An ion exchange liquid chromatography/mass spectrometry method for the determination of reduced and oxidized glutathione and glutathione conjugates in hepatocytes

Journal of Pharmaceutical and Biomedical Analysis

Volumn 26, Issue 1, 2001, Pages 131-142

  Loughlin, Amy F ^a   Skiles, Gary L ^a   Alberts, David W ^a   Schaefer, William H ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

GSH menadione conjugate; Quinone moiety; Selected ion monitoring (SIM)

Indexed keywords

1,4 BENZOQUINONE; ACETONITRILE; GLUTATHIONE; GLUTATHIONE DISULFIDE; GLUTATHIONE MENADIONE CONJUGATE; GLUTATHIONE PRECOCENE CONJUGATE; IODOACETIC ACID; MENADIONE; PRECOCENE I; UNCLASSIFIED DRUG;

ACCURACY; ANALYTIC METHOD; ANIMAL CELL; ARTICLE; CELL LEVEL; CONJUGATE; CONTROLLED STUDY; DEVICE; DOSE TIME EFFECT RELATION; DRUG DETERMINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTERMETHOD COMPARISON; ION EXCHANGE CHROMATOGRAPHY; ION MONITORING; LIVER CELL; MASS SPECTROMETER; MASS SPECTROMETRY; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; QUANTITATIVE ASSAY; RAT;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, ION EXCHANGE; GLUTATHIONE; GLUTATHIONE DISULFIDE; LIVER; MASS SPECTROMETRY; RATS; VITAMIN K;

EID: 0034933062     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0731-7085(01)00402-2     Document Type: Article

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