A new matrix metalloproteinase inhibitor SI-27 induces apoptosis in several human myeloid leukemia cell lines and enhances sensitivity to TNF alpha-induced apoptosis

Leukemia

Volumn 15, Issue 8, 2001, Pages 1217-1224

  Nakamura, Y ^a   Sato, K ^a   Wakimoto, N ^a   Kimura, F ^a   Okuyama, A ^b   Motoyoshi, K ^a  

^a NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

^b TAIHO PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Apoptosis; Matrix metalloproteinase inhibitor; SI 27; TNF

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; CYTOTOXIC AGENT; DNA; FAS ANTIBODY; FAS LIGAND; I KAPPA B; LIPOCORTIN 5; MATRIX METALLOPROTEINASE INHIBITOR; SI 27; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR; UNCLASSIFIED DRUG;

ACUTE GRANULOCYTIC LEUKEMIA; APOPTOSIS; ARTICLE; CANCER CHEMOTHERAPY; CANCER RECURRENCE; CELL STRAIN HL 60; CELL STRAIN U937; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG SENSITIVITY; DRUG STRUCTURE; ENZYME ACTIVATION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; PRIORITY JOURNAL; PROTEIN DEGRADATION; STAINING;

EID: 0034893479     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2402187     Document Type: Article

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