Y-chromosome microdeletion and phenotype in cytogenetically normal men with idiopathic azoospermia

Fertility and Sterility

Volumn 76, Issue 3, 2001, Pages 491-495

  Fujisawa, Masato ^a,b   Shirakawa, Toshiro ^a   Kanzaki, Masanori ^a   Okada, Hiroshi ^a   Arakawa, Soichi ^a   Kamidono, Sadao ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NONE   (Japan)

Author keywords

Genetic counseling; Idiopathic azoospermia; Microdeletions; Y chromosome

Indexed keywords

ARTICLE; AZOOSPERMIA; CHROMOSOME DELETION Y; GENETIC COUNSELING; HUMAN; HUMAN CELL; INTRACYTOPLASMIC SPERM INJECTION; MAJOR CLINICAL STUDY; MALE; MALE INFERTILITY; OLIGOSPERMIA; PHENOTYPE; PRIORITY JOURNAL; SERTOLI CELL; Y CHROMOSOME;

ADULT; CHROMOSOME DELETION; CHROMOSOME MAPPING; ESTRADIOL; FOLLICLE STIMULATING HORMONE; HUMANS; LUTEINIZING HORMONE; MALE; OLIGOSPERMIA; PHENOTYPE; PROLACTIN; REFERENCE VALUES; SEMEN; SERTOLI CELLS; SPERMATOGENESIS; TESTIS; TESTOSTERONE; Y CHROMOSOME;

EID: 0034883093     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0015-0282(01)01955-0     Document Type: Article

References (22)

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2. Severe oligospermia resulting from deletions of azoospermia factor gene on Y chromosome
3. Human Y chromosome azoospermia factors (AZF) mapped to different subregions in Yq11
4. Azoospermic men with deletion of the DAZ gene cluster are capable of completing spermatogenesis; fertilizing, normal embryonic development and pregnancy occur when retrieved testicular spermatozoa are used for intracytoplasmic sperm injection
5. Y chromosome deletions in azoospermic and severely oligozoospermic men undergoing intracytoplasmic sperm injection after testicular sperm extraction
6. Localization of factors controlling spermatogenesis in the nonfluorescent portion of the human Y chromosome long arm
7. A Y chromosome gene family with RNA-binding protein homology; candidates for the azoospermic factor AZF controlling human spermatogenesis
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9. Microdeletions of the Y chromosome and intracytoplasmic sperm injection; from gene to clinic
10. The incidence and possible relevance of Y-linked microdeletions in babies born after intracytoplasmic sperm injection and their infertile fathers
11. Men with infertility caused by AZFc deletion can produce sons by intracytoplasmic sperm injection, but are likely to transmit the deletion and infertility
12. The human Y chromosome; a 43-interval map based on naturally occurring deletions
13. Microdeletions of the Y chromosome in Yq11 in idiopathic azoospermia
14. PCR screening for Y chromosome microdeletions; a first step towards the diagnosis of genetically determined spermatogenic failure in men
15. Combined cytogenetic and Y chromosome microdeletion screening in males undergoing intracytoplasmic sperm injection
16. High frequency of well-defined Y-chromosome deletions in idiopathic Sertoli cell-only syndrome
17. Current status of the molecular diagnosis of Y-chromosomal microdeletions in the work up of male fertility
18. Microdeletions within the azoospermia factor subregions of the Y chromosome in patients with idiopathic azoospermia
19. AZFb deletions predict the absence of spermatozoa with testicular sperm extraction; preliminary report of a prognostic genetic test
20. Meiotic cell cycle requirement for a fly homolog of human deleted in azoospermia
21. Deleted in azoospermia (DAZ) genes encode proteins located in human late spermatids and in sperm tails