Positive end-expiratory pressure improves gas exchange and pulmonary mechanics during partial liquid ventilation

American Journal of Respiratory and Critical Care Medicine

Volumn 158, Issue 5 PART I, 1998, Pages 1550-1556

  Kirmse, Max ^a   Fujino, Yuji ^a   Hess, Dean ^a   Kacmarek, Robert M ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PERFLUOROOCTYL BROMIDE;

ADULT RESPIRATORY DISTRESS SYNDROME; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ARTIFICIAL VENTILATION; CONTROLLED STUDY; GAS EXCHANGE; LUNG COMPLIANCE; LUNG MECHANICS; NONHUMAN; POSITIVE END EXPIRATORY PRESSURE; PRESSURE VOLUME CURVE; PRIORITY JOURNAL; SHEEP;

ANALYSIS OF VARIANCE; ANIMALS; DISEASE MODELS, ANIMAL; EMULSIONS; FLUOROCARBONS; LUNG COMPLIANCE; OXYGEN; POSITIVE-PRESSURE RESPIRATION; PRESSURE; PULMONARY GAS EXCHANGE; PULMONARY VENTILATION; RANDOM ALLOCATION; RESPIRATORY DEAD SPACE; RESPIRATORY DISTRESS SYNDROME, ADULT; RESPIRATORY MECHANICS; SHEEP; TIDAL VOLUME; VENTILATION-PERFUSION RATIO;

EID: 0031762978     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.158.5.9708100     Document Type: Article

References (28)

1. Gattinoni, L., A. Pesenti, M. Bombino, S. Baglioni, M. Rivolta, F. Rossi, G. Rossi, R. Fumagalli, R. Marcolin, D. Mascheroni, and A. Torresin. 1988. Relationships between lung computed tomographic density, gas exchange, and PEEP in acute respiratory failure. Anesthesiology 69:824-832.
2. Suter, P. M., B. Fairley, and M. D. Isenberg. 1975. Optimum end-expiratory airway pressure in patients with acute pulmonary failure. N. Engl. J. Med. 292:284-289.
3. Fuhrman, B. P., P. R. Paczan, and M. DeFrancisis. 1991. Perfluorocarbon-associated gas exchange. Crit. Care Med. 19:712-722.
4. Shaffer, T. H., M. R. Wolfson, and L. C. Clark, Jr. 1992. Liquid ventilation. Pediatr. Pulmonol. 14:102-109.
5. Tütüncü, A. S., N. S. Faithfull, and B. Lachmann. 1993. Intratracheal perfluorocarbon administration combined with mechanical ventilation in experimental respiratory distress syndrome: dose-dependent improvement of gas exchange. Crit. Care Med. 21:962-969.
6. Hirschl, R. B., M. C. Overbeck, A. Parent, R. Hernandez, S. Schwartz, A. Dosanjh, K. Johnson, and R. H. Bartlett. 1994. Liquid ventilation provides uniform distribution of perfluorocarbon in the setting of respiratory failure. Surgery 116:159-167.
7. Hurst, J. M., and R. D. Branson. 1996. Liquid breathing - partial liquid ventilation. Respir. Care 41:416-423.
8. Hernan, L. J., B. P. Fuhrman, R. E. Kaiser, S. Penfil, C. Foley, M. C. Papo, and C. L. Leach. 1996. Perfluorocarbon-associated gas exchange in normal and acid-injured large sheep. Crit. Care Med. 24:475-481.
9. Gattinoni, L., A. Pesenti, L. Avalli, F. Rossi, and M. Bombino. 1987. Pressure-volume curve of total respiratory system in acute respiratory failure. Computed tomographic scan study. Am. Rev. Respir. Dis. 136:730-736.
10. Amato, M. B., C. S. Barbas, D. M. Medeiros, G. Schettino, G. Lorenzi Filho, R. A. Kairalla, D. Deheinzelin, C. Morais, E. D. Fernandes, T. Y. Takagaki, and C. R. R. de Carvalho. 1995. Beneficial effects of the "open lung approach" with low distending pressures in acute respiratory distress syndrome: a prospective randomized study on mechanical ventilation. Am. J. Respir. Crit. Care Med. 152:1835-1846.
11. Lachmann, B., B. Robertson, and J. Vogel. 1980. In vivo lung lavage as an experimental model of the respiratory distress syndrome. Acta Anaesthesiol. Stand. 24:231-236.
12. Mang, H., R. M. Kacmarek, R. Ritz, R. S. Wilson, and W. P. Kimball. 1995. Cardiorespiratory effects of volume- and pressure-controlled ventilation at various I/E ratios in an acute lung injury model. Am. J. Respir. Crit. Care Med. 151:731-736.
13. Beydon, L., and F. Lemaire. 1991. Lung mechanics in ARDS: compliance and pressure-volume curves. In W. M. Zapol and F. Lemaire, editors. Adult Respiratory Distress Syndrome. Marcel Dekker, New York. 139-161.
14. Nunn, J. F. 1993. Distribution of pulmonary ventilation and perfusion. In Nunn's Applied Respiratory Physiology, 3rd ed. Butterworth-Heinemann Ltd., Oxford. 156-197.
15. Tütüncü, A. S., N. S. Faithfull, and B. Lachmann. 1993. Comparison of ventilatory support with intratracheal perfluorocarbon administration and conventional mechanical ventilation in animals with acute respiratory failure. Am. Rev. Respir. Dis. 148:785-792.
16. Overbeck, M. C., T. Pranikoff, C. M. Yadao, and R. B. Hirschl. 1996. Efficacy of perfluorocarbon partial liquid ventilation in a large animal model of acute respiratory failure. Crit. Care Med. 24:1208-1214.
17. Parent, A. C., M. C. Overbeck, and R. B. Hirschl. 1997. Oxygen dynamics during partial liquid ventilation in a sheep model of severe respiratory failure. Surgery 121:320-327.
18. Curtis, S. E., J. T. Peek, and D. R. Kelly. 1993. Partial liquid breathing with perflubron improves arterial oxygenation in acute canine lung injury. J. Appl. Physiol. 75:2693-2702.
19. Falke, K. J., H. Pontoppidan, A. Kumar, D. E. Leith, G. Geffin, and M. B. Laver. 1972. Ventilation with end-expiratory pressure in acute lung disease. J. Clin. Invest. 51:2315-2323.
20. Hirschl, R. B., R. Tooley, A. Parent, K. Johnson, and R. H. Bartlett. 1996. Evaluation of gas exchange, pulmonary compliance, and lung injury during total and partial liquid ventilation in the acute respiratory distress syndrome. Crit. Care Med. 24:1001-1008.
21. Gattinoni, L., L. D'Andrea, P. Pelosi, G. Vitale, A. Pesenti, and R. Fumagalli. 1993. Regional effects and mechanism of positive end-expiratory pressure in early adult respiratory distress syndrome. J.A.M.A. 269:2122-2127.
22. Barbas, C. S. V., M. B. P. Amato, M. Goldner, A. Adams, R. Shapiro, A. Nahum, and J. J. Marini. 1997. Effect of PEEP on regional pleural pressures (PPL) during partial liquid ventilation (PLV) in dogs with oleic acid (abstract). Am. J. Respir. Crit. Care Med. 155:A86.
23. Kaisers, U., R. Kuhlen, K. Falke, and R. Rossaint. 1997. Positive end-expiratory pressure further improves pulmonary gas exchange during partial liquid ventilation in experimental lung injury (abstract). Am. J. Respir. Crit. Care Med. 155:A950.
24. Lowe, C. A., and T. H. Shaffer. 1986. Pulmonary vascular resistance in the fluorocarbon-filled lung. J. Appl. Physiol. 60:154-159.
25. Dantzker, D. R., C. J. Brook, P. Dehart, J. P. Lynch, and J. G. Weg. 1979. Ventilation-perfusion distributions in the adult respiratory distress syndrome. Am. Rev. Respir. Dis. 120:1039-1052.
26. Leach, C. L., B. P. Fuhrman, F. C. Morin, and M. G. Rath. 1993. Perfluorocarbon-associated gas exchange (partial liquid ventilation) in respiratory distress syndrome: a prospective, randomized, controlled study. Crit. Care Med. 21:1270-1278.
27. Pare, P. D., B. Warriner, E. M. Baile, and J. C. Hogg. 1983. Redistribution of pulmonary extravascular water with positive end-expiratory pressure in canine pulmonary edema. Am. Rev. Respir. Dis. 127:590-593.
28. Grunauer, M. A., M. B. P. Amato, C. S. B. Valente, V. L. Copelozzi, S. K. Kubo, R. S. Poggetti, M. Dolhnikoff, and C. R. R. Carvalho. 1997. The lower inflection point of the static P-V curve (Pflex) may not predict complete alveolar opening in normal lungs (abstract). Am. J. Respir. Crit. Care Med. 155:A505.