Partial liquid ventilation improves lung function in ventilation-induced lung injury

European Respiratory Journal

Volumn 18, Issue 1, 2001, Pages 93-99

  Vazquez de Anda, G F ^a   Lachmann, R A ^a   Verbrugge, S J C ^a   Gommers, D ^a   Haitsma, J J ^a   Lachmann, B ^a  

^a ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

Author keywords

Mechanical ventilation; Partial liquid ventilation; Ventilation induced lung injury

Indexed keywords

CARBON DIOXIDE; FLUOROCARBON; LUNG SURFACTANT; OXYGEN; PERFLUOROOCTYL BROMIDE; PHOSPHORUS; PROTEIN;

ADULT; AIRWAY PRESSURE; ANIMAL MODEL; ARTERIAL CARBON DIOXIDE TENSION; ARTERIAL OXYGEN TENSION; ARTICLE; ARTIFICIAL VENTILATION; BLOOD GAS; CLINICAL OBSERVATION; CONTROLLED STUDY; DEATH; GAS EXCHANGE; INSPIRATORY CAPACITY; LIQUID VENTILATION; LUNG ALVEOLUS PROTEINOSIS; LUNG FUNCTION; LUNG INJURY; LUNG MECHANICS; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; POSITIVE END EXPIRATORY PRESSURE; PRESSURE VOLUME CURVE; PRIORITY JOURNAL; PROTEIN AGGREGATION; RANDOMIZATION; RAT; RESPIRATORY CARE; STANDARD; SURFACE TENSION;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; FLUOROCARBONS; INTERMITTENT POSITIVE-PRESSURE VENTILATION; LIQUID VENTILATION; LUNG VOLUME MEASUREMENTS; MALE; POSITIVE-PRESSURE RESPIRATION; PULMONARY ALVEOLAR PROTEINOSIS; PULMONARY GAS EXCHANGE; RATS; RATS, SPRAGUE-DAWLEY; RESPIRATORY MECHANICS; WORK OF BREATHING;

EID: 0034910072     PISSN: 09031936     EISSN: None     Source Type: Journal    
DOI: 10.1183/09031936.01.00019901     Document Type: Article

References (29)

1. Mechanisms of ventilation-induced lung injury and its prevention: Role of surfactant
2. Experimental pulmonary oedema due to high intermittent positive pressure ventilation with high inflation pressures. Protection by positive end expiratory pressure
3. Intermittent positive pressure hyperventilation with high inflation pressures produces pulmonary microvascular injury in rats
4. High inflation pressure pulmonary oedema: Respective effects of high airway pressure, high tidal volume, and positive end expiratory pressure
5. Effect of ventilation on movement of surfactant in airways
6. Ventilation strategies affect surfactant aggregate conversion in acute lung injury
7. Effects of ventilation on the efficacy of exogenous surfactant therapy in a rabbit model of acute lung injury
8. Surfactant impairment after mechanical ventilation with large alveolar surface area changes and effects of positive end-expiratory pressure
9. Exogenous surfactant preserves lung function and reduces alveolar Evans blue dye influx in a rat model of ventilation-induced lung injury
10. Intratracheal perfluorocarbon administration as an aid in the ventilatory management of respiratory distress syndrome
11. Intratracheal perfluoracarbon administration combined with artificial ventilation in experimental respiratory distress syndrome: Dose dependent improvement of gas exchange
12. Evaluation of gas exchange, pulmonary compliance, and lung injury during total and partial liquid ventilation in the acute respiratory distress syndrome
13. Partial liquid ventilation
14. Positive end-expiratory pressure improves gas exchange and pulmonary mechanics during partial liquid ventilation
15. Computer tomographic assessment of perfluorocarbon and gas distribution during partial liquid ventilation for acute respiratory failure
16. Ventilator induced lung injury. Lessons from experimental studies
17. Partial liquid ventilation improves gas exchange and increases EELV in acute lung injury
18. Exogenous surfactant therapy increases static lung compliance, and cannot be assessed by measurements of dynamic compliance alone
19. In vivo lung lavage as an experimental model of the respiratory distress syndrome
20. A numerical index stability of lung expansion
21. Degradation of surfactant associated protein B (SP-B) during in vitro conversion of large into small surfactant aggregates
22. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding
23. Prevention of respiratory failure after hydrochloric acid aspiration by intratracheal surfactant instillation in rats
24. A biophysical mechanism by which plasma proteins inhibit surfactant activity
25. Alteration of surfactant function due to protein leakage: Special interaction with fibrin monomer
26. Hyper-inflation-induced lung injury during alveolar flooding in rats. Effect of perfluorocarbon instillation
27. Superimposing positive end-expiratory pressure during partial liquid ventilation in experimental lung injury
28. Comparing the effects of four different perfluorocarbons on gas exchange and lung mechanics in an animal model of acute lung injury
29. Comparison oexogenous surfactant therapy, mechanical ventilation with high end-expiratory pressure and partial liquid ventilation in a model of acute lung injury