Multipoint analysis using affected sib pairs: Incorporating linkage evidence from unlinked regions

Genetic Epidemiology

Volumn 21, Issue 2, 2001, Pages 105-122

  Liang, Kung Yee ^a   Chiu, Yen Feng ^b   Beaty, Terri H ^a   Wjst, Matthias ^c  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^b IL   (United States)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

Affected sib pairs; Complex disease; Generalized estimating equations; Identity by descent; Two locus models

Indexed keywords

ALLELE; ASTHMA; CHROMOSOME 20; CHROMOSOME 6; EVIDENCE BASED MEDICINE; GENE MAPPING; GENETIC ANALYSIS; GENETIC LINKAGE; GENETIC MARKER; GENETIC SUSCEPTIBILITY; HUMAN; MAJOR CLINICAL STUDY; MATHEMATICAL COMPUTING; REVIEW; SIBLING; STATISTICAL ANALYSIS;

ASTHMA; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 20; CHROMOSOMES, HUMAN, PAIR 6; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LINKAGE (GENETICS); MODELS, GENETIC; MODELS, STATISTICAL; NUCLEAR FAMILY;

EID: 0034873749     PISSN: 07410395     EISSN: None     Source Type: Journal    
DOI: 10.1002/gepi.1021     Document Type: Review

References (19)

1. Effects of misspecifying genetic parameters in lod score analysis
2. Two-locus maximum lod score analysis of the multifactorial trait: Joint consideration if IDDM2 and IDDM4 with IDDM1 in Type I diabetes
3. Loci on chromosome 2 (NIDDM1) and 15 interact to increase susceptibility to diabetes in Mexican Americans
4. Affected sibpair linkage tests for multiple linked susceptibility genes
5. A genome-wide search for human non-insulin-dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2
6. The investigation of linkage between a quantitative trait and a marker locus
7. Allele-sharing models: LOD scores and accurate linkage tests
8. Parametric and nonparametric linkage analysis: A unified multipoint approach
9. A genetical model for emergensis: In memory of Laurence H. Snyder 1901-86
10. Longitudinal data analysis using generalized linear models
11. A robust identity by descent procedure using affected sib pairs: Multipoint mapping for complex diseases
12. A unified sampling approach for multipoint analysis of qualitative and quantitative traits in sib pairs
13. Joint linkage of multiple loci for a complex disorder
14. Two-locus models of disease
15. Linkage strategies for genetically complex traits. I. Multilocus models
16. Linkage strategies for genetically complex traits. II. The power of affected relative pairs
17. Two-trait-locus linkage analysis: A powerful strategy for mapping complex genetic traits
18. A genome-wide search for linkage to asthma