Vasomotor effects of L- and D-arginine in stenotic atheromatous coronary plaque

Heart

Volumn 86, Issue 3, 2001, Pages 296-301

  Tousoulis, D ^a   Davies, G J ^b   Tentolouris, C ^a   Goumas, G ^a   Stefanadis, C ^a   Toutouzas, P ^a   Crake, T ^b  

^a UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^b HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

Coronary artery disease; Endothelium; L arginine, vasomotor tone

Indexed keywords

ARGININE; DEXTRO ARGININE; GLYCEROL NITRATE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ADULT; ANGINA PECTORIS; ANGIOCARDIOGRAPHY; ARTICLE; ATHEROSCLEROTIC PLAQUE; CLINICAL ARTICLE; CORONARY ARTERY ATHEROSCLEROSIS; CORONARY ARTERY DISEASE; CORONARY ARTERY OBSTRUCTION; DISEASE SEVERITY; FEMALE; HUMAN; INTRACORONARY INFUSION; MALE; PRIORITY JOURNAL; STATISTICAL ANALYSIS; STEREOSPECIFICITY; VASCULAR ENDOTHELIUM; VASODILATATION;

EID: 0034876097     PISSN: 13556037     EISSN: None     Source Type: Journal    
DOI: 10.1136/heart.86.3.296     Document Type: Article

References (45)

1. Nitric oxide: Physiology pathology and pharmacology
2. The endothelium. Modulator of vascular smooth muscle tone
3. Endothelial control of vascular tone in large and small coronary arteries
4. Vascular endothelial cells synthesize nitric oxide from L-arginine
5. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor
6. A specific inhibitor of nitric oxide formation from L-arginine attenuates endothelium-dependent relaxation
7. L-arginine improves endothelium-dependent vasodilation in hypercholesterolemic humans
8. Effects of L-arginine on forearm vessels and responses to acetylcholine
9. Effects of dietary L-arginine on atherosclerosis and endothelium-dependent vasodilation in the hypercholesterolemic rabbit: Response according to treatment duration, anatomic site, and sex
10. Correction of endothelial dysfunction in coronary microcirculation of hypercholesterolemic patients by L-arginine
11. Effects of L-arginine supplementation on endothelium-dependent coronary vasodilation in patients with angina pectoris and normal coronary angiograms
12. L-arginine augments endothelium-dependent vasodilation in cholesterol-fed rabbits
13. L-arginine prevents xanthoma development and inhibits atherosclerosis in LDL receptor knockout mice
14. Anti-atherogenic effects of L-arginine in hypercholesterolemic rabbit
15. Coronary stenosis dilation induced by L-arginine
16. Does acute improvement of endothelial dysfunction in coronary artery disease improve myocardial ischemia? A double-blind comparison of parenteral D- and L-arginine
17. Complex stenosis morphology and vasomotor responses to inhibition of nitric oxide synthesis
18. Assessment of short-, medium, and long-term variations in arterial dimensions from computer-assisted quantitation of coronary cineangiograms
19. Coronary vasomotor effects of setotonin in patients with angina. Relationship to coronary stenosis morphology
20. Reactivity of eccentric and concentric stenoses in chronic stable angina
21. Coronary angiographic morphology in myocardial infarction: A link between the pathogenesis of unstable angina and myocardial infarction
22. Angiographic evolution of coronary artery morphology in unstable angina
23. Morphology of left anterior descending coronary territory lesions as a predictor of anterior myocardial infarction: A CASS registry study
24. Angiographic characteristics of the infarct and non-infarct related stenoses in patients with stable angina progressed to acute myocardial infarction
25. Macrophages and atherosclerosis plaque stability
26. Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques
27. Matrix metalloproteinases and cardiovascular disease
28. Evidence for increased collagenolysis by interstitial collagenases-1 and -3 in vulnerable human atheromatous plaques
29. Enhanced vasomotor responses of complex stenoses to acetylcholine in patients with chronic stable angina
30. Effects of inhibition of nitric oxide synthesis in patients with coronary artery disease and stable angina
31. Inducible NO synthase is present within human atherosclerotic lesions and promotes the formation and activity of peroxynitrite
32. Expression of inducible nitric oxide synthase in T lymphocytes and macrophages of cholesterol-fed rabbits
33. Regulation of matrix metalloproteinase expression in human vascular smooth muscle cells by T-lympocytes
34. Apoptosis in human acute myocardial infarction
35. Effect of L-arginine on acetylcholine-induced endothelium-dependent vasodilation differs between the coronary and forearm vasculatures in humans
36. Early endothelial dysfunction in adults and risk from atherosclerosis: Different responses to L-arginine
37. Arginine restores cholinergic relaxation of hypercholesterolemic rabbit thoracic aorta
38. Restoring vascular nitric oxide formation by L-arginine improves the symptoms of intermittent claudication in patients with peripheral arterial occlusive disease
39. Production of hydroxyl radicals from the simultaneous generation of superoxide and nitric oxide
40. L-arginine infusion decreases peripheral arterial resistance and inhibits platelet aggregation in healthy subjects
41. Dilator actions of arginine in human peripheral vasculature
42. Effect of L-arginine on human coronary endothelial-dependent and physiologic vasodilation
43. Effects of infusion of L-arginine into the left anterior descending coronary artery on acetylcholine-induced vasoconstriction of human atheromatous coronary arteries
44. Effect of increased availability of endothelium-derived nitric oxide precursor on endothelium-dependent vascular relaxation in normal subjects and in patients with essential hypertension
45. Oral L-arginine improves endothelium-dependent dilation in hypercholesterolemic young adults