Coding sequence-dependent ribosomal arrest at termination of translation

Molecular and Cellular Biology

Volumn 16, Issue 2, 1996, Pages 603-608

  Cao, Jianhong ^b   Geballe, Adam P ^a  

^a Fred Hutchinson Cancer Research Center   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; VIRUS PROTEIN; VIRUS RNA;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GENETIC CODE; HUMAN CYTOMEGALOVIRUS; NONHUMAN; OPEN READING FRAME; PRIORITY JOURNAL; RABBIT; RETICULOCYTE LYSATE; RIBOSOME; TRANSLATION REGULATION;

ANIMALIA; EUKARYOTA; HUMAN HERPESVIRUS 5; ORYCTOLAGUS CUNICULUS;

EID: 0030067832     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.16.2.603     Document Type: Article

References (22)

1. Biegalke, B. J., and A. P. Geballe. 1990. Translational inhibition by cytomegalovirus transcript leaders Virology 177:657-667.
2. Cao, J., and A. P. Geballe. 1995 Translational inhibition by a human cytomegalovirus upstream open reading frame despite inefficient utilization of its AUG codon. J. Virol 69:1030-1036
3. Chang, C.-P., C. L. Malone, and M. F. Stinski. 1989. A human cytomegalovirus early gene has three inducible promoters that are regulated differentially at various times after infection. J. Virol. 63:281-290
4. Damiani, R. B., Jr., and S. R. Wessler. An upstream open reading frame represses expression of Lc, a member of the R/B family of maize transcriptional activators. Proc. Natl. Acad. Sci USA 90:8244-8248.
5. Degnin, C. R., M. R. Schleiss, J. Cao, and A. P. Geballe. 1993. Translational inhibition mediated by a short upstream open reading frame in the human cytomegalovirus gpUL4 (gp48) transcript. J. Virol 67:5514-5521.
6. Doohan, J. P., and C. E. Samuel. 1992. Biosynthesis of reovirus-specified polypeptides. ribosome pausing during the translation of reovirus S1 mRNA. Virology 186:409-425.
7. Geballe, A. P., and M. K. Gray. 1992. Variable inhibition of cell-free translation by HIV-1 leaders sequences Nucleic Acids Res. 20:4291-4297.
8. Geballe, A. P., and D. R. Morris. 1994 Initiation codons within 5′ leaders of mRNAs as regulators of translation. Trends Biochem Sci. 19:159-164
9. Grant, C. M., P. F. Miller, and A. G. Hinnebusch. 1994. Requirements for intercistronic distance and level of eukaryotic initiation factor 2 activity in reinitiation on GCN4 mRNA vary with the downstream cistron. Mol. Cell Biol. 14:2616-2628
10. Hartz, D., D. S. McPheeters, R. Traut, and L. Gold. 1988. Extension inhibition analysis of translation initiation complexes Methods Enzymol. 164: 419-425.
11. Hill, J. R., and D. R. Morris. 1993. Cell-specific translational regulation of S-adenosylmethionine decarboxylase mRNA: dependence on translation and coding capacity of the cis-acting upstream open reading frame. J. Biol Chem 268:726-731.
12. Kozak, M. 1987. Effects of intercistronic length on the efficiency of reinitiation by eukaryotic ribosomes. Mol. Cell Biol. 7:3438-3445
13. Kozak, M. 1989. The scanning model for translation: an update. J. Cell Biol 108:229-241.
14. Kozak, M. 1991 An analysis of vertebrate mRNA sequences: intimations of translational control. J. Cell Biol. 115:887-903.
15. Lodish, H. F., and M. Jacobsen. 1972. Regulation of hemoglobin synthesis Equal rates of translation and termination of α- and β-globin chains J Biol Chem. 247:3622-3629.
16. Lovett, P. S. 1990. Translational attenuation as the regulator of inducible cat genes. J. Bacteriol 172:1-6.
17. Meerovitch, K., and N. Sonenberg. 1993 Internal initiation of picornavirus RNA translation Semin Virol 4:217-227.
18. Palmiter, R. D. 1974. Magnesium precipitation of nbonucleoprotein com-plexes. Expedient techniques for the isolation of undergraded polysomes and messenger ribonucleic acid. Biochemistry 13:3606-3615.
19. 2 adrenergic receptor mRNA inhibits receptor synthesis J Biol. Chem. 269:4497-4505.
20. Schleiss, M., C. R. Degnin, and A. P. Geballe. 1991 Translational inhibition mediated an upstream reading frame within the cytomegalovirus gp48 gene transcript leader J. Virol 65:6782-6789.
21. Werner, M., A. Feller, F. Messenguy, and A. Pierard. 1987. The leader peptide of yeast gene cpal is essential for the translational repression of its expression. Cell 49:805-813.
22. Wolin, S. L., and P. Walter. 1988. Ribosome pausing and stacking during translation of a eukaryotic mRNA. EMBO J. 7:3559-3569.