Flurbiprofen enantiomers inhibit inducible nitric oxide synthase expression in RAW 264.7 macrophages

Pharmaceutical Research

Volumn 18, Issue 2, 2001, Pages 151-156

  Hinz, B ^a   Brune, K ^a   Rau, T ^a   Pahl, A ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

2 arylpropionic acids; Cyclooxygenase 2; Flurbiprofen enantiomers; Inducible nitric oxide synthase; Stereoselectivity

Indexed keywords

ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 2; FLURBIPROFEN; NITRITE; PROSTAGLANDIN E2;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL CULTURE; CELL VIABILITY; DRUG EFFECT; DRUG MECHANISM; ENANTIOMER; ENZYME INHIBITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ASSAY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEREOCHEMISTRY;

ANIMALS; CELL LINE; CELL SURVIVAL; CYCLOOXYGENASE INHIBITORS; FLURBIPROFEN; GENE EXPRESSION; MACROPHAGES; MICE; MOLECULAR CONFORMATION; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II;

EID: 0034949092     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1011020132140     Document Type: Article

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