Tolbutamide and diazoxide modulate phospholipase C-linked Ca2+ signaling and insulin secretion from β-cells

American Journal of Physiology - Endocrinology and Metabolism

Volumn 278, Issue 4 41-4, 2000, Pages

  Schöfl, Christof ^a   Börger, Julia ^a   Mader, Thilo ^a   Waring, Mark ^a   Von Zur Mühlen, Alexander ^a   Brabant, Georg ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Adenosine 5' triphosphate sensitive potassium channels; Insulin secretion; Intracellular calcium; Phospholipase C

Indexed keywords

1,4 DIHYDRO 2,6 DIMETHYL 5 NITRO 4 [2 (TRIFLUOROMETHYL)PHENYL] 3 PYRIDINECARBOXYLIC ACID METHYL ESTER; ADENOSINE TRIPHOSPHATE; ARGIPRESSIN; BOMBESIN; CALCIUM; DIAZOXIDE; GLUCOSE; INSULIN; NIFEDIPINE; PHOSPHOLIPASE C; POTASSIUM CHANNEL; TOLBUTAMIDE;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; INSULIN RELEASE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0034002040     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.2000.278.4.e639     Document Type: Article

References (40)

1. Balla T, Nakanishi S, and Catt KJ. Cation sensitivity of inositol 1,4,5-trisphosphate production and metabolism in agonist-stimulated adrenal glomerulosa cells. J Biol Chem 269: 16101-16107, 1994.
2. 3- and calcium gated channels from endoplasmic reticulum of cerebellum. Nature (Lond.) 351: 751-754, 1991.
3. + channels: generating excitement in pancreatic β-cells. Diabetes 45: 845-853, 1996.
4. Eliasson L, Renström E, Ämmälä C, Berggren PO, Bertorello AM, Bokvist K, Chibalin A, Deeny JT, Flatt PR, Gäbel J, Gromada J, Larsson O, Lindström P, Rhodes CJ, and Rorsman P. PKC-dependent stimulation of exocytosis by sulfonylureas in pancreatic β-cells. Science 271: 813-815, 1996.
5. Flatt PR, Shibier O, Szecowka J, and Berggren PO. New perspectives on the actions of sulfonylureas and hyperglycaemic sulphonamides on the pancreatic β-cell. Diabetes Metab 20: 157-162, 1994.
6. Gao ZY, Drews G, Nenquin M, Plant TD, and Henquin JC. Mechanisms of the stimulation of insulin release by arginine-vasopressin in normal mouse islets. J Biol Chem 265: 15724-15730, 1990.
7. + channels in mouse β-cells. J Clin Invest 89: 1288-1295, 1992.
8. Girard S and Clapham D. Acceleration of intracellular calcium waves in Xenopus oocytes by calcium influx. Science 260: 229-222, 1993.
9. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260: 3440-3450, 1985.
10. 2+ in hyperpolarized pancreatic β-cells. Pflügers Arch 419: 639-643, 1991.
11. 2+ release at the endoplasmic reticulum in rat pancreatic β-cells. Cell Calcium 17:21-31, 1995.
12. Hill RS and Boyd III AE. Perifusion of a clonal cell line of simian virus 40-transformed beta cells. Insulin secretory dynamics in response to glucose, 3-isobutyl methyxanthine and potassium. Diabetes 34:115-120, 1985.
13. Hughes SJ, Carpinelli A, Niki I, Nicks JL, and Ashcroft SJH. Stimulation of insulin release by vasopressin in the clonal β-cell line, HIT-T15: the role of protein kinase C. J Mol Endocrinol 8: 145-153, 1992.
14. Ipp E and Unger RH. Bombesin stimulates the release of insulin and glucagon, but not pancreatic somatostatin, from the isolated perfused dog pancreas. Endocr Res Commun 6: 37-42, 1979.
15. 0 or by the expression of their active Gα subunits. EMBO J 14: 3635-3644, 1995.
16. Li G, Wollheim CB, and Pralong WF. Oscillations of cytosolic free calcium in bombesin-stimulated HIT-T15 cells. Cell Calcium 19: 535-546, 1996.
17. 2+ entry in insulin-releasing pancreatic beta-cells. Cell Calcium 22: 277-286, 1997.
18. Lu M, Soltoff SP, Yaney GC, and Boyd III AE. The mechanisms underlying the glucose dependence of arginine vasopressin-induced insulin secretion in β-cells. Endocrinology 132: 2141-2148, 1993.
19. Malaisse WJ. Metabolic signaling of insulin secretion. Diabetes Rev 4: 145-159, 1996.
20. 2+ in β-cells. Diabetes 47: 365-373, 1998.
21. 2+ concentration in insulin-secreting cells. EMBO J 8: 3595-3599, 1989.
22. Newgard CB and McGarry JD. Metabolic coupling factors in pancreatic β-cell signal transduction. Annu Rev Biochem 64: 689-719, 1995.
23. Panten U, Schwanstecher M, and Schwanstecher C. Sulfonylurea receptors and mechanism of sulfonylurea action. Exp Clin Endocrinol Diabetes 104: 1-9, 1996.
24. 2+ in carbamylcholine-stimulated insulinoma cells. J Biol Chem 263: 11044-11047, 1988.
25. Regazzi R, Li G, Deshusses J, and Wollheim CB. Stimulus-response coupling in insulin-secreting HIT cells. J Biol Chem 265: 15003-15009, 1990.
26. Renström E and Rorsman P. Intracellular tolbutamide stimulates calcium-dependent exocytosis in pancreatic B-cells (Abstract). Diabetologia 39, Suppl 1: A229, 1996.
27. Samols E and Stagner JI. Intra-islet cell-cell interactions and insulin secretion. Diabetes Rev 4: 207-223, 1996.
28. Santerre RF, Cook RA, Crisel RMD, Sharp JD, Schmidt RJ, Williams DC, and Wilson CP. Insulin synthesis in a clonal cell line of simian virus 40-transformed hamster pancreatic beta cells. Proc Natl Acad Sci USA 78: 4339-4343, 1981.
29. +-ATP channel-independent pathway of regulation of insulin secretion by glucose. Diabetes 47: 1713-1721, 1998.
30. 2+ through voltage-dependent and voltage independent channels in single HIT cells. Cell Calcium 19: 485-493, 1996.
31. 2+ signaling and insulin secretion by phospholipase C-linked hormones in HIT cells. Endocrinology 137: 3026-3032, 1996.
32. Schöfl C, Schulte P, Rössig L, von zur Mühlen A, and Brabant G. Vasopressin induces frequency-modulated repetitive calcium transients in single insulin-secreting HIT cells. Mol Cell Endocrinol 108: 185-192, 1995.
33. + channel. Diabetes Rev 4: 177-190, 1996.
34. Swope SL and Schonbrunn A. Bombesin stimulates insulin secretion by a pancreatic islet cell line. Proc Natl Acad Sci USA 81: 1822-1826, 1984.
35. Takemura H, Hughes AR, Thastrup O, and Putney, Jr JW. Activation of calcium entry by the tumor promoter thapsigargin in parotid acinar cells. J Biol Chem 264: 12266-12271, 1989.
36. 2+ uptake, electrical activity, and insulin secretion of mouse pancreatic islets. Endocrinology 128: 3247-3252, 1991.
37. + channels. EMBO J 7: 2443-2449, 1988.
38. 2+ and G-proteins. Diabetes Rev 4: 276-297, 1996.
39. 2+ stores activates a maitotoxin-sensitive nonselective cationic current in β-cells. J Biol Chem 269: 32055-32058, 1994.
40. Zawalich WS. Regulation of insulin secretion by phosphoinositide-specific phospholipase C and protein kinase C activation. Diabetes Rev 4: 160-176, 1996.