The relative importance of oxidative stress versus arylation in the mechanism of quinone-induced cytotoxicity to platelets

Chemico-Biological Interactions

Volumn 113, Issue 2, 1998, Pages

  Seung, Sang Ae ^a   Lee, Joo Young ^a   Lee, Moo Yeol ^b   Park, Jong Sei ^b   Chung, Jin Ho ^a  

^a Seoul National University   (South Korea)

^b Korea Food and Drug Administration   (South Korea)

Author keywords

2,3 Dimethoxy 1,4 naphthoquinone; Arylation; Benzoquinone; Cytotoxicity; Menadione; Oxidative stress; Platelets; Redox cycling

Indexed keywords

2,3 DIMETHOXY 1,4 NAPHTHOQUINONE; BENZOQUINONE; MENADIONE; QUINONE DERIVATIVE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; FEMALE; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; RAT; THROMBOCYTE; XENOBIOTIC METABOLISM;

ALKYLATION; ANIMALS; BENZOQUINONES; BLOOD PLATELETS; CELL SURVIVAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEMALE; GLUTATHIONE; HOMEOSTASIS; L-LACTATE DEHYDROGENASE; NAPHTHOQUINONES; OXIDATIVE STRESS; OXYGEN CONSUMPTION; QUINONES; RATS; RATS, SPRAGUE-DAWLEY; VITAMIN K;

EID: 0032524063     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-2797(98)00024-6     Document Type: Article

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