Induction by bombesin of peritoneal metastasis of gastric cancers induced by N-methyl-N′-nitro-N-nitrosoguanidine in Wistar rats

Gastric Cancer

Volumn 4, Issue 1, 2001, Pages 14-19

  Tatsuta, Masaharu ^a   Iishi, Hiroyasu ^a   Baba, Miyako ^a   Narahara, Hiroyuki ^a   Uedo, Noriya ^a   Yano, Hiroyuki ^a   Yamamoto, Reiko ^a   Mukai, Mutsuko ^a   Akedo, Hitoshi ^a  

^a OSAKA MEDICAL CENTER FOR CANCER AND CARDIOVASCULAR DISEASES   (Japan)

Author keywords

Animal model; Bombesin; Gastric cancer; N Methyl N nitro N nitrosoguanidine; Peritoneal metastasis

Indexed keywords

BOMBESIN; METHYLNITRONITROSOGUANIDINE; OLIVE OIL; RHO FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INVASION; CONTROLLED STUDY; DRUG INDUCED DISEASE; HISTOLOGY; IMMUNOBLOTTING; INCIDENCE; MALE; NONHUMAN; PERITONEUM METASTASIS; PRIORITY JOURNAL; RAT; RAT STRAIN; STOMACH CANCER;

ANIMALS; BOMBESIN; CARCINOGENS; MALE; METHYLNITRONITROSOGUANIDINE; PERITONEAL NEOPLASMS; RATS; RATS, WISTAR; RHO GTP-BINDING PROTEINS; STOMACH NEOPLASMS;

EID: 0034946446     PISSN: 14363291     EISSN: None     Source Type: Journal    
DOI: 10.1007/s101200100011     Document Type: Article

References (31)

1. Enhancement by bombesin of colon carcinogenesis and metastasis induced by azoxymethane in Wistar rats
2. Isolation and structure of bombesin and alytensin, two analogous active peptides from the skin of the European amphibians "Bombina" and "Alytes"
3. Bombesin-like immunoreactivity in human gastrointestinal tract
4. Localization of specific binding sites for bombesin in the canine gastrointestinal tract
5. Mammalian bombesin-like peptides; neuromodulators of gastric function and autocrine regulators of lung cancer growth
6. Peptidergic regulations of cell proliferation through multiple signaling pathways
7. Peptone stimulates gastrin secretion from the stomach by activating bombesin/GRP and cholinergic neurons
8. Promotion by bombesin of gastric carcinogenesis induced by N-methyl-N′-nitro-N-nitrosoguanidine in Wistar rats
9. Effect of cimetidine on inhibition by tetragastrin of carcinogenesis in Wistar rat
10. Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton
11. Bombesin, calcium homeostasis and tumor growth
12. 2+ signaling and insulin secretion in β-cells
13. Bombesin stimulates adhesion, spreading, lamellipodia formation, and proliferation in the human colon carcinoma Isreco 1 cell line
14. Bombesin stimulates in vitro growth of human breast cancer independent of estrogen receptors status
15. Bombesin-evoked gastrin release and calcium signaling in human antral G cells in culture
16. 2+ wave propagation in mouse pancreatic acinar cells
17. A human gastric cancer cell line possesses a functional receptor for gastrin-releasing peptide
18. Serum requirement for in vitro invasion by tumor cells
19. Inhibition of in vitro tumor cell invasion by ginsenoside Rg3
20. Multiple protein kinase pathways are involved in gastrin-releasing peptide receptor-regulated secretion
21. Mitogen-activated protein kinase (MAPK) regulates the expression of progelatinase B (MMP-9) in breast epithelial cells
22. Lysophosphatidic acid induces threonine phosphorylation of Tiam1 in Swiss 3T3 fibroblasts via activation of protein kinase C
23. Signal transduction pathways regulating Rho-mediated stress fiber formation: Requirement for a tyrosine kinase
24. Activation of the small GTP-binding protein rho and rac by growth factor receptors
25. 3 exoenzyme blocks the tyrosine phosphorylation of p125 FAK and paxillin induced by bombesin and endothelin
26. Tyrosine phosphorylation of paxillin and focal adhesin kinase by activation of muscarinic m3 receptor is dependent on integrin engagement by the extracellular matrix
27. Rho stimulates tyrosine phosphorylation of focal adhesion kinase, p130 and paxillin
28. Y-27632, an inhibitor of Rho-associated protein kinases, suppresses tumor cell invasion via regulation of focal adhesion kinase