Non-invasive methods for absolute cerebral blood flow measurement using 99mTc-ECD: A study in healthy volunteers

European Journal of Nuclear Medicine

Volumn 28, Issue 7, 2001, Pages 862-872

  Van Laere, Koenraad ^a   Dumont, Filip ^b   Koole, Michel ^b   Dierckx, Rudi ^a  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

^b GHENT UNIVERSITY   (Belgium)

Author keywords

Brain perfusion index; Graphical analysis; Octanol extraction; Spectral analysis; Technetium 99m ethyl cysteinate dimer

Indexed keywords

CYSTEINE ETHYL ESTER TC 99M; OCTANOL;

ADULT; AGED; ARTICLE; BRAIN; BRAIN BLOOD FLOW; BRAIN PERFUSION; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; SCINTIANGIOGRAPHY; SPECTROSCOPY;

ADULT; AGED; AGED, 80 AND OVER; AGING; CEREBROVASCULAR CIRCULATION; CROSS-SECTIONAL STUDIES; CYSTEINE; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MALE; MIDDLE AGED; ORGANOTECHNETIUM COMPOUNDS; PROSPECTIVE STUDIES; RADIONUCLIDE ANGIOGRAPHY; RADIOPHARMACEUTICALS; REFERENCE VALUES; SEX CHARACTERISTICS; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 0034918716     PISSN: 03406997     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002590100559     Document Type: Article

References (59)

1. Mapping the ischaemic penumbra with PET: A new approach
2. Voxel-based mapping of irreversible ischaemic damage with PET in acute stroke
3. Early Tc-99m-ethylcysteinate dimer brain SPECT patterns in the acute phase of stroke as predictors of neurological recovery
4. Longitudinal evaluation of early Alzheimer's disease using brain perfusion SPECT
5. PET measurements of brain glucose metabolism and blood flow in major depressive disorder: A critical review
6. Quantitative mapping of regional cerebral blood flow using iodine-123-IMP and SPECT
7. Quantification of regional cerebral blood flow with continuous infusion of technetium-99m-ethyl cysteinate dimer
8. 123I]-iodoamphetamine and single-photon emission computed tomography
9. A comparative study of simple methods to measure regional cerebral blood flow using iodine-123-IMP SPECT
10. 99mTc-ECD SPECT and continuous arterial blood sampling
11. Quantitative measurement of regional cerebral blood flow using N-isopropyl-(iodine-123)p-iodoamphetamine and single-photon emission computed tomography
12. A quantitative approach to technetium-99m hexamethylpropylene amine oxime
13. Non-invasive measurements of regional cerebral blood flow using technetium-99m hexamethylpropylene amine oxime
14. A quantitative approach to technetium-99m ethyl cysteinate dimer: A comparison with technetium-99m hexamethylpropyleneamine oxime
15. Noninvasive quantitation of cerebral blood flow using oxygen-15-water and a dual-PET system
16. 99mTc-ECD using the aortic activity as arterial input estimate
17. Effect of deadtime loss on quantitative measurement of cerebral blood flow with technetium-99m hexamethylpropylene amine oxime
18. Spectral analysis of dynamic PET studies
19. Which linear compartmental systems can be analyzed by spectral analysis of PET output data summed over all compartments?
20. Pharmacokinetic assessment of novel anti-cancer drugs using spectral analysis and positron emission tomography: A feasibility study
21. 18F]fluorodeoxyglucose: Theory, implementation, and optimization procedures
22. 18F]FDG kinetics for heart and brain studies with PET
23. An alternative approach to estimation of the brain perfusion index for measurement of cerebral blood flow using technetium-99m compounds
24. 123I]-iodoamphetamine SPECT
25. Evaluation of cerebral blood flow in patients with idiopathic orthostatic hypotension using Tc-99m HMPAO brain SPECT during postural testing
26. Cerebral blood flow measurement with iodine-123-IMP SPECT, calibrated standard input function and venous blood sampling
27. 99mTc-ECD and SPECT
28. Non-uniform versus uniform attenuation correction in brain perfusion SPET of healthy volunteers
29. 99mTc-ECD brain SPET databases between different gamma cameras
30. Patterns of hand preference in a student population
31. 99mTc-HMPAO]: Basic kinetic studies of a tracer of cerebral blood flow
32. 99mTc-ECD: Measurement of arterial input and brain retention
33. 99mTc]-d,l-HMPAO in the human brain after intracarotid bolus injection: A kinetic analysis
34. Improving the measurement of the Tc-99(m)-ECD brain perfusion index by temporal analysis
35. Regional cerebral blood flow measurement with iodine-123-IMP autoradiography: Normal values, reproducibility and sensitivity to hypoperfusion
36. 15)O-PET
37. 15O-labelled water and dynamic positron emission tomography
38. 18F]-2-fluoro-2-deoxy-D-glucose method in resting, healthy human subjects
39. A correction method for high-count-rate quantitative radionuclide angiography
40. 99mTc-HMPAO SPECT
41. Alterations in regional cerebral blood flow, with increased temporal interhemispheric asymmetries, in the normal elderly: An HMPAO SPECT study
42. Sex differences in regional cerebral blood flow
43. 99mTc-HMPAO study
44. Regional asymmetries of cerebral blood flow, blood volume, and oxygen utilization and extraction in normal subjects
45. Normal patterns on Tc-99m-ECD brain SPECT scans in adults
46. 99mTc-ECD brain perfusion SPET: Variability, asymmetry and effects of age and gender in healthy adults
47. Sex differences in patterns of hemispheric cerebral metabolism: A multiple regression/discriminant analysis of positron emission tomographic data
48. Sex differences in regional glucose metabolism during the resting state
49. Sex differences in human brain morphometry and metabolism: An in vivo quantitative magnetic resonance imaging and positron emission tomography study on the effect of aging
50. The metabolic topography of normal aging
51. MRI of the normal brain from early childhood to middle age. I. Appearances on T2- and proton density-weighted images and occurrence of incidental high-signal foci
52. Age-related changes in intracranial compartment volumes in normal adults assessed by magnetic resonance imaging
53. Normal and pathological aging-findings of positron-emission-tomography
54. Human aging
55. Effects of healthy aging on the regional cerebral metabolic rate of glucose assessed with statistical parametric mapping
56. The metabolic topography of normal aging
57. Changes in cerebral glucose metabolism with normal aging
58. Does cerebral blood flow decline in healthy aging? A PET study with partial-volume correction
59. Age and gender effects in brain perfusion SPECT correlated to voxel-based morphometry in healthy adults