The astrocyte/meningeal cell interface - A barrier to successful nerve regeneration?

Cell and Tissue Research

Volumn 305, Issue 2, 2001, Pages 267-273

  Shearer, Morven C ^a   Fawcett, James W ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Fibrotic scar; Glia limitans; Glial scar; Meningeal; Regeneration

Indexed keywords

CELL SURFACE MARKER; MATRIX PROTEIN;

ASTROCYTE; CELL INTERACTION; CELL TYPE; COCULTURE; HUMAN; MENINX; NERVE FIBER GROWTH; NERVE REGENERATION; NONHUMAN; PRIORITY JOURNAL; REVIEW;

ANIMALS; ASTROCYTES; CENTRAL NERVOUS SYSTEM; GROWTH CONES; MENINGES; NERVE REGENERATION; NEURITES; SIGNAL TRANSDUCTION;

MAMMALIA;

EID: 0034926852     PISSN: 0302766X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004410100384     Document Type: Review

References (44)

1. Interactions between meningeal cells and astrocytes in vivo and in vitro
2. Neurocan is upregulated in injured brain and in cytokine-treated astrocytes
3. Chondroitinase ABC delivered to the site of a spinal cord injury upregulates GAP-43 expression in dorsal root ganglion neurons
4. Recovery from spinal cord injury mediated by antibodies to neurite growth inhibitors
5. Chondroitin sulfate as a regulator of neuronal patterning in the retina
6. Prior exposure to neurotrophins blocks inhibition of axonal regeneration by MAG and myelin via a cAMP-dependent mechanism
7. Ultrastructure study on meningeal regeneration and meningoglial relationships after cerebral stab wound in the adult rat
8. Driving the growth cone
9. Two membrane fractions from rat central myelin with inhibitory properties for neurite outgrowth and fibroblast spreading
10. Antibody against myelin-associated inhibitor of neurite growth neutralizes nonpermissive substrate properties of CNS white matter
11. Regeneration of adult axons in white matter tracts of the central nervous system
12. Robust regeneration of adult sensory axons in degenerating white matter of the adult rat spinal cord
13. Comparing astrocytic cell lines that are inhibitory or permissive for axon growth: The major axon-inhibitory proteoglycan is NG2
14. Entorhinal cortex lesion in adult rats induces the expression of the neuronal chondroitin sulfate proteoglycan neurocan in reactive astrocytes
15. Immunocytochemical characterization of reactive optic nerve astrocytes and meningeal cells
16. Developmental expression pattern and functional analysis of NOGO (formerly NI-35/250), a major inhibitor of CNS regeneration
17. Three morphologically distinct types of interface develop between adult host and fetal brain transplants: Implications for scar formation in the adult central nervous system
18. Inactivation of Rho signaling pathway promotes CNS axon regeneration
19. Development and differentiation of glial precursor cells in the rat cerebellum
20. Topical glucocorticoids modulate the lesion interface after cerebral cortical stab wounds in adult rats
21. A time course for the focal elevation of synthesis of basic fibroblast growth factor and one of its high-affinity receptors (flg) following a localized cortical brain injury
22. Effects of transforming growth factor b1 on scar production in the injured central nervous system of the rat
23. Inhibition of glial scarring in the injured rat brain by a recombinant human monoclonal antibody to transforming growth factor-β2
24. Decorin attenuates gliotic scar formation in the rat cerebral hemisphere
25. Nervous tissue proteoglycans
26. Observations on the astrocyte response to a cerebral stab wound in adult rats
27. Injury-induced proteoglycans inhibit the potential for laminin-mediated axon growth on astrocytic scars
28. The chondroitin sulfate proteoglycans neurocan and phosphacan are expressed by reactive astrocytes in the chronic CNS glial scar
29. Identification of myelin-associated glycoprotein as a major myelin-derived inhibitor of neurite growth
30. Extensive axon regeneration following in vivo treatment of rat brain with chondroitinase ABC
31. A novel role for myelin associated glycoprotein as an inhibitor of axonal regeneration
32. Expression of the gene encoding the chemorepellent semaphorin III is induced in the fibroblast component of neural scar tissue formed following injuries of adult but not neonatal CNS
33. Glial inhibition of nerve regeneration in the mature mammalian CNS
34. Inhibition of neurite outgrowth on astroglial scars in vitro
35. Axonal regeneration in the rat spinal cord produced by an antibody against myelin-associated neurite growth inhibitors
36. Cicatrix formation in rat cerebral cortex as revealed by electron microscopy
37. Increased axon regeneration in astrocytes grown in the presence of proteoglycan synthesis inhibitors
38. Sulfated proteoglycans in astroglial barriers inhibit neurite outgrowth in vitro
39. Inhibition of collagen IV deposition promotes regeneration of injured CNS axons
40. Cocultures of meningeal and astrocytic cells - A model for the formation of the glial-limiting membrane
41. Soluble myelin-associated glycoprotein (MAG) found in vivo inhibits axonal regeneration