DAZ (Deleted in AZoospermia) genes encode proteins located in human late spermatids and in sperm tails

Human Reproduction

Volumn 13, Issue 2, 1998, Pages 363-369

  Habermann, B ^a   Mi, H F ^b   Edelmann, A ^b   Bohring, C ^a   Backert I T ^c   Kiesewetter, F ^d   Aumuller G ^a   Vogt, P H ^b,e  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c UNIVERSITY OF TÜBINGEN   (Germany)

^d UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^e NONE   (Germany)

Author keywords

AZFc patients' testis pathology; DAZ gene family; DAZ proteins; Testis specific RNA binding proteins

Indexed keywords

PROTEIN; RNA BINDING PROTEIN;

ARTICLE; AZOOSPERMIA; CHROMOSOME YQ; CYTOPLASM; GENE DELETION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MALE; PROTEIN LOCALIZATION; RNA METABOLISM; SPERMATID; SPERMATOZOON COUNT; SPERMATOZOON MATURATION; SPERMATOZOON TAIL; TESTIS;

EID: 0031913144     PISSN: 02681161     EISSN: None     Source Type: Journal    
DOI: 10.1093/humrep/13.2.363     Document Type: Article

References (27)

1. Ausubel, P.M., Brent, R., Kingston, R.E. et al. (1995) Analysis of proteins. In Current Protocols in Molecular Biology. Vol. 2, John Wiley and Sons, New York, Chapter 10, pp. 1-28.
2. Altschul, S.F., Gish, W., Miller, W. et al. (1990) Basic local alignment search tool. J. Mol. Biol., 215, 403-410.
3. Burd, G.G. and Dreyfuss, G. (1994) Conserved structures and diversity of functions of RNA-binding proteins. Science, 265, 615-621.
4. Cooke, H.J., Lee, M., Kerr, S. et al. (1996) A murine homologue of the human DAZ gene is autosomal and expressed only in male and female gonads. Hum. Mol. Genet., 5, 513-516.
5. Eberhart, C.G., Maines, J.Z. and Wasserman, S.A. (1996) Meiotic cell cycle requirement for a fly homologue of human deleted in azoospermia. Nature, 381, 783-785.
6. Fulton, A.B., Wan, K.M. and Penman, S. (1980) The spatial distribution of polyribosomes in 3T3 cells and the associated assembly of proteins into the skeletal framework. Cell, 20, 849-857.
7. Hargreave, T.B. (1990) Introduction. In Hargreave, T.B. and Soom, I.E. (eds), Management of Male Infertility. PG Publishing, Singapore, pp. 1-21.
8. Hecht, N.B. (1995) The making of a spermatozoon: a molecular perspective. Dev, Genet., 16, 95-103.
9. Henkel, R., Stalf, T. and Miska, W. (1992) Isolation and partial characterization of the outer dense fiber proteins from human spermatozoa. Biol Chem. Hoppe-Seyler, 373, 685-389.
10. Kent-First, M.G., Kol, S., Mualiem, A. et al. (1996) The incidence and possible relevance of Y-linked microdeletions. Mol. Hum. Reprod., 2, 943-950.
11. Kumari, M., Aumüller, G., Hermann M. et al. (1990) Stage-dependent appearance of sulfhydryl oxidase during spermatogenesis in the testis of rat and hamster. Histochemistry, 94, 365-371.
12. Menke, D.B., Mutter, G.L. and Page, D.C. (1997) Expression of DAZ, an azoospermia factor candidate, in human spermatogenesis. Am. J. Hum. Genet., 60, 237-241.
13. Ord, T., Patrizio, P., Marello, E. et al. (1990) Mini-Percoll: a new method of semen preparation for IVF in severe male factor infertility. Hum. Reprod., 5, 987-989.
14. Pokrywka, N.J. and Stephenson, E.C. (1991) Microtubules mediate the localization of bicoid RNA during Drosophila oogenesis. Development, 113, 55-66.
15. Reijo, R., Lee, T.-Y, Salo P. et al. (1995) Diverse spermatogenic defects in humans caused by Y chromosome deletions encompassing a novel RNA-binding protein gene. Nature Genet., 10, 383-393.
16. Reijo, R., Alagappan, R.K., Patrizio, P. and Page D.C. (1996) Severe oligozoospermia resulting from deletions of azoospermia factor gene on Y chromosome. Lancet, 347, 1290-1293.
17. Ruggiu, M., Speed, R., Taggart, M. et al. (1997) The mouse Dazla gene encodes a cytoplasmic protein essential for sperm and egg production. Nature, 389, 73-76.
18. Saxena, R., Brown, L.G., Hawkins, T. et al. (1996) The DAZ gene cluster on the human Y chromosome arose from an autosomal gene that was transposed, repeatedly amplified and pruned. Nature Genet., 14, 292-299.
19. Schumacher, J.M., Keesook, L., Edelhoff, S. and Braun, R.E. (1995) Spnr, a murine RNA-binding protein that is localized to cytoplasmic microtubules. J. Cell Biol., 129, 1023-1032.
20. Seboun, E., Barbaux, S., Bourgeron, T. et al. (1997) Gene sequence, localization and evolutionary conservation of DAZLA, a candidate male sterility gene. Genomics, 41, 227-235.
21. Shan, Z., Hirschmann, P., Seebacher, T. et al. (1996) A SPGY copy homologous to the mouse gene Dazla and the Drosophila gene Boule is autosomal and expressed only in the human male gonad. Hum. Mol. Genet., 5, 2005-2011.
22. Vereb, M., Agulnik, A.I., Houston, J.T. et al. (1997) Absence of DAZ gene mutations in cases of non-obstructed azoospermia. Mol. Hum. Reprod., 3, 55-59.
23. Vogt, P.H., Edelmann, A., Kirsch S. et al. (1996) Human Y chromosome azoospermia factors (AZF) mapped to different subrogions in Yq11. Hum. Mol. Genet., 5, 933-943.
24. Vogt, PH., Affara, N., Davey, P. et al. (1997) Report of the third international workshop on Y chromosome mapping. Cytogenet. Cell Genet., 79, in press.
25. World Health Organization (1992) Laboratory Manual for the Examination of Human Semen and Semen-Cervical Mucus Interaction. 3rd edn. Cambridge University Press, Cambridge, UK, pp. 51-52.
26. Yen, PH., Chai, N.N. and Salido, B.C. (1996) The human autosomal gene DAZLA: testas specificity and a candidate for male infertility. Hum. Mol. Genet., 5, 2013-2017.
27. Yisraeli, J.K., Sokol, S. and Melton, D.A. (1990) A two-step model for the localization of maternal mRNA in Xenopus oocytes: involvement of microtubules and microfilaments in the translocation and anchoring of Vg1 mRNA. Development, 108, 289-298.