Tumor necrosis factor: Genetics, cellular mechanism of action and its implication in inflammation;Factor de necrosis tumoral. Genética, mecanismo de acción celular y su implicación en la inflamación

Alergologia e Inmunologia Clinica

Volumn 16, Issue 3, 2001, Pages 140-150

  Liz Grana M ^a   Gomez Reino Carnota J J ^a  

^a Instituto de Salud Carlos III   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

TUMOR NECROSIS FACTOR;

CELLULAR IMMUNITY; GENE DUPLICATION; GENETICS; INFLAMMATION; MACROPHAGE ACTIVATION; MAJOR HISTOCOMPATIBILITY COMPLEX; REVIEW;

EID: 0034917519     PISSN: 1575734X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (43)

1. Proinflammatory cytokines
2. Molecular cloning of the complementary DNA for human tumor necrosis factor
3. Human tumor necrosis factor-a gene 3′ untranslated region confers inducible toxin responsiveness to homologous promoter in monocytic THP-1 cells
4. Cytokine gene polymorphism in human disease: On-line database
5. Tumor necrosis factor gene polymorphisms as severity markers in rheumatoid arthritis
6. Effects of a polymorphism in the human tumor necrosis factor α promoter on transcriptional activation
7. Primary association of tumor necrosis factor-region genetic markers with susceptibility to rheumatoid arthritis
8. Recent advances in the molecular basis of TNF signal transduction
9. Structure of the human TNF receptor 1 (p60) gene (TNFR1) and localization to cromosome 12p13
10. Human Tumor necrosis factor receptor p75/80 (CD 120b) gene structure and promoter characterization
11. NCBI UniGene Database
12. Structural basis for self-association and receptor recognition of human TRAF2
13. Activation of stress-activated protein kinase/c-Jun N-terminal kinase, but not NF-κB, by the tumor necrosis factor (TNF) receptor 1 through a TNF receptor-associated factor 2 and germinal center kinase related-dependent pathway
14. Tolerance and autoinmunity
15. Anti-tumor necrosis factor specific antibody (infliximab) treatment provides insights into the pathophysiology of reumatoid artritis
16. The function of tumour necrosis factor and receptors in models of multi-organ inflammation, rheumatoid arthritis, multiple sclerosis and inflammatory bowel disease
17. Role of tumour necrosis factor a in experimental arthritis: Separate activity of interleukin 1b in chronicity and cartilage destruction
18. Angioneurotic edema attributed to the use of Losartan
19. The effectiveness of a history-based diagnostic approach in chronic urticaria and angioedema
20. Allergy
21. The promoter of the C1 inhibitor gene contains a polypurine-polypirimidine segment that enhances transcriptional activity
22. Regulation of C1 inhibitor synthesis
23. Cytokines and allergic diseases: Clinical aspects
24. The cellular and mediator basis of asthma in relation to naturla history
25. CbI phosphorylation in human airway smooth muscle cells
26. The role of eosinophils and neutrophils in inflammation
27. Prevalence of tumor necrosis factor-α and angiotensin converting enzyme polymorphisms in mild/moderate and fatal/near-fatal asthma
28. Polymorphisms of the IL-4, TNFα and FcεRIβ genes and the risk of allergic disorders in at-risk infants
29. Inducible expression of a Th2-Type CC chemokine thymus- and activation regulated chemokine by human bronchial epithelial cells
30. TNF-alpha dysregulation in asthma: Relationship to ongoing corticosteroidtherapy
31. Genetics of asthma
32. The genetic basis for periodic fever
33. Cytokine activation during attacks of the hiperimmunoglobulinemia D and periodic fever syndrome
34. Immunoglobulin D enhances the release of tumour necrosis factor-a and interleukin-1b as well as interleukin-1 receptor antagonist from human mononuclear cells
35. The gene for familial mediterranean fever, MEFV, is expressed in early leukocyte development and is regulated in response to inflammatory mediators
36. Germline mutations in the extracellular domains of the 55kDa TNF receptor, TNFR1, defin a family of dominantly inherited autoinflammatory syndromes