Polymorphism and chromosomal localization of the GI-form of human glutathione peroxidase (GPX2) on 14q24.1 by in situ hybridization

Genomics

Volumn 32, Issue 2, 1996, Pages 272-276

  Chu, Fong Fong ^a,e   De Silva, H A Rohan ^b   Esworthy, R Steven ^a   Boteva, Kalina K ^c   Walters, Claire E ^c   Roses, Allen ^c   Rao, P Nagesh ^d   Pettenati, Mark J ^d  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^b MARIE CURIE RESEARCH INSTITUTE   (United Kingdom)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

^d WAKE FOREST SCHOOL OF MEDICINE   (United States)

^e NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTATHIONE PEROXIDASE; INTESTINE ENZYME;

ARTICLE; CAUCASIAN; CHROMOSOMAL LOCALIZATION; CHROMOSOME 14Q; DNA POLYMORPHISM; FLUORESCENCE IN SITU HYBRIDIZATION; GENE LOCATION; HUMAN; METAPHASE CHROMOSOME; NORMAL HUMAN; PRIORITY JOURNAL; SINGLE STRAND CONFORMATION POLYMORPHISM;

EID: 0029864627     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.1996.0115     Document Type: Article

References (11)

1. Cadenas, E. (1989). Biochemistry of oxygen toxicity. Annu. Rev. Biochem. 58: 79-110.
2. Chu, F.-F. (1994). The human glutathione peroxidase genes GPX2, GPX3, and GPX4 map to chromosomes 14, 5, and 19, respectively. Cytogenet. Cell Genet. 66: 96-98.
3. Chu, F.-F., Doroshow, J. H., and Esworthy, R. S. (1993). Expression, characterization, and tissue distribution of a new cellular selenium-dependent glutathione peroxidase, GSHPx-GI. J. Biol. Chem. 268: 2571-2576.
4. Cox, D. W. (1994). Report of the first international workshop on human chromosome 14 mapping 1993. Cytogenet Cell Genet. 66: 2-9.
5. Dausett, J., Cann, H., Cohen, D., Lathrop, M., Lalouel, J. M., and White, R. (1990). Centre d'etude du polymorphisme humain (CEPH): Collaborative genetic mapping of the human genome. Genomics 6: 575-577.
6. Freeman, B. A., and Crapo, J. D. (1982). Biology of disease: Free radicals and tissue injury. Lab. Invest. 47: 412-426.
7. Hirai, M., Suto, Y., and Kanoh, M. (1994). A method for simultaneous detection of fluorescent G-bands and in situ hybridization signals. Cytogenet. Cell Genet. 66: 149-151.
8. Orita, M., Iwahana, H., Kanazawa, H., Hayashi, K., and Sekiya, T. (1989). Detection of polymorphisms of human DNA by gel electrophoresis as single-stranded conformation polymorphisms. Proc. Natl. Acad. Sci. USA 86: 2766-2770.
9. Rotschild, C. R., Akots, G., Hayworth, R., Pettenati, M. J., Rao, P. N., Woods, P., Fajans, S. S., and Bowden, D. W. (1993). A genetic map of chromosome 20q12-q13.1: Multiple highly polymorphic microsatellite and RFLP markers linked to the maturity onset diabetes of the young (MODY) locus. Am. J. Hum. Genet. 52: 110-123.
10. St George-Hyslop, P. H., Haines, J., Rogaev, E., Mortilla, M., Vaula, G., Pericak-Vance, M., Foncin, J.-F., Montesi, M., Bruni, A., Sorbi, S., Rainero, I., Pinessi, L., Pollen, D., Polinsky, R., Nee, L., Kennedy, J., Macciardi, F., Rogaeva, E., Liang, Y., Alexandrova, N., Lukiw, W., Schlumpf, K., Tanzi, R., Tsuda, T., Farrer, L., Cantu, J.-M., Duara, R., Amaducci, L., Bergamini, L., Gusella, J., Roses, A., and Crapper McLachlan, D. (1992). Genetic evidence for a novel familial Alzheimer's disease locus on chromosome 14. Nature Genet. 2: 330-334.
11. Sherrington, R., Rogaev, E. I., Liang, Y., Rogaeva, E. A., Levesque, G., Ikeda, M., Chi, H., Lin, C., Li, G., Holman, K., Tsuda, T., Mar, L., Foncin, J.-F., Bruni, A. C., Montesi, M. P., Sorbi, S., Rainero, I., Pinessi, L., Nee, L., Chumakov, Y., Pollen, D., Brookes, A., Sanseau, P., Polinsky, R. J., Wasco, W., de Silva, H. A. R., Haines, J. L., Pericak-Vance, M. A., Tanzi, R. E., Roses, A. D., Fraser, P. E., Rommens, J., and St. George-Hyslop, P. H. (1995). Cloning of a gene bearing missense mutations in early-onset familial Alzheimer disease. Nature 375: 754-760.