Dietary probiotic supplementation enhances natural killer cell activity in the elderly: An investigation of age-related immunological changes

Journal of Clinical Immunology

Volumn 21, Issue 4, 2001, Pages 264-271

  Gill, H S ^a   Rutherfurd, K J ^a   Cross, M L ^a  

^a MASSEY UNIVERSITY   (New Zealand)

Author keywords

Immunosenescence; Natural killer cells; Probiotics; Tumoricidal activity

Indexed keywords

PROBIOTIC AGENT;

ADULT; AGED; AGING; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL ACTIVITY; CELLULAR IMMUNITY; CONTROLLED STUDY; DIET SUPPLEMENTATION; FEMALE; HUMAN; HUMAN EXPERIMENT; IMMUNOREACTIVITY; IMMUNOSTIMULATION; INFECTION RISK; LACTIC ACID BACTERIUM; LACTOBACILLUS RHAMNOSUS; LYMPHOID CELL; MALE; NATURAL KILLER CELL; NORMAL HUMAN; PRIORITY JOURNAL;

AGED; AGED, 80 AND OVER; AGING; BIFIDOBACTERIUM; CYTOTOXICITY, IMMUNOLOGIC; FEMALE; HUMANS; IMMUNITY, CELLULAR; K562 CELLS; KILLER CELLS, NATURAL; LACTOBACILLUS; MALE; MIDDLE AGED; PROBIOTICS;

EID: 0034946215     PISSN: 02719142     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1010979225018     Document Type: Article

References (37)

1. Active ageing makes the difference
2. Decreased immunity and increased morbidity in the elderly
3. The role of nutrition in immunity in the aged
4. Cell mediated immunity changes in ageing. Relative importance of cell subpopulation switches and of nutritional factors
5. Protein undernutrition as the major cause of decreased immune function in the elderly: Clinical and functional implications
6. Graying of the immune system: Can nutrient supplements improve immunity in the elderly?
7. Monocytes are responsible for depressed natural killer (NK) activity in both young and elderly low NK responders
8. Nutrition and immunity in the elderly: Clinical significance
9. Natural killer cell function is not diminished in the healthy aged and is proportional to the number of NK cells in the peripheral blood
10. Effects of one year of supplementation with zinc and other micronutrients on cellular immunity in the elderly
11. Effect of vitamin and trace-element supplementation on immune responses and infection in elderly subjects
12. Natural killer ceil activity in elderly men is enhanced by beta-carotene supplementation
13. Optimizing immunity and gut function in the elderly
14. Augmentation of mouse natural killer cell activity by Lactobacillus casei and its surface antigens
15. Modulating immune responses with probiotic bacteria
16. Anti-tumor activity of Lactobacillus casei on Lewis lung carcinoma and line-10 hepatoma in syngeneic mice and guinea pigs
17. Host-mediated antiviral activity of Lactobacillus casei against cytomegalovirus infection in mice
18. Enhancement of immuno-activities by oral administration of Lactobacillus casei in colorectal cancer patients
19. Preventive effect of a Lactobacillus casei preparation on the recurrence of superficial bladder cancer in a double-blind trial
20. Biotherapeutic agents: A neglected modality for the prevention and treatment of selected intestinal and vaginal infections
21. Probiotics and prebiotics: Can regulating the activities of intestinal bacteria benefit health?
22. Stimulation of the immune system by lactic cultures
23. Enhancement of natural and acquired immunity by Lactobacillus rhamnosus (HN001), Lactobacillus acidophilus (HN017) and Bifidobacterium lactis (HN019)
24. Enhancement of natural immune function by dietary consumption of Bifidobacterium lactis (HN019)
25. Selection and characterisation of Lactobacillus and Bifidobacterium strains for use as probiotics
26. Clinical applications of probiotic bacteria
27. Effect of vitamin and trace element supplementation on immune indices in healthy elderly
28. Beta-carotene-induced enhancement of natural killer cell activity in elderly men: An investigation of the role of cytokines
29. Role of food in the stimulation of cytokine production
30. Effect of the oral administration of Lactobacillus brevis subsp. coagulans on interferon-α producing capacity in humans
31. Lactobacilli from human gastrointestinal mucosa are strong stimulators of IL-12 production
32. Lactobacilli and streptococci induce interleukin-12 (IL-12), IL-18 and gamma-interferon production in human peripheral blood mononuclear cells
33. Activation of human peripheral blood mononuclear cells by nonpathogenic bacteria in vitro: Evidence of NK cells as primary targets
34. Lactic acid bacterium potently induces the production of interleukin-12 and interferon-γ by mouse splenocytes
35. Antitumor effect of heat-killed Lactobacillus ptantarum L-137 through restoration of impaired interleukin-12 production in tumor-bearing mice
36. Natural killing and antibody-dependent cytotoxicity by lymphocyte subpopulations in young and aging humans
37. Immunostimulatory action of a complete oral supplement on elderly subjects with denutrition