Pharmacologic modulators of nitric oxide exacerbate tubulointerstitial inflammation in proteinuric rats

Journal of the American Society of Nephrology

Volumn 12, Issue 8, 2001, Pages 1696-1705

  Rangan, G K ^a   Wang, Y ^a   Harris, D C H ^a  

^a FREMANTLE HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGUANIDINE; ARGININE; CREATININE; CYTOKINE; DOXORUBICIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LYSINE DERIVATIVE; MALONALDEHYDE; MOLSIDOMINE; MONOCYTE CHEMOTACTIC PROTEIN 1; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; CREATININE CLEARANCE; CYTOKINE PRODUCTION; DISEASE COURSE; INTERSTITIAL NEPHRITIS; MALE; MONOCYTE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEINURIA; RAT;

EID: 0034923880     PISSN: 10466673     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (46)

1. Physiology and pathophysiology of nitric oxide in chronic renal disease
2. From rats to man: A perspective on dietary L-arginine supplementation in human renal disease
3. Exhaled nitric oxide (NO), NO synthase activity, and regulation of NF-κB
4. New insights into the role of NF-κB, a ubiquitous transcription factor in the initiation of diseases
5. Dependence and reversal of nitric oxide production on NF-κB in silica and lipopolysaccharide-induced macrophages
6. Inhibition of endothelial vascular cell adhesion molecule-1 expression by nitric oxide involves the induction and nuclear translocation of IκBα
7. Nitric oxide attenuates vascular smooth muscle cell activation by IFN-γ. The role of constitutive NF-κB activity
8. Dual effect of nitric oxide donors on cyclooxygenase-2 expression in human mesangial cells
9. A molecular redox switch on p21(ras). Structural basis for the nitric oxide-p21(ras) interactions
10. Activation of NF-κB by nitric oxide in rat striatal neurones: Differential inhibition of the p50 and p65 subunits by dexamethasone
11. Nitric oxide up-regulates the expression of intercellular adhesion molecule-1 on cancer cells
12. Nitric oxide regulates monocyte chemotactic protein-1
13. NF-κB induction during in vivo hypoxia in dorsocaudal brain stem of rat: Effect of MK801 and L-NAME
14. Tubulointerstitial changes as a major determinant in the progression of renal damage
15. ACE inhibition while reducing proteinuria also suppresses NF-κB activation and reduces renal MCP-1 in rats with remnant kidney
16. Overload proteinuria elicits nuclear factor κB activation in tubular epithelial cells: Role of angiotensin II and endothelin-1
17. Inhibition of NF-κB activation reduces cortical tubulointerstitial injury in proteinuric rats
18. Arginine administration blunts activation of nuclear factor κB in the kidney of rats with ureteral obstruction
19. L-arginine suppresses lipopolysaccharide-induced expression of RANTES in glomeruli
20. L-arginine decreases the infiltration of the kidney by macrophages in obstructive nephropathy and puromycin-induced nephrosis
21. Oral administration of L-arginine and captopril in rats prevents chronic renal failure by nitric oxide production
22. Renoprotection by nitric oxide donor and lisinopril in the remnant kidney model
23. Chronic aminoguanidine attenuates renal dysfunction and injury in aging rats
24. Inhibition of inducible nitric oxide synthase intensifies injury and functional deterioration in autoimmune interstitial nephritis
25. Stereologic methods and their application in kidney research
26. Cytokine gene expression in adriamycin nephropathy: Effects of antioxidant NF-κB inhibitors in established disease
27. Role of nitric oxide in rat nephrotoxic nephritis: Comparison between inducible and constitutive nitric oxide synthase
28. Exogenous nitric oxide prevents endotoxin-induced glomerular thrombosis in rats
29. Endogenous nitric oxide inhibits human platelet adhesion to vascular endothelium
30. Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells
31. Nitric oxide-mediated apoptosis in murine peritoneal macrophages
32. Role of nitric oxide and phosphodiesterase isoenzyme II for reduction of endothelial hyperpermeability
33. Cytoprotective function of nitric oxide: Inactivation of superoxide radicals produced by human leukocytes
34. Biological effects of aminoguanidine: An update
35. The role of NO and apoptosis in ADR induced nephrosis: The effect of iNOS inhibition
36. Metabolic fate of 5-ethoxycarbonyl-3-morpholinosydnonimine (SIN-10). 1. Absorption, excretion and tissue distribution in rats and mice
37. Aortic endothelial cells damaged by a nitric oxide donor and protected by flavonoids
38. Effect of nitric oxide donors on renal tubular epithelial cell-matrix adhesion
39. Protection by taurine against adriamycin-induced proteinuria and hyperlipidemia in rats
40. Evidence suggesting that nitric oxide mediates iron-induced toxicity in cultured proximal tubule cells
41. Achieving transcriptional specificity with NF-κB
42. Randomized, double-blind, placebo-controlled study of arginine supplementation in chronic renal failure
43. Pregnancy-induced hypertension in rats with adriamycin nephropathy is associated with an inadequate production of nitric oxide
44. Osteopontin inhibits induction of nitric oxide synthase gene expression by inflammatory mediators in mouse kidney epithelial cells
45. Nephrosis augments contractile response to adrenoceptor agonists by the decrease in release of endothelium-derived relaxing factor from the endothelial cells
46. NF-κB and transcriptional control of renal epithelial-inducible nitric oxide synthase