Multiplex detection of hotspot mutations by rolling circle-enabled universal microarrays

Laboratory Investigation

Volumn 81, Issue 8, 2001, Pages 1079-1086

  Ladner, Daniela P ^a   Leamon, John H ^a   Hamann, Stefan ^a   Tarafa, Gemma ^b   Strugnell, Todd ^a   Dillon, Deborah ^a   Lizardi, Paul ^a   Costa, José ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CATALAN INSTITUTE OF ONCOLOGY   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

OLIGONUCLEOTIDE;

ALLELE; ARTICLE; CANCER DIAGNOSIS; DNA MICROARRAY; DNA PROBE; GENE AMPLIFICATION; HYBRIDIZATION; POINT MUTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SOMATIC MUTATION;

EID: 0034889651     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: 10.1038/labinvest.3780320     Document Type: Article

References (15)

1. Enhanced DNA sequencing by hybridization
2. Detection of steroid 21-hydroxylase alleles using genespecific PCR and a multiplexed ligation detection reaction
3. Fluorescence-based oligonucleotide ligation assay for analysis of cystic fibrosis transmembrane conductance regulator gene mutations
4. Universal DNA microarray method for multiplex detection of low abundance point mutations
5. Detection of heterozygous mutations in BRCA1 using high-density oligonucleotide arrays and two-colour fluorescence analysis
6. Activity of DNA modification and restriction enzymes in KGB, a potassium glutamate buffer
7. Rolling circle amplification of DNA immobilized on solid surfaces and its application to multiplex mutation detection
8. Ligase detection reaction for identification of low abundance mutations
9. Mutational detection and single-molecule counting using rolling-circle amplification
10. Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms
11. A system for specific, high-throughput genotyping by allele-specific primer extension on microarrays
12. Trapped-oligonucleotide incorporation (TONI) assay, a simple method for screening point mutations
13. High throughput parallel analysis of hundreds of patient samples for more than 100 mutations in multiple disease genes
14. Amplification of padlock probes for DNA diagnostics by cascade rolling circle amplification or the polymerase chain reaction
15. Microarray-based detection of select cardiovascular disease markers