Morpholino-induced knockdown of zebrafish engrailed genes eng2 and eng3 reveals redundant and unique functions in midbrain-hindbrain boundary development

Genesis

Volumn 30, Issue 3, 2001, Pages 129-133

  Scholpp, Steffen ^a   Brand, Michael ^a  

^a MAX PLANCK INSTITUTE OF MOLECULAR CELL BIOLOGY AND GENETICS   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; GENE PRODUCT; PROTEIN ENG2; PROTEIN ENG3; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; CONTROLLED STUDY; EMBRYO; GENE EXPRESSION; GENE FUNCTION; KNOCKOUT GENE; MESENCEPHALON; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN LOCALIZATION; RHOMBENCEPHALON; ZEBRA FISH;

ANIMALS; DNA-BINDING PROTEINS; FIBROBLAST GROWTH FACTOR 8; FIBROBLAST GROWTH FACTORS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HOMEODOMAIN PROTEINS; MESENCEPHALON; MICROINJECTIONS; MORPHOGENESIS; MORPHOLINES; NERVE TISSUE PROTEINS; OLIGONUCLEOTIDES, ANTISENSE; PAX2 TRANSCRIPTION FACTOR; PHENOTYPE; RHOMBENCEPHALON; TRANSCRIPTION FACTORS; ZEBRAFISH; ZEBRAFISH PROTEINS;

ANIMALIA; DANIO RERIO; VERTEBRATA;

EID: 0034908357     PISSN: 1526954X     EISSN: None     Source Type: Journal    
DOI: 10.1002/gene.1047     Document Type: Article

References (11)

1. Examining pattern formation in mouse, chicken and frog embryos with an En-specific antiserum
2. Regional expression of three homeobox transcripts in the inner ear of zebrafish embryos
3. A zebrafish engrailed-like homeobox sequence expressed during embryogenesis
4. Preservation of duplicate genes by complementary, degenerative mutations
5. Conservation of engrailed-like homeobox sequences during vertebrate evolution
6. En-1 and En-2, two mouse genes with sequence homology to the Drosophila engrailed gene: Expression during embryogenesis
7. A series of no isthmus (noi) alleles of the zebrafish pax2.1 gene reveals multiple signaling events in development of the midbrain-hindbrain boundary
8. Effective targeted gene 'knockdown' in zebrafish
9. Pax2 and homeodomain proteins cooperatively regulate a 435bp enhancer of the mouse Pax5 gene at the midbrain-hindbrain boundary
10. Vertebrate genome evolution and the zebrafish gene map
11. Two Pax-binding sites are required for early embryonic brain expression of an engrailed-2 transgene