Y chromosome (Yq11) microdeletions in idiopathic azoospermia

International Journal of Urology

Volumn 4, Issue 2, 1997, Pages 198-201

  Shirakawa, Toshiro ^a   Fujisawa, Masato ^a   Kanzaki, Masanori ^a   Okada, Hiroshi ^a   Arakawa, Soichi ^a   Kamidono, Sadao ^a  

^a KOBE UNIVERSITY   (Japan)

Author keywords

Azoospermia; Microdeletion; Y chromosome

Indexed keywords

ADULT; ARTICLE; AZOOSPERMIA; CHROMOSOME YQ; CLINICAL ARTICLE; CYTOGENETICS; GENE DELETION; HUMAN; KARYOTYPE 46,XY; MALE; MALE INFERTILITY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SERTOLI CELL; SPERMATOGENESIS; SPERMATOZOON MATURATION; Y CHROMOSOME;

EID: 0030889573     PISSN: 09198172     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1442-2042.1997.tb00170.x     Document Type: Article

References (18)

1. Jaffe T, Oates RD. Genetic abnormalities and reproductive failure. Urol Clin North Am 1994;21:389-408.
2. Tiepolo L, Zuffardi O. Localization of factors controlling spermatogenesis in the nonfluorescent portion of the human Y chromosome long arm. Hum Genet 1976;34:119-124.
3. Sandberg A. The Y chromosome part B: clinical aspects of Y chromosome abnormalities (Progress and topics in cytogenetics, vol 6B), New York: Liss, 1985.
4. Fitch N, Richer C, Pinsky L, Kahn A. Deletion of the long arm of the Y chromosome abnormalities. Am J Med Genet 1985;20:31-42.
5. Anderson M, Page DC, Pettay D, Subrt I, Turleau C, de Grouchy J, de la Chapelle A. Y; autosome translocations and mosaicism in the aetiology of 45X maleness: assignment of fertility factor to distal Yq11. Hum Genet 1988;79:2-7.
6. Vogt P, Chandley AC, Hargreave TB, Keil R, Ma K, Sharkey A. Microdeletion in interval 6 of the Y chromosome of males with idiopathic sterility point to disruption of AZF, a human spermatogenesis gene. Hum Genet 1992;89:491-496.
7. Nagafuchi S, Namiki M, Nakahori Y, Kondo N, Okuyama A, Nakagome Y. A minute deletion of the Y chromosome in men with azoospermia. J Urol 1993;150:1155-1157.
8. Ma K, Sharkey A, Kirsch S, Vogt P, Keil R, Hargreave TB, McBeath S, Chandley AC. Towards the molecular localization of the AZF locus: mapping of microdeletions in azoospermic men within 14 subintervals of interval 6 of the human Y chromosome. Hum Mol Gen 1992;1:29-33.
9. Ma K, Inglis JD, Sharkey A, Bickmore WA, Hill RE, Prosser EJ, Speed RM, Thomson EJ, Jobling M, Taylor K, Wolfe J, Cooke JH, Hargreave TB, Chandley AC. A Y chromosome gene family with RNA-binding protein homology: candidates for the azoospermia factor AZF controlling human spermatogenesis. Cell 1993;75: 1287-1295.
10. Vogt P, Keil R, Kirsch S. The "AZF" function of the human Y chromosome during spermatogenesis. Chromosomes Today 1993;11:227-239.
11. Chandley AC, Cooke HJ. Human male fertility-Y-linked genes and spermatogenesis. Hum Mol Genet 1994;3:1449-1452.
12. Reijo R, Lee TY, Salo P, Alagappan R, Brown LG, Rosenberg M, Rozen S, Jaffe T, Straus D, Hovatta, Chapelle A, Silber S, Page DC. Diverse spermatogenic defects in humans caused by Y chromosome deletions encompassing a novel RNA-binding protein gene. Nature Genet 1995;10:383-393.
13. Henegariu O, Hirschmann P, Kilian K, Kirsch S, Lengauer C, Maiwald R, Mielke K, Vogt P. Rapid screening of the Y chromosome in idiopathic sterile men, diagnostic for deletions in AZF, a genetic Y factor expressed during spermatogenesis. Andrologia 1994; 26:97-106.
14. Vergnaud G, Page DC, Simmler MC, Brown L, Rouyer F, Noel B, Botstein D, de la Chapelle A, Weissenbach J. A deletion map of the human Y chromosome based on DNA hybridization. Am J Hum Genet 1986;38:109-124.
15. Johnson MD, Tho SPT, Behzadian A, Mcdonough PG. Molecular scanning of Yq11 (interval 6) in men with Sertoli-cell-only syndrome. Am J Obstet Gynecol 1989;161:1732-1737.
16. Kobayashi K, Mizuno K, Hida A, Komaki R, Tomita K, Matsushita I, Namiki M, Iwamoto T, Tamura S, Minowada S, Nakahori Y, Nakagome Y. PCR analysis of the Y chromosome long arm in azoospermic patients: evidence for a second locus required for spermatogenesis. Hum Mol Genet 1994;11:1965-1967.
17. Solomon E, Rawlings C. Human gene mapping 11: eleventh international workshop on human gene mapping. Cytogenet Cell Genet 1991;58:1-984.
18. Abbs S, Yau SC, Clark S, Mathew CG, Bobrow M. A convenient multiplex PCR system for the detection of dystrophin gene deletions: a comparative analysis with cDNA hybridization shows mistypings by both methods. J Med Genet 1991;28:304-311.