Abundant early expression of gpUL4 from a human cytomegalovirus mutant lacking a repressive upstream open reading frame

Journal of Virology

Volumn 75, Issue 15, 2001, Pages 7188-7192

  Alderete, J P ^a   Child, S J ^a   Geballe, A P ^a  

^a Fred Hutchinson Cancer Research Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN; GLYCOPROTEIN GP 38; UNCLASSIFIED DRUG;

ARTICLE; CELL CULTURE; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN CYTOMEGALOVIRUS; KINETICS; MUTATION; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; TRANSLATION INITIATION; VIRUS GENOME; VIRUS MUTANT; VIRUS REPLICATION;

CELL LINE; CYTOMEGALOVIRUS; GENE EXPRESSION REGULATION, VIRAL; HUMANS; MUTAGENESIS; OPEN READING FRAMES; RIBOSOMES; RNA, MESSENGER; RNA, VIRAL; VIRAL ENVELOPE PROTEINS;

EID: 0034947847     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.75.15.7188-7192.2001     Document Type: Article

References (20)

1. Translational effects of mutations and polymorphisms in a repressive upstream open reading frame of the human cytomegalovirus UL4 gene
2. Differentiation of human cytomegalovirus genotypes in immunocompromised patients on the basis of UL4 gene polymorphisms
3. Coding sequence-dependent ribosomal arrest at termination of translation
4. Inhibition of nascent-peptide release at translation termination
5. Mutational analysis of the translational signal in the human cytomegalovirus gpUL4 (gp48) transcript leader by retroviral infection
6. Ribosomal release without peptidyl tRNA hydrolysis at translation termination in a eukaryotic system
7. Translational inhibition by a human cytomegalovirus upstream open reading frame despite inefficient utilization of its AUG codon
8. Identification and expression of a human cytomegalovirus early glycoprotein
9. Translational inhibition mediated by a short upstream open reading frame in the human cytomegalovirus gpUL4 (gp48) transcript
10. Translational control by upstream open reading frames
11. Extension inhibition analysis of translation initiation complexes
12. Fast screening procedures for random transposon libraries of cloned herpesvirus genomes: Mutational analysis of human cytomegalovirus envelope glycoprotein genes
13. Defined large-scale alterations of the human cytomegalovirus genome constructed by cotransfection of overlapping cosmids
14. Cytomegaloviruses and their replication
15. Upstream open reading frames as regulators of mRNA translation
16. The products of human cytomegalovirus genes UL1-UL7, including gp48, are dispensable for growth in cell culture
17. Translational control of human cytomegalovirus gp48 expression
18. Site-specific stable insertion into the human cytomegalovirus genome of a foreign gene under control of the SV40 promoter
19. Ribosome stalling is responsible for arginine-specific translational attenuation in Neurospora crassa
20. Generation and effective enrichment of selectable human cytomegalovirus mutants using site-directed insertion of the neo gene