Combinatorial lead discovery and optimization of antimicrobial oxazolidinones

Current Opinion in Drug Discovery and Development

Volumn 4, Issue 4, 2001, Pages 450-461

  Gordeev, M F ^a  

^a Versicor Inc   (United States)

Author keywords

Combinatorial chemistry; Oxazolidinone; Pharmacophore

Indexed keywords

AMOXICILLIN PLUS CLAVULANIC ACID; ANTIINFECTIVE AGENT; DALFOPRISTIN PLUS QUINUPRISTIN; LINEZOLID; N [[3 (4 ACETYLPHENYL) 2 OXO 5 OXAZOLIDINYL]METHYL]ACETAMIDE; N [[3 [4 (METHYLSULFINYL)PHENYL] 2 OXO 5 OXAZOLIDINYL]METHYL]ACETAMIDE; OXAZOLIDINONE DERIVATIVE;

ANTIBIOTIC RESISTANCE; ANTIMICROBIAL ACTIVITY; CLINICAL TRIAL; DRUG ACTIVITY; DRUG APPROVAL; DRUG MECHANISM; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; GRAM NEGATIVE INFECTION; HUMAN; METHODOLOGY; NONHUMAN; PROTEIN SYNTHESIS INHIBITION; REVIEW; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTI-INFECTIVE AGENTS; COMBINATORIAL CHEMISTRY TECHNIQUES; DRUG RESISTANCE, MICROBIAL; HUMANS; OXAZOLIDINONES; PROTEIN SYNTHESIS INHIBITORS;

EID: 0034911229     PISSN: 13676733     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

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