Molecular dynamics simulation of the antimicrobial salivary peptide histatin-5 in water and in trifluoroethanol: A microscopic description of the water destructuring effect

Journal of Peptide Research

Volumn 58, Issue 1, 2001, Pages 45-55

  Iovino, M ^a   Falconi, M ^a   Marcellini, A ^a   Desideri, Alessandro ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

helix destabilization; 2,2,2 trifluoroethanol; Histatin 5; Molecular dynamics simulation; Solvent residence time

Indexed keywords

HISTATIN; TRIFLUOROETHANOL;

ALPHA HELIX; ANTIMICROBIAL ACTIVITY; ARTICLE; CIRCULAR DICHROISM; HYDROGEN BOND; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; PROTEIN STRUCTURE;

AMINO ACID SEQUENCE; ANTIFUNGAL AGENTS; CIRCULAR DICHROISM; COMPUTER SIMULATION; HYDROGEN BONDING; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; SALIVARY PROTEINS; SOLVENTS; TRIFLUOROETHANOL; WATER;

EID: 0034945756     PISSN: 1397002X     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-3011.2001.00885.x     Document Type: Article

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