The role of the endothelium for reperfusion injury

European Heart Journal, Supplement

Volumn 3, Issue C, 2001, Pages

  Pernow, John ^a   Gonon, A T ^a   Gourine, A ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Endothelin; Endothelium; Neutrophils; Nitric oxide; Reperfusion

Indexed keywords

ARGININE; CELL ADHESION MOLECULE; ENDOTHELIN; ENDOTHELIN RECEPTOR ANTAGONIST; NITRIC OXIDE; NITRIC OXIDE DONOR; SUPEROXIDE;

CELL ADHESION; CELL DEATH; HEART INFARCTION; HEART INFARCTION SIZE; HEART MUSCLE REPERFUSION; HEART PROTECTION; NEUTROPHIL CHEMOTAXIS; PRIORITY JOURNAL; REPERFUSION INJURY; REVIEW; VASCULAR ENDOTHELIUM; VASOCONSTRICTION; VASODILATATION;

EID: 0034947647     PISSN: 1520765X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1520-765X(01)90026-4     Document Type: Review

References (40)

1. Myocardial reperfusion: A double edged sword
2. Myocardial infarct extension during reperfusion after coronary artery occlusion: Pathological evidence
3. Reperfusion induced injury: Manifestations, mechanisms, and clinical relevance
4. The role of neutrophils in myocardial ischemia-reperfusion injury
5. The pathogenesis of cardiovascular disease: Role of the endothelium as a target and mediator
6. Reperfusion after coronary occlusion in dogs impairs endothelium-dependent relaxation to acetylcholine and augments contractile reactivity in vitro
7. Time course of endothelial dysfunction and myocardial injury during myocardial ischemia and reperfusion in the cat
8. Reduction of the extent of ischemic myocardial injury by neutrophil depletion in the dog
9. Neutrophil depletion limited to reperfusion reduces myocardial infarct size after 90 minutes of ischemia. Evidence for neutrophil-mediated reperfusion injury
10. Role of the beta2-integrins and immunoglobulin superfamily members in myocardial ischemia-reperfusion
11. Reduction of experimental canine myocardial reperfusion injury by a monoclonal antibody (anti-Mol, anti-CD11b) that inhibits leukocyte adhesion
12. Sustained limitation of myocardial reperfusion injury by a monoclonal antibody that alters leukocyte function
13. Coronary endothelial and cardiac protective effects of a monoclonal antibody to intercellular adhesion molecule-1 in myocardial ischemia and reperfusion
14. In vivo neutralization of P-selectin protects feline heart and endothelium in myocardial ischemia and reperfusion injury
15. Monoclonal antibody to L-selectin attenuates neutrophil accumulation and protects ischemic reperfused cat myocardium
16. Blockade of platelet endothelial cell adhesion molecule-1 protects against myocardial ischemia and reperfusion injury in cats
17. Nitric oxide: Physiology, pathophysiology and pharmacology
18. L-arginine enhances functional recovery and Ca(2+)-dependent nitric oxide synthase activity after ischemia and reperfusion in the rat heart
19. The role of nitric oxide and cell adhesion molecules on the microcirculation in ischaemia-reperfusion
20. Nitric oxide signaling in ischemic heart
21. The role of L-arginine in ameliorating reperfusion injury after myocardial ischemia in the cat
22. The protective effect of L-arginine on myocardial injury and endothelial function following ischaemia and reperfusion in the pig
23. Role of L-arginine in preventing myocardial and endothelial injury following ischaemia/reperfusion in the rat isolated heart
24. Intracoronary L-arginine during reperfusion improves endothelial function and reduces infarct size
25. The role of the L-arginine/nitric oxide pathway in myocardial ischaemic and reperfusion injury
26. The cardiovascular effects and implications of peroxynitrite
27. Intracoronary nitric oxide improves post-ischemic coronary blood flow and myocardial contractile function
28. Simvastatin preserves the ischemic-reperfused myocardium in normocholesterolemic rat hearts
29. Endothelin: A novel potent vasoconstrictor peptide produced by vascular endothelial cells
30. Endothelins: Molecular biology, biochemistry, pharmacology, physiology, and pathophysiology
31. Endothelin in myocardial ischaemia and reperfusion
32. Contribution of endogenous endothelin to the extension of myocardial infarct size in rats
33. The endothelin-1 receptor antagonist BQ-123 reduces infarct size in a canine model of coronary occlusion and reperfusion
34. Protective effects of non-peptide endothelin receptor antagonist bosentan on myocardial ischaemic and reperfusion injury in the pig
35. The novel non-peptide selective endothelin A receptor antagonist LU 135 252 protects against myocardial ischaemic and reperfusion injury in the pig
36. Cardioprotection from ischemia and reperfusion injury by an endothelin A-receptor antagonist in relation to nitric oxide production
37. Ischemia-reperfusion injury at the microvascular level: Treatment by endothelin A-selective antagonist and evaluation by myocardial contrast echocardiography
38. The endothelin A receptor antagonist LU 135 252 protects the myocardium from neutrophil injury during ischaemia/reperfusion
39. The role of endothelin, protein kinase C and free radicals in the mechanism of the post-ischemic endothelial dysfunction in guinea-pig hearts
40. Involvement of nitric oxide in cardioprotective effect of endothelin receptor antagonist during ischemia-reperfusion