Unusual 1H NMR chemical shifts support (His) Cε1-H⋯O=C H-bond: Proposal for reaction-driven ring flip mechanism in serine protease catalysis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 19, 2000, Pages 10371-10376

  Ash, Elissa L ^a   Sudmeier, James L ^a   Day, Regina M ^a   Vincent, Matthew ^a   Torchilin, Ekaterina V ^a   Haddad, Kristin Coffman ^a   Bradshaw, Elizabeth M ^a   Sanford, David G ^a   Bachovchin, William W ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HISTIDINE; MYXOBACTER ALPHA LYTIC PROTEINASE; MYXOBACTER ALPHA-LYTIC PROTEINASE; PROTON; SERINE PROTEINASE; IMIDAZOLE; SUBTILISIN;

ARTICLE; CATALYSIS; CHEMISTRY; CONFORMATION; HYDROGEN BOND; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; COVALENT BOND; CRYSTAL STRUCTURE; ENZYME MECHANISM; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; PROTON TRANSPORT; REACTION ANALYSIS;

CATALYSIS; HISTIDINE; HYDROGEN BONDING; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR CONFORMATION; PROTONS; SERINE ENDOPEPTIDASES;

EID: 0034641613     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.97.19.10371     Document Type: Article

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