The effect of neuroleptic medication on prepulse inhibition in schizophrenia patients: Current status and future issues

Psychopharmacology

Volumn 156, Issue 2-3, 2001, Pages 259-265

  Hamm, A O ^a   Weike, A I ^a   Schupp, H T ^a  

^a UNIVERSITY OF GREIFSWALD   (Germany)

Author keywords

Neuroleptic medication; Prepulse inhibition; Schizophrenia; Startle reflex

Indexed keywords

NEUROLEPTIC AGENT;

ADULT; CALCULATION; CLINICAL ARTICLE; CONTROLLED STUDY; ELECTRIC ACTIVITY; EYELID REFLEX; HUMAN; LONGITUDINAL STUDY; META ANALYSIS; NEUROBIOLOGY; PREPULSE INHIBITION; PRIORITY JOURNAL; REVIEW; SCHIZOPHRENIA; STARTLE REFLEX; STATISTICAL ANALYSIS;

ANTIPSYCHOTIC AGENTS; HUMANS; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY; STARTLE REACTION;

EID: 0034915502     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002130100827     Document Type: Review

References (42)

1. In the blink of an eye: Implications of reflex modification for information processing
2. Clozapine antagonizes phencyclidine-induced deficits in sensorimotor gating of the startle response
3. Startle elicitation: Stimulus parameters, recording techniques, and quantification
4. Short lead interval startle modification
5. Sensorimotor gating and habituation evoked by electro-cutaneous stimulation in schizophrenia
6. Prestimulus effects on human startle reflex in normals and schizophrenics
7. Gating and habituation of the startle reflex in schizophrenic patients
8. Symptom correlates of prepulse inhibition deficits in male schizophrenic patients
9. Impaired startle prepulse inhibition and habituation in patients with schizotypal personality disorder
10. Modulation of the startle response and startle laterality in relatives of schizophrenic patients and in subjects with schizotypal personality disorder: Evidence of inhibitory deficits
11. Attention and schizophrenia: Impaired modulation of the startle reflex
12. On the clinical and cognitive meaning of impaired sensorimotor gating in schizophrenia
13. The psychological significance of human startle eyeblink modification: A review
14. The more or less startling effects of weak prestimulation
15. Distinguishing among orienting, defense, and startle reflexes
16. Attention: The heartbeat, the blink, and the brain
17. Startle gating deficits occur across prepulse intensities in schizophrenic patients
18. Prefrontal cortex glucose metabolism and startle eyeblink modification abnormalities in unmedicated schizophrenia patients
19. Reflex modification in the domain of startle: I. Some empirical findings and their implications for how the nervous system processes sensory input
20. Reflex modification and the analysis of sensory processing in developmental and comparative research
21. Modification of the startle reflex in the rat by changes in the auditory and visual environments
22. Preliminary evidence of an association between sensorimotor gating and distractability in psychosis
23. Failure of haloperidol to block the effects of phencyclidine and dizocilpine on prepulse inhibition in startle
24. The neurobiology of startle
25. The acoustic startle response in rats: Circuits mediating evocation, inhibition and potentiation
26. Normalization of information processing deficits in schizophrenia with clozapine
27. Prepulse inhibition of the startle response in men with schizophrenia: Effects of age of onset of illness, symptoms, and medication
28. Dopaminergic stimulation disrupts sensorimotor gating in the rat
29. Sensory gating and inhibitory function in late-life schizophrenia
30. Impaired prepulse inhibition of acoustic startle in schizophrenia
31. Information-processing deficits and thought disorder in schizophrenia
32. Sensorimotor gating and thought disturbance measured in close temporal proximity in schizophrenic patients
33. Preconditioning and excitability of the human orbucularis oculi reflex as a function of state
34. Reflex modification in psychosisprone young adults
35. Using an animal model of deficient sensorimotor gating to study the pathophysiology and new treatments of schizophrenia
36. Effects of spiperone, raclopride, SCH 23390, and clozapine on apomorphine inhibition of sensorimotor gating of the startle response in the rat
37. Men are more inhibited than women by weak prepulses
38. Assessing the validity of an animal model of deficient sensory gating in schizophrenic patients
39. "Normal" personality correlates of sensorimotor, cognitive, and visuo-spatial gating
40. Changes in sensorimotor gating across the menstrual cycle: Implications for neuropsychiatric disorders
41. Animal models of deficient sensorimotor gating: What we know, what we think we know, and what we hope to know soon
42. Effective neuroleptic medication removes prepulse inhibition deficits in schizophrenia patients