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Volumn 9, Issue 6, 2001, Pages 1639-1647

Synthesis and study of a cyclic angiotensin II antagonist analogue reveals the role of π*-π* interactions in the C-terminal aromatic residue for agonist activity and its structure resemblance with AT1 non-peptide antagonists

(12) Polevaya, Ludmila a Mavromoustakos, Thomas b Zoumboulakis, Panagiotis b Grdadolnik, Simona Golic c Roumelioti, Panagiota d Giatas, Nektarios d Mutule, Ilze a Keivish, Tatjana a Vlahakos, Demetrios V e Iliodromitis, Efstathios K e Kremastinos, Dimitrios Th e Matsoukas, John d

a LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (Latvia)

b Institute of Organic and Pharmaceutical Chemistry (Greece)

c NATIONAL INSTITUTE OF CHEMISTRY (Slovenia)

d UNIVERSITY OF PATRAS (Greece)

e ONASSIS CARDIAC SURGERY CENTER (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN; ANGIOTENSIN 2 RECEPTOR ANTAGONIST; ANGIOTENSIN II DERIVATIVE; EPROSARTAN; IRBESARTAN; LOSARTAN;

AGONIST; ANIMAL EXPERIMENT; ARTICLE; CARDIOVASCULAR RESPONSE; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; MALE; MOLECULAR DYNAMICS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RABBIT;

ACRYLATES; ANGIOTENSIN II; ANIMALS; ANTIHYPERTENSIVE AGENTS; BIOCHEMISTRY; BIPHENYL COMPOUNDS; DRUG DESIGN; IMIDAZOLES; LOSARTAN; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MODELS, MOLECULAR; PEPTIDES, CYCLIC; RABBITS; STRUCTURE-ACTIVITY RELATIONSHIP; TETRAZOLES; THIOPHENES;

EID: 0034930426 PISSN: 09680896 EISSN: None Source Type: Journal
DOI: 10.1016/S0968-0896(01)00059-1 Document Type: Article

Times cited : (35)

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