Cell-cycle and developmental regulation of TbRAB31 localisation, a GTP- locked Rab protein from Trypanosoma brucei

Molecular and Biochemical Parasitology

Volumn 106, Issue 1, 2000, Pages 21-35

  Field, Helen ^a   Sherwin, Trevor ^b   Smith, Aden C ^c   Gull, Keith ^b   Field, Mark C ^a  

^a WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

Cell cycle; Golgi apparatus; Kinetoplast; Small GTPase; Trypanosoma brucei; Ypt31p

Indexed keywords

CROSS REACTING ANTIBODY; DIAMINOBENZIDINE; GENE PRODUCT; GUANOSINE TRIPHOSPHATASE; PROTOZOAL PROTEIN; RAB PROTEIN;

ARTICLE; CELL CYCLE; CENTRIOLE; ELECTRON MICROSCOPY; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; EXPRESSED SEQUENCE TAG; GENE SEQUENCE; GOLGI COMPLEX; HISTOCHEMISTRY; INTERPHASE; INTRACELLULAR TRANSPORT; KINETOPLAST; MICROTUBULE; MITOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY; TRYPANOSOMA BRUCEI;

ANIMALS; CERAMIDES; DNA, KINETOPLAST; FLUORESCENT ANTIBODY TECHNIQUE; FLUORESCENT DYES; GOLGI APPARATUS; GTP PHOSPHOHYDROLASES; MICROSCOPY, ELECTRON; PROTOZOAN PROTEINS; RAB GTP-BINDING PROTEINS; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY; TRYPANOSOMA BRUCEI BRUCEI;

EID: 0033962667     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(99)00192-9     Document Type: Article

References (46)

1. Cross G.A.M. Glycolipid anchoring of plasma membrane proteins. Annu. Rev. Cell. Biol. 6:1990;1-39.
2. McConville M.J., Ferguson M.A. The structure, biosynthesis and function of glycosylated phosphatidylinositols in the parasitic protozoa and higher eukaryotes. Biochem. J. 294:1993;305-324.
3. Overath P., Stierhof Y., Wiese M. Endocytosis and secretion in trypanosomatid parasites-tumultuous traffic in a pocket. Trends Cell. Biol. 7:1997;27-33.
4. Webster P., Russell D.G. The flagellar pocket of trypanosomatids. Parasitol. Today. 9:1993;201-206.
5. Wang C.C. Molecular mechanisms and therapeutic approaches to the treatment of African trypanosomiasis. Annu. Rev. Pharmacol. Toxicol. 35:1995;93-127.
6. Field M.C., Boothroyd J.C. Trypanosoma brucei: molecular cloning of homologues of small GTP-binding proteins involved in vesicle trafficking. Exp. Parasitol. 81:1995;313-320.
7. Field H., Field M.C. Tandem duplication of Rab genes followed by sequence divergence and acquisition of distinct functions in Trypanosoma brucei. J. Biol. Chem. 272:1997;10498-10505.
8. Nuoffer C., Balch W.E. GTPases: multifunctional molecular switches regulating vesicular traffic. Annu. Rev. Biochem. 63:1994;949-990.
9. Zhang F.L., Casey P. Protein prenylation: molecular mechanisms and functional consequences. Annu. Rev. Biochem. 65:1996;241-269.
10. Lupashin V.V., Waters M.G. t-SNARE activation through transient interaction with a rab-like guanosine triphosphatase. Science. 276:1997;1255-1258.
11. Pfeffer S.R. Transport vesicle docking: SNAREs and associates. Annu. Rev. Cell. Dev. Biol. 12:1996;441-461.
12. Rybin V., Ullrich O., Rubino M., Alexandrov K., Simon I., Seabra M.C., Goody R., Zerial M. GTPase activity of Rab5 acts as a timer for endocytotic membrane fusion. Nature. 383:1996;266-269.
13. Field M.C., Field H., Boothroyd J.C. A homologue of the nuclear GTPase Ran/TC4 from Trypanosoma brucei. Mol. Biochem. Parasitol. 69:1995;131-134.
14. Field H., Farjah M., Pal A., Gull K., Field M.C. Complexity of Trypanosomatid endocytosis pathways revealed by Rab4 and Rab5 isoforms in Trypanosoma brucei. J. Biol. Chem. 273:1998;32102-32110.
15. El-Sayed N.M.A., Alarcon C.M., Beck J.C., Sheffield V.C., Donelson J.E. cDNA expressed sequence tags of Trypanosoma brucei rhodesiense provide new insights into the biology of the parasite. Mol. Biochem. Parasitol. 73:1995;75-90.
16. Field H., Ali B.R.S., Sherwin T., Gull K., Croft S.L., Field M.C. TbRab2p, a marker for the endoplasmic reticulum of Trypanosoma brucei, localises to the ERGIC in mammalian cells. J. Cell. Sci. 112:1999;147-156.
17. Tavitian A., Zahraoui A. Rab proteins and gene family in animals. Methods Enzymol. 219:1992;387-397.
18. Woods A., Sherwin T., Sasse R., MacRae T.H., Baines A.J., Gull K. Definition of individual components within the cytoskeleton of Trypanosoma brucei by a library of monoclonal antibodies. J. Cell. Sci. 93:1989;491-500.
19. Griffiths G., Pepperkok R., Krijnse-Locker J., Kreis T.E. Immunocytochemical localization of β-COP to the ER-Golgi boundary and the TGN. J. Cell. Sci. 108:1995;2839-2856.
20. Sherwin T., Read M. Immunofluorescence of parasites. Methods Mol. Biol. 21:1993;407-414.
21. Sherwin T., Gull K.G. Visualisation of detyrosination along single microtubules reveals novel mechanisms of assembly during cytoskeletal duplication in trypanosomes. Cell. 57:1989;211-221.
22. Wilson A.L., Sheridan K.M., Erdman R.A., Maltese W.A. Prenylation of a Rab1b mutant with altered GTPase activity is impaired in cell free systems but not in intact mammalian cells. Biochem. J. 318:1996;1007-1014.
23. Lai M.H., Bard M., Kirsch D.R. Identification of a gene encoding a new Ypt/Rab-like monomeric G-protein in Saccharomyces cerevisiae. Yeast. 10:1994;399-402.
24. Benli M., Döring F., Robinson D.G., Yang X., Gallwitz D. Two GTPase isoforms, Ypt31p and Ypt32p, are essential for Golgi function in yeast. EMBO J. 15:1996;6460-6475.
25. Chen Y.T., Holcomb C., Moore H.P. Expression and localization of two low molecular weight GTP-binding proteins, Rab8 and Rab10, by epitope tag. Proc. Natl. Acad. Sci. USA. 90:1993;6508-6512.
26. Chen W., Feng Y., Chen D., Wandinger-Ness A. Rab11 is required for trans-Golgi network-to-plasma membrane transport and a preferential target for GDP dissociation inhibitor. Mol. Biol. Cell. 9:1998;3241-3257.
27. Zahraoui A., Joberty G., Arpin M., Fontaine J.J., Tavitian A., Louvard D. A small Rab GTPase is distributed in cytoplasmic vesicles in non polarised cells but colocalises with the tight junction marker ZO-1 in polarised epithelial cells. J. Cell. Biol. 124:1994;101-115.
28. Foster R., Hu K.-Q., Lu Y., Nolan K.M., Thissen J., Settleman J. Identification of a novel human rho protein with unusual properties: GTPase deficiency and in vivo farnesylation. Mol. Cell. Biol. 16:1996;2689-2699.
29. Bangs J.D., Brouch E.M., Ransom D.M., Roggy J.L. A soluble secretory reporter system in Trypanosoma brucei. Studies on endoplasmic reticulum targeting. J. Biol. Chem. 271:1996;18387-18393.
30. Bangs J.D., Ransom D.M., McDowell M.A., Brouch E.M. Expression of bloodstream variant surface glycoproteins in procyclic stage Trypanosoma brucei: role of GPI anchors in secretion. EMBO J. 16:1997;4285-4294.
31. Moore D.R., Smith A., Hager K.M., Walton R., Esko J.D., Hajduk S.L. Developmentally regulated sensitivity of Trypanosoma brucei brucei to the cytotoxic effects of human high-density lipoprotein. Exp. Parasitol. 81:1995;216-226.
32. Matthews K.R., Sherwin T., Gull K. Mitochondrial genome repositioning during the differentiation of the African trypanosome between life cycle forms is microtubule mediated. J. Cell. Sci. 108:1995;2231-2239.
33. Robinson D.R., Gull K. Basal body movements as a mechanism for mitochondrial genome segregation in the trypanosome cell cycle. Nature. 352:1991;731-733.
34. Duden R., Griffiths G., Frank R., Argos P., Kreis T.E. β-COP, a 110 kd protein associated with non-clathrin-coated vesicles and the Golgi shows homology to β-adaptin. Cell. 64:1991;649-665.
35. Denny PW, Gokool S, Russell DG, Field MC, Smith, DF. Trafficking of Leishmania HASPB to the cell surface identifies a novel mechanism of protein export. 1999 submitted for publication.
36. Pagano R.E., Sepanski M.A., Martin O.C. Molecular trapping of a fluorescent ceramide analogue at the Golgi apparatus of fixed cells: interaction with endogenous lipids provides a trans-Golgi marker for both light and electron microscopy. J. Cell. Biol. 109:1989;2067-2079.
37. Novick P., Brennwald P. Friends and family: the role of the Rab GTPases in vesicular traffic. Cell. 75:1993;597-601.
38. Marzesco A.M., Galli T., Louvard D., Zahraoui A. The rod cGMP phosphodiesterase delta subunit dissociates the small GTPase Rab13 from membranes. J. Biol. Chem. 273:1998;22340-22345.
39. Drionich A., Stachelin L.A. The plant Golgi apparatus: structural organization and functional properties. Berger E.G., Roth J. The Golgi Apparatus. 1997;275-301 Birkhäuser, Basel, Switzerland.
40. Ha D., Schwarz J., Turco S., Beverley S. Use of green fluorescent protein as a marker in transfected Leishmania. Mol. Biochem. Parasitol. 77:1996;57-64.
41. Ilgoutz S., Mullin K., Southwell B., McConville M. Glycosylphosphatidylinositol biosynthetic enzymes are localised to a stable tubular subcompartment of the endoplasmic reticulum in Leishmania mexicana. EMBO J. 18:1999;3643-3654.
42. Warren G. Membrane partitioning during cell division. Annu. Rev. Biochem. 62:1993;323-348.
43. Zamze S.E., Ashford D.A., Wooten E.W., Rademacher T.W., Dwek R.A. Structural characterization of the asparagine-linked oligosaccharides from Trypanosoma brucei type II and type III variant surface glycoproteins. J. Biol. Chem. 266:1991;20244-20261.
44. Imboden M., Blum B., DeLange T., Braun R., Seebeck T.h. Tubulin mRNAs of Trypanosoma brucei. J. Mol. Biol. 188:1996;393-402.
45. Affolter M., Rindisbacher L., Braun R. The tubulin gene cluster of Trypanosoma brucei starts with an intact β-gene and ends with a truncated β-gene interrupted by a retrotransposon-like sequence. Gene. 80:1989;177-183.
46. Duszenko M., Seyfang A. Endocytosis and intracellular transport of variant surface glycoproteins in trypanosomes. Adv. Cell. Mol. Biol. Membr. 2:1993;227-258.