. Leukocyte trafficking mediated by selectin-carbohydrate interactions
8. Leukocyte adhesion: Two selectins converge on sulphate
9. Carbohydrate recognition systems: Functional triads in cell-cell interactions
10. Neoglycolipids: Probes of oligosaccharide structure, antigenicity and function
11. Mass spectrometry in carbohydrate recognition studies
12. Novel approach to the study of the antigenicities and receptor functions of carbohydrate chains of glycoproteins
13. Neoglycolipids: Probes in structure/function assignments to oligosaccharides
14. Two families of murine carbohydrate ligands for E-selectin
15. High-sensitivity structural analyses of oligosaccharide probes (neoglycolipids) by liquid-secondary-ion mass spectrometry
16. Optimal procedure for combined high-performance thin-layer chromatography/high-sensitivity liquid secondary ion mass spectrometry
17. Novel sulfated ligands for the cell adhesion molecule E-selectin revealed by the neoglycolipid technology among O-linked oligosaccharides on an ovarian cystadenoma glycoprotein
18. Characterization of a novel pyruvylated carbohydrate unit implicated in the cell aggregation of the marine sponge Microciona prolifera
19. Nonreductive release of O-linked oligosaccharides from mucin glycoproteins for structure/function assignments as neoglycolipids: Application in the detection of novel ligands for E-selectin
20. Brain contains HNK-1 immunoreactive O-glycans of the sulfoglucuronyl lactosamine series that terminate in 2-linked or 2,6-linked hexose (mannose)
21. High prevalence of 2-mono- and 2,6-di-substituted Manol-terminating sequences among O-glycans released from brain glycopeptides by reductive alkaline hydrolysis
22. Fluorescent neoglycolipids: Improved probes for oligosaccharide ligand discovery
23. Oligosaccharides that mediate mammalian cell-cell adhesion
24. Spectrum of sialylated and non-sialylated fuco-oligosaccharides bound by the endothelial-leukocyte adhesion molecule E-selectin. Dependence of the carbohydrate binding activity on E-selectin density
25. Multi-recognition capability of E-selectin in a dynamic flow system, as evidenced by differential effects of sialidases and anti-carbohydrate antibodies on selectin-mediated cell adhesion at low vs high wall shear stress: A preliminary note
26. Blood group-related oligosaccharides are ligands in cell-adhesion events
27. Glycolipid ligands for selectins support leukocyte tethering and rolling under physiologic flow conditions
28. a A superior oligosaccharide ligand for human E-selectin
29. Conformational studies on the selectin and natural killer cell receptor ligands sulfo- and sialyl-lacto-N-fucopentaoses (SuLNFPII and SLNFPII) using NMR spectroscopy and molecular dynamics simulations. Comparisons with the nonacidic parent molecule LNFPII
30. Structural requirements for the carbohydrate ligand of E-selectin
31. Expression of the α(1-3)fucosyltransferase Fuc-TVII in lymphoid aggregate high endothelial venules correlates with expression of L-selectin ligands
32. The alpha(1,3)fucosyltransferase Fuc-TVII controls leukocyte trafficking through an essential role in L-, E-, and P-selectin ligand biosynthesis
33. A single autosomal gene controlling the expression of the extended globoglycolipid carrying SSEA-1 determinant is responsible for the expression of two extended globogangliosides
34. L-Selectin and its biological ligands
35. a
36. The three members of the selectin receptor family recognize a common carbohydrate epitope, the sialyl Lewisx oligosaccharide
37. Enhanced interaction of L-selectin with the high enthelium venule ligand via selectively oxidized sialic acids
38. CD62/P-Selectin recognition of myeloid and tumor cell sulfatides
39. x oligosaccharides and the predominance of sulphate in this interaction demonstrated by binding studies with a series of lipid-linked oligosaccharides
40. Glycolipids are ligands for a lymphocyte homing receptor, L-selectin (LECAM-1), binding epitope in sulfated sugar chain
41. Higher-affinity oligosaccharide ligands for E-selectin
42. The HNK-I reactivity Sulfoglucuronyl Glycolipids are ligands for L-selectin and P-selectin but not E-selectin
43. Further studies of the binding specificity of the leukocyte adhesion molecule, L-selectin, towards sulfated oligosaccharides - Suggestion of a link between the selectin- and the integrin-mediated lymphocyte adhesion systems
44. x types: Relevance to anti-adhesion therapeutics
45. a
46. Structure of the O-glycans in GlyCAM-1, an endothelial-derived ligand for L-selectin
47. x ganglioside analogues for clarifying the real carbohydrate ligand structure of L-selectin
48. Studies on selectin blockers. 4. Structure-function relationships of sulfated sialyl Lewis X hexasaccharide ceramides toward E-P, P-, and L-selectin binding
49. x sequence 6-O-sulfated at N-acetylglucosamine rather than at galactose is the preferred ligand for L-selectin and de-N-acetylation of the sialic acid enhances the binding strength
50. Sulfated sialyl Lewis X, the putative L-selectin ligand, detected on endothelial cells of high endothelial venules by a distinct set of anti-sialyl Lewis X antibodies
51. Identification of a major carbohydrate capping group of the L-selectin ligand on high endothelial venules in human lymph nodes as 6-sulfo sialyl Lewis X
52. Reconstruction of functional L-selectin ligands on a cultured human endothelial cell line by cotransfection of α1→3 fucosyltransferase VII and newly cloned GlcNAcβ:6-sulfotransferase cDNA
53. Sulfotransferases of two specificities function in the reconstitution of high endothelial cell ligands for L-selectin
54. A novel, high endothelial venule-specific sulfotransferase expresses 6- sulfo sialyl Lewis(x), an L-selectin ligand displayed by CD34
55. Sulfation of a high endothelial venule-expressed ligand for L-selectin. Effects on tethering and rolling of lymphocytes
56. x analogues
57. x ganglioside: A superior ligand for human L-selectin
58. A novel ganglioside, de-N-acetyl-GM3 (II3NeuNH2LacCer), acting as a strong promoter for epidermal growth factor receptor kinase and as a stimulator for cell growth
59. Biosynthesis and turnover of O-acetyl and N-acetyl groups in the gangliosides of human melanoma cells
60. Expression of de-N-acetyl-gangliosides in human melanoma cells is induced by genistein or nocodazole
61. Regulation of selectin binding activity by cyclization of sialic acid moiety of carbohydrate ligands on human leukocytes
62. Sulfated disaccharide inhibitors of L-selectin: Deriving structural leads from a physiological selectin ligand
63. Endothelial heparan sulfate proteoglycans that bind to L-selectin have glucosamine residues with unsubstituted amino groups
64. Proteoglycans on endothelial cells present adhesion-inducing cytokines to leukocytes
65. Novel oligosaccharide ligands and ligand-processing pathways for the selectins
66. Biotinyl-L-3-(2-naphthyl)-alanine hydrazide derivatives of N-glycans: Versatile solid-phase probes for carbohydrate-recognition studies
67. Requirement of the core structure of a complex-type glycopeptide for the binding to immobilized lectins
68. Influence of oligosaccharide presentation on the interactions of carbohydrate sequence-specific antibodies and the selectins. Observations with biotinylated oligosaccharides
69. Differential recognition by conglutinin and mannan-binding protein of N-glycans presented on neoglycolipids and glycoproteins with special reference to complement glycoprotein C3 and ribonuclease B
70. Post-translational modifications of recombinant P-selectin glycoprotein ligand-I required for binding to P- and E-selectin
71. Synthetic studies on sialoglycoconjugates 22: Total synthesis of tumor-associated ganglioside, sialyl Lewis X