Glucose and insulin modulate the capacity of endothelial cells (HUVEC) to express P-selectin and bind a monocytic cell line (U937)

Thrombosis and Haemostasis

Volumn 86, Issue 2, 2001, Pages 680-685

  Puente Navazo, M D ^a   Chettab, K ^a   Duhault, J ^a   Koenig Berard, E ^a   McGregor, J L ^a  

^a SWISS INST FOR EXP CANCER RESEARCH   (Switzerland)

Author keywords

Endothelial cells; Hyperglycaemia; P selectin

Indexed keywords

CELL ADHESION MOLECULE; GLUCOSE; INSULIN; INTERCELLULAR ADHESION MOLECULE 1; MONOCLONAL ANTIBODY; PADGEM PROTEIN; PADGEM PROTEIN MONOCLONAL ANTIBODY LPY20; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ARTICLE; BLOOD VESSEL INJURY; BLOOD VESSEL WALL; CELL ADHESION; CELL FUNCTION; CELL LINE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE ASSOCIATION; DISEASE COURSE; DRUG ANTAGONISM; ENDOTHELIUM CELL; EXTRAVASATION; HUMAN; HUMAN CELL; HYPERGLYCEMIA; LEUKOCYTE ADHERENCE; MONOCYTE; PREVALENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; REGULATORY MECHANISM; UMBILICAL CORD; VASCULAR DISEASE;

EID: 0034898926     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0037-1616104     Document Type: Article

References (37)

1. Vascular endothelial dysfunction
2. Endothelial cell dysfunction in diabetes mellitus
3. Dysfunction of the endothelial nitric oxide signalling pathway in diabetes and hyperglycaemia
4. Acute hyperglycemia attenuates endothelium-dependent vasodilation in humans in vivo
5. Review of alterations in endothelial nitric oxide production in diabetes: Protective role of arginine on endothelial dysfunction
6. Recents progress in advanced glycation end products and diabetic complications
7. Differential accumulation of advanced glycation end products in the course of diabetic retinopathy
8. What's the RAGE? The receptor for advanced glycation end products (RAGE) and the dark side of glucose
9. Advanced glycosilation endproducts interacting with their endothelial receptor induce the expression of vascular cell adhesion molecule 1 (VCAM-1) in cultured endothelial cells and in mice
10. Upregulation of retinal vascular endothelial growth factor mRNAs in spontaneously diabetic rats without ophthalmoscopic retinopathy: A possible participation of advanced glycation end products in the development of the early phase of diabetic retinopathy
11. Advanced glycosylation end products induced tissue factor expression in human monocyte-like U937 cells and increased tissue factor expression in monocytes from diabetic patients
12. Lipid advanced glycosilation: Pathway for lipid oxidation in vivo
13. Oxidized low-density lipoprotein induces the expression of P-selectin (GMP140/PADGEM/CD62) on human endothelial cells
14. Enhanced expression of intracellular adhesion molecule-1 and P-selectin in the diabetic human retina and choroid
15. Expression of intercellular adhesion molecules (ICAM-1) via an osmotic effect in human umbilical vein endothelial cells exposed to high glucose medium
16. Evidence that glucose increases monocyte binding to human aortic endothelial cells
17. Binding of monocytes from normolipidemic hyperglycaemic patients with type I diabetes to endothelial cells is increased in vitro
18. Elevated levels of circulating adhesion molecules in IDDM patients and in subjects at risk for IDDM
19. Elevated concentrations of circulating adhesion molecules and their association with microvascular complications in insulin-dependent diabetes mellitus
20. The potential role of cell adhesion molecules in the pathogenesis of diabetic neuropathy
21. Inhibition of platelet functions by a monoclonal antibody (LYP20) directed against a granule membrane glycoprotein
22. Identification of a domain (155-183) on CD36 implicated in the phagocytosis of apoptotic neutrophils
23. Isolation and culture of human umbilical vein endothelial cells
24. Activation of 1-arginine transport (system y+) and nitric oxide synthase by elevated glucose and insulin in human endothelial cells
25. Quantification of mRNA by the polymerase chain reaction
26. The tetraspanin CD63/lamp3 cycles between endocytic and secretory compartments in human endothelial cells
27. Elevated circulating P-selectin in insulin-dependent diabetes mellitus
28. Selectin synthesis and inflammation
29. Insulin therapy improves endothelial function in type 2 diabetes
30. Shear stress selectively upregulates intercellular adhesion molecule-1 expression in cultured human vascular endothelial cells
31. Acute hyperglycaemia and oxidative stress generation
32. Insulin's effect on protein kinase C and diacylglycerol induced by diabetes and glucose in vascular tissues
33. Lysophosphatidylcholine promotes P-selectin expression in platelets and endothelial cells. Possible involvement of protein kinase C activation and its inhibition by nitric oxide donors
34. Nitric oxide attenuates adhesion molecule expression in human endothelial cells
35. Glycation, oxidative stress, and scavenger activity: Glucose metabolism and radical scavenger dysfunction in endothelial cells
36. Generation of reactive oxygen intermediates, activation of NF-KappaB and induction of apoptosis in human endothelial cells by glucose. Role of nitric oxide synthase?
37. Oxygen radicals induce human endothelial cells to express GMP-140 and bind neutrophils