Ribosomal release without peptidyl tRNA hydrolysis at translation termination in a eukaryotic system

RNA

Volumn 4, Issue 2, 1998, Pages 181-188

  Cao, Jianhong ^a   Geballe, Adam P ^a,b  

^a Fred Hutchinson Cancer Research Center   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Cytomegalovirus; Toeprint; Translational control; UL4; Upstream open reading frame

Indexed keywords

MESSENGER RNA; TRANSFER RNA;

ARTICLE; CISTRON; CONTROLLED STUDY; EUKARYOTE; HUMAN CYTOMEGALOVIRUS; HYDROLYSIS; NONHUMAN; OPEN READING FRAME; PRIORITY JOURNAL; RIBOSOME; STOP CODON; TRANSLATION REGULATION;

EID: 0031940930     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. Anderson RP, Menninger JR. 1987. Tests of the ribosome editor hypothesis III. A mutant Escherichia coli with a defective ribosomes editor. Mol Gen Genet 209:313-318.
2. Bain JD, Switzer C, Chamberlain AR, Benner SA. 1992. Ribosome-mediated incorporation of a non-standard amino acid into a peptide through expansion of the genetic code. Nature 356:537-539.
3. Cabanas MJ, Vázquez D, Modolell J. 1978. Dual interference of hygromycin B with ribosomal translocation and with aminoacyl-tRNA recognition. Eur J Biochem 87:21-27.
4. Cao J, Geballe AP. 1995. Translational inhibition by a human cytomegalovirus upstream open reading frame despite inefficient utilization of its AUG codon. J Virol 69:1030-1036.
5. Cao J, Geballe AP. 1996a. Coding sequence-dependent ribosomal arrest at termination of translation. Mol Cell Biol 16:603-608.
6. Cao J, Geballe AP. 1996b. Inhibition of nascent-peptide release at translation termination. Mol Cell Biol 16:7109-7114.
7. Davies J, Grini L, Davis BD. 1965. Misreading of RNA codewords induced by aminoglycoside antibiotics. Mol Pharmacol 1:93-106.
8. Degnin CR, Schleiss MR, Cao J, Geballe AP. 1993. Translational inhibition mediated by a short upstream open reading frame in the human cytomegalovirus gpUL4 (gp48) transcript. J Virol 67:5514-5521.
9. Frolova L, Le Goff X, Rasmussen HH, Cheperegin S, Drugeon G, Kress M, Arman I, Haenni AL, Celis JE, Philippe M, Justesen J, Kisselev L. 1994. A highly conserved eukaryotic protein family possessing properties of polypeptide chain release factor. Nature (Lond) 372:701-703.
10. Geballe AP. 1996. Translational control mediated by upstream AUG codons. In: Hershey JWB, Mathews MB, Sonenberg N, eds. Translational control. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press, pp 173-197.
11. Gesteland RF, Atkins JF. 1996. Recoding: Dynamic reprogramming of translation. Annu Rev Biochem 65:741-768.
12. Grant CM, Hinnebusch AG. 1994. Effect of sequence context at stop codons on efficiency of reinitiation in GCN4 translational control. Mol Cell Biol 14:606-618.
13. Hartz D, McPheeters DS, Traut R, Gold L 1988. Extension inhibition analysis of translation initiation complexes. Methods Enzymol 164:419-425.
14. Hausner TP, Geigenmüller U, Nierhaus KH. 1988. The allosteric three-site model for the ribosomal elongation cycle. J Biol Chem 263:13103-13111.
15. Janosi L, Hara H, Zhang S, Kaji A. 1996a. Ribosome recycling by ribosome recycling factor (RRF) - An important but overlooked step of protein biosynthesis. Adv Biophys 32:121-201.
16. Janosi L. Ricker R, Kaji A. 1996b. Dual functions of ribosome recycling factor in protein biosynthesis: Disassembling the termination complex and preventing translational errors. Biochimie 78:959-969.
17. Kozak M. 1991. An analysis of vertebrate mRNA sequences: Intimations of translational control. J Cell Biol 115:887-903.
18. Lovett PS, Rogers EJ. 1996. Ribosome regulation by the nascent peptide. Microbiol Rev 60:366-385.
19. Macdonald JS, Goldberg IH. 1970. An effect of pactamycin on the initiation of protein synthesis in reticulocytes. Biochem Biophys Res Commun 47:1-8.
20. Menninger JR. 1976. Peptidyl transfer RNA dissociates during protein synthesis from ribosomes in Escherichia coli. J Biol Chem 251:3392-3398.
21. Menninger JR. 1979. Accumulation of peptidyl tRNA is lethal to Escherichia coli. J Bacteriol 137:694-696.
22. Moazed D, Noller HF. 1987. Interaction of antibiotics with functional sites in 16S ribosomal RNA. Nature (Lond) 327:389-394.
23. Nakamura Y, Ito K, Isaksson LA. 1996. Emerging understanding of translation termination. Cell 87:147-150.
24. Ouzounis C, Bork P, Casari G, Sander C. 1995. New protein functions in yeast chromosome VIII. Protein Sci 4:2424-2428.
25. Schleiss M, Degnin CR, Geballe AP. 1991. Translational inhibition mediated an upstream reading frame within the cytomegalovirus gp48 gene transcript leader. J Virol 65:6782-6789.
26. Tate WP, Brown CM. 1992. Translational termination: "Stop" for protein synthesis or "pause" for regulation of gene expression. Biochemistry 31:2443-2450.
27. Vázquez D, Zaera E, Humberto D, Jimenez A. 1982. Action of inhibitors of protein biosynthesis. In: Perez-Barcoff R, ed. Protein biosynthesis in eukaryotes. New York: Plenum, pp 311-337.
28. Wang Z, Sachs MS. 1997. Ribosome stalling is responsible for arginine-specific translational attenuation in Neurospora crassa. Mol Cell Biol. Forthcoming.
29. Zhouravleva G, Frolova L, Le Goff X, Le Guellec R, Inge-Vechtomov S, Kisselev L, Philippe M. 1995. Termination of translation in eukaryotes is governed by two interacting polypeptide chain release factors eRF1 and eRF3. EMBO J 14:4065-4072.