Suppression of tumor growth and metastasis by dietary fish oil combined with vitamins E and C and cisplatin

Cancer Chemotherapy and Pharmacology

Volumn 47, Issue 1, 2001, Pages 34-40

  Yam, D ^a   Peled, A ^a   Shinitzky, M ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

3 PUFA; Chemotherapy; Lipid peroxidation; Tumor suppression; Vitamins E + C

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; CISPLATIN; CORN OIL; FERROUS ION; FISH OIL; IRON SALT; OMEGA 3 FATTY ACID; SOYBEAN OIL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CHEMOTHERAPY; CANCER INHIBITION; CONTROLLED STUDY; DIET SUPPLEMENTATION; DIETARY INTAKE; DRUG EFFECT; FEMALE; HISTOPATHOLOGY; LEWIS CARCINOMA; METASTASIS; METASTASIS INHIBITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; TUMOR GROWTH;

ANALYSIS OF VARIANCE; ANIMALS; ANTINEOPLASTIC AGENTS; ASCORBIC ACID; CARCINOMA, LEWIS LUNG; CISPLATIN; COMBINED MODALITY THERAPY; DRUG SCREENING ASSAYS, ANTITUMOR; FATTY ACIDS, OMEGA-3; FEMALE; MICE; MICE, INBRED C57BL; SOYBEAN OIL; VITAMIN E;

EID: 0034924035     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002800000205     Document Type: Article

References (55)

1. Effect of dietary fat on tumorigenesis in the mouse mammary gland
2. Effect of omega-3 fatty acids on rectal mucosa cell proliferation in subjects at risk for colon cancer
3. Selective killing of human cancer cells by polyunsaturated fatty acids
4. Differential killing of human carcinoma cells supplemented with n-3 and n-6 polyunsaturated fatty acids
5. The effect of year of birth on the breast cancer age-incidence curve in Iceland
6. Cancer mortality among Alaskan natives 1960-69
7. Epidemiologic evidence for vitamin C and E in cancer prevention
8. Low dose eicosapentaenoic or docosahexaenoic acid administration modifies fatty acid composition and does no affect susceptibility to oxidative stress in rat erythrocytes and tissues
9. Fat, fish, fish oil and cancer
10. Influence of n-3 fatty acids on the growth of human breast cancer cells in vitro: Relationship to peroxides and vitamin E
11. Antioxidants enhance the cytotoxicity of chemotherapeutic agents in colorectal cancer: A p 53-independent induction of 21 WAF1/CIPI via C/EPB beta
12. Supplementation with antioxidants prior to bone marrow transplantation
13. Effect of an alphalinolenic acid-rich diet on rat mammary tumor growth depends on the dietary oxidative status
14. Platinum (II) complexes containing iminoethers: A trans platinum antitumor agent
15. Uptake and distribution of cis unsaturated fatty acids and their effects on free radical generation in normal and tumor cells in vitro
16. Antioxidant micronutrients in cancer prevention
17. MHC imbalance and metastatic spread in Lewis lung carcinoma clones
18. Vitamin E blocks the cytotoxic effect of gamma linolenic acid when administered as late at the time of onset cytotoxicity
19. 5-Hydroxymethyluracil excretion, plasma TBARS and plasma antioxidant vitamins in Adriamycin-treated patients
20. Effect of dietary menhaden oil on tumor cell loss and accumulation of mass of a transportable mammary adenocarcinoma in Balb/c mice
21. Superoxide radicals and lipid peroxidation in tumor microsomal membranes
22. Dietary n-3 polyunsaturated fatty acids and oxidants increase rat mammary tumor sensitivity to epirubicin without change in cardiac toxicity
23. Insulin and colon cancer
24. Effects of iron supplementation and ET-18-OCH3 on MDA-MB 231 breast carcinomas in nude mice consuming a fish oil diet
25. Fish oil supplementation enhanced CPT11 (isomotecan) efficiency against MCF7 breast carcinoma xenografts and ameliorated intestinal side effects
26. Antioxidant vitamins and cancer
27. Effect of dietary linoleic acid level on lodgment, proliferation and survival of mammary tumor metastases
28. Omega-3 fatty acids in cancer, a review
29. Effects of omega-3 fatty acids on growth of a rat mammary tumor
30. Diets induced changes in plasma membrane fatty acid composition, affect physical proportions, detected with a spin label probe
31. Omega-3 fatty acids inhibiting the growth of a transplantable rat mammary adenocarcinoma
32. The protein thiolmetallothionein as an antioxidant and protectant against antineoplastic drugs
33. Growth of human lung carcinoma in nude mice influenced by various types of dietary fat and vitamin E
34. High dietary omega-6 polyunsaturated fatty acid drastically increase the formation of etheno-DNA base adducts in white blood cells of female subjects
35. Inhibitory effect of esculetin on 5 lipoxygenase and leukotriene biosynthesis
36. Detection of lipid radicals by electron paramagnetic resonance spin trapping using intact cells enriched with polyunsaturated fatty acids
37. Dietary fatty acids. The n-6/n-3 balance and chronic elderly diseases. Excess linolenic acid and relative n-3 deficiency syndrome seen in Japan
38. Benefits and liabilities of vitamin A and carotenoids
39. Modification of the effect of tamoxifen, cis-platin, DTIC, and interferon-alpha 2b on human melanoma cells in culture by a mixture of vitamins
40. Effect of different levels of dietary trans fat on corn oil on azoxymethane-induced colon carcinogenesis in F 344 rats
41. Promotion by unsaturated fat of azaserine-induced pancreatic carcinogenesis in the rat
42. The effect of chemotherapeutic drugs on free radical oxidation of lipids in the lymph of lung patients
43. Cytotoxic effects of free fatty acids on ascites tumor cells
44. Inhibitory effect of a primary tumor on metastasis
45. Whole-body hyperthermia and lonidamine as adjuvant therapy to treatment with cisplatin with or without local radiation in mouse bearing the Lewis lung carcinoma
46. Bleomycin-induced pulmonary fibrosis following chemotherapy of ovarian granulosa cell tumor
47. Experimental evaluation of combination chemotherapy with UFT and cisplatin for lung cancer
48. Normal tissue protection in cancer therapy - Progress and prospects
49. Polyunsaturated fatty acids increase the sensitivity of 36B10 rat astrocytoma cells to radiation-induced cell kill
50. Dietary fat intake and risk of lung cancer: A prospective study of 51,452 Norwegian men and women
51. Insulin-cancer relationships. Possible dietary implications
52. Insulin and glucose status, tissue and plasma lipids in patients with tumours of the ovary or endometrium: Possible dietary implications
53. Dietary fish oil suppresses tumor growth and metastasis of Lewis lung carcinoma in mice