Pregnancy-induced hypertension in rats with adriamycin nephropathy is associated with an inadequate production of nitric oxide

Hypertension

Volumn 29, Issue 4, 1997, Pages 986-991

  Podjarny, Eduardo ^b   Ben Chetrit, Sidney ^b   Rathaus, Mauro ^b   Korzets, Zeev ^b   Green, Janice ^b   Katz, Bernard ^b   Bernheim, Jacques ^a  

^a MEIR MEDICAL CENTER   (Israel)

^b NONE

Author keywords

doxorubicin; nitric oxide; pregnancy; rats

Indexed keywords

ARGININE; CREATININE; DOXORUBICIN; NITRIC OXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CREATININE CLEARANCE; FEMALE; GLOMERULUS FILTRATION RATE; KIDNEY DISEASE; MATERNAL HYPERTENSION; MEAN ARTERIAL PRESSURE; NONHUMAN; PREECLAMPSIA; PRIORITY JOURNAL; PROTEIN URINE LEVEL; PROTEINURIA; RAT; SYSTOLIC BLOOD PRESSURE; VASODILATATION;

EID: 0030951415     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.29.4.986     Document Type: Article

References (22)

1. Abe S. An overview of pregnancy in women with underlying renal disease. Am J Kidney Dis. 1991;17:112-115.
2. Baylis C, Engels K. Adverse interactions between pregnancy and a new model of systemic hypertension produced by chronic blockade of endothelial derived relaxing factor (EDRF) in the rat. Clin Exp Hypertens Preg. 1992;B11:117-119.
3. Henessy A, Gillin AG, Phippard AF, Duggin GG, Horvarth JS, Tiller DJ. The role of endothelin and ERDF (nitric oxide) in the control of the circulation in primate pregnancy. In: Proceedings from IXth International Congress of the International Society for the Study of Hypertension in Pregnancy; 1994:64. Abstract.
4. Podjarny E, Bernheim JL, Rathaus M, Pomeranz A, Tobvin D, Shapira J, Bernheim J. Adriamycin nephropathy: a model to study the effects of pregnancy on renal disease in rat. Am J Physiol. 1992;263:F711-F715.
5. Konings CH. A kinetic procedure for estimation of arginine in serum using arginine-kinase. Clin Chim Acta. 1988;176:185-194.
6. Pomeranz M, Podjarny E, Bernheim JL, Pomeranz A, Rathaus M, Green J, Bernheim J. Effect of recurrent pregnancies on the evolution of adriamycin nephropathy. Nephrol Dial Transplant. 1995; 10:2049-2053.
7. Podjarny E, Pomeranz A, Rathaus M, Green J, Gonen O, Shamir R, Bernheim J. Effect of L-arginine treatment in pregnant rats with adriamycin nephropathy. Hypertension in Pregnancy. 1993;12: 517-524.
8. Henry JB. Clinical Diagnosis and Management by Laboratory Methods. 17th ed. Philadelphia, Pa: WB Saunders Co; 1984: 405-410.
9. Gilliam MB, Sherman MP, Griscavage JM, Ignarro LJ. A spectrophotometric assay for nitrate using NADPH oxidation by Aspergillus reductase. Anal Biochem. 1993;212:359-365.
10. Danielson LA, Conrad KP. Acute blockade of nitric oxide synthase inhibits renal vasodilation and hyperfiltration during pregnancy in chronically instrumented conscious rats. J Clin Invest. 1995;96: 482-490.
11. Conrad KP, Joffe GM, Kruszina H, Kruszina R, Rochelle LG, Smith RP, Chavez JE, Mosher MD. Identification of increased nitric oxide biosynthesis during pregnancy in rats. FASEB J. 1993; 7:566-571.
12. Cameron IT, Van Papendorp CL, Palmer RMJ, Smith SK, Moncada S. Relationship between nitric oxide synthesis and increase in systolic blood pressure in women with hypertension in pregnancy. Hypertension in Pregnancy. 1993;12:85-92.
13. Brown M, Tibben E, Zammit VC, Cario G, Carlton M. Nitric oxide excretion in normal and hypertensive rats. Hypertension in Pregnancy. 1993;14:319-326.
14. Doerr RC, Fox JB Jr, Lakritz L, Fiddler W. Determination of nitrite in cured meats by chemiluminescence detection. Anal Chem. 1981;53:381-384.
15. Baylis C. Glomerular filtration and volume regulation in gravid animal models. In: Lindheimer MD, Davison JM, eds. Baillieres Obstetrics and Gynecology. 2nd ed. London, UK: Bailliere Tindal; 1994;8:235-264.
16. McCarthy AL, Woolfson RG, Raju SK, Poston L. Abnormal endothelial cell function in resistance arteries from women with preeclampsia. Am J Obstet Gynecol. 1993;168:1323-1330.
17. Debelder AJ, Lees C, Martin J, Moncada S, Campbell S. Treatment of HELLP syndrome with nitric oxide donor. Lancet. 1995;345: 124-125.
18. Baylis C, Deng A, Couser W. Glomerular hemodynamics effect of late pregnancy in rats with experimental membranous nephropathy. J Am Soc Nephrol. 1995;6:1997-2201.
19. Domenench M, Gruppuso PA, Nishino VT, Susa JB, Schwartz R. Preserved fetal plasma aminoacid concentration in presence of maternal hypoaminoacidemia. Pediatr Res. 1986;20:1071-1076.
20. Rathaus M, Podjarny E, Green J, Bernheim J. Role of nitric oxide in the exaggerated vasoconstrictory response to noradrenaline induced by low dose adriamycin in the mesenteric bed of pregnant rats. J Am Soc Nephrol. 1995;6:668. Abstract.
21. Weiner CP, Lizasoain I, Baylis SA, Knowles RG, Charles G, Moncada S. Induction of calcium-dependent nitric oxide synthase by sex hormones. Proc Natl Acad Sci U S A. 1994;91:5212-5216.
22. Raij L. Glomerular thrombosis in pregnancy: role of the L-arginine-nitric oxide pathway. Kidney Int. 1994;45:775-781.