Long-term electrophysiological effects of regional cardiac sympathetic denervation of the neonatal dog

Cardiovascular Research

Volumn 51, Issue 4, 2001, Pages 659-669

  Sosunov, Eugene A ^a   Anyukhovsky, Evgeny P ^a   Gainullin, Ravil Z ^a   Plotnikov, Alexei ^a   Danilo Jr , Peter ^a   Rosen, Michael R ^a  

^a College of Physicians and Surgeons of Columbia University ^*  (United States)

Author keywords

Arrhythmia (mechanisms); Autonomic nervous system; ECG; Membrane potential; Purkinje fiber; Ventricular arrhythmias

Indexed keywords

ISOPRENALINE;

ADRENERGIC TRANSMISSION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASYSTOLE; CONTROLLED STUDY; DOG; DRUG EFFECT; ELECTROCARDIOGRAM; HEART DENERVATION; HEART DEPOLARIZATION; HEART ELECTROPHYSIOLOGY; HEART LEFT VENTRICLE; HEART MUSCLE; HEART SURGERY; HEART VENTRICLE SEPTUM; NERVE POTENTIAL; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PURKINJE FIBER; QT INTERVAL; SUDDEN DEATH; SYMPATHETIC NERVE; TACHYCARDIA;

ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; ARRHYTHMIA; BREEDING; DOGS; ELECTROCARDIOGRAPHY; ISOPROTERENOL; MEMBRANE POTENTIALS; PHENYLEPHRINE; PURKINJE FIBERS; STELLATE GANGLION; STIMULATION, CHEMICAL; SYMPATHECTOMY; SYMPATHOMIMETICS; TIME FACTORS;

EID: 0034877348     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(01)00333-9     Document Type: Article

References (35)

1. Role of the sympathetic nervous system in the genesis of ventricular arrhythmia
2. Effectiveness and limitations of beta-blocker therapy in congenital long-QT syndrome
3. Functional coupling of human β3-adrenoreceptors to the KvLQT1/MinK potassium channel
4. The long QT syndromes: Genetic basis and clinical implications
5. Long QT syndrome: Ionic basis and arrhythmia mechanism in long QT syndrome type 1
6. Sympathetic innervation modulates ventricular impulse propagation and repolarisation in the immature rat heart
7. + currents in rat epicardial myocytes
8. Inherited ventricular arrhythmias and sudden death in German shepherd dogs
9. An animal model of spontaneous arrhythmic death
10. Age dependence of the development of ventricular arrhythmias in canine model of sudden cardiac death
11. Triggered activity as a mechanism for inherited ventricular arrhythmias in German shepherd dogs
12. Abnormal cardiac repolarization and impulse initiation in German shepherd dogs with inherited ventricular arrhythmias and sudden death
13. Heterogeneous sympathetic innervation in German shepherd dogs with inherited ventricular arrhythmia and sudden cardiac death
14. Electrophysiologic characteristics of M cells in the canine left ventricular free wall
15. Regional differences in electrophysiologic properties of epicardium, midmyocardium, and endocardium: In vitro and in vivo correlations
16. 2-adrenergic receptor subtype effects in German shepherd dogs with inherited lethal ventricular arrhythmias
17. Mutations in the cardiac ryanodine receptor gene (hRyR2) underlie catecholaminergic polymorphic ventricular tachycardia
18. Ks channel: Coassembly of IsK (minK) and KvLQT1 proteins
19. Multiple mechanisms in the long-QT syndrome
20. Trophic influence of sympathetic neurons on the cardiac α-adrenergic response requires close nerve-muscle association
21. f) in rat ventricle
22. Alpha-adrenergic modulation of cardiac rhythm
23. Age-related appearance of outward currents may contribute to developmental differences in ventricular repolarization
24. to in left ventricular myocytes from German shepherd dogs with inherited arrhythmias
25. Transient outward potassium current and repolarization of cardiac cells
26. f, in rat ventricle cells
27. Mechanisms of supersensitivity to sympathomimetic amines in the chronically denervated heart of the conscious dog
28. Age-related differences in β-adrenergic regulation of repolarization in canine epicardial myocytes
29. Regulation of the cardiac delayed rectifier K current by neurotransmitters and magnesium
30. Calcium channel modulation by neurotransmitters, enzymes and drugs
31. Ks does not induce early afterdepolarization activity but promotes β-adrenergic agonist-induced delayed afterdepolarization activity
32. Differential effect of β-adrenergic stimulation on the frequency-dependent electrophysiologic actions of the new class III antiarrhythmics dofetilide, ambasilide, and chromanol 293B
33. Differential effects of β-adrenergic agonists and antagonists in LQT1, LQT2 and LQT3 models of the long QT syndrome
34. Ks defects