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Volumn 36, Issue 8, 2001, Pages 889-901
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In vitro immunosuppressive activity of tacrolimus dihydrodiol precursors obtained by chemical oxidation and identification of a new metabolite of SDZ-RAD by electrospray and electrospray-linked scan mass spectrometry
a
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Author keywords
Drug metabolism; Immunosuppressive drugs; Mass spectrometry; SDZ RAD; Tacrolimus
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Indexed keywords
BIOLOGICAL ORGANS;
DRUG DOSAGE;
MASS SPECTROMETERS;
OXIDATION;
ELECTROSPRAY;
ORGANIC COMPOUNDS;
DRUG METABOLITE;
EPOXIDE;
EVEROLIMUS;
IMMUNOSUPPRESSIVE AGENT;
LACTONE;
MACROLIDE;
TACROLIMUS;
ANIMAL TISSUE;
ARTICLE;
CONTROLLED STUDY;
DRUG ACTIVITY;
DRUG IDENTIFICATION;
DRUG METABOLISM;
DRUG STRUCTURE;
FEMALE;
IN VITRO STUDY;
LIVER MICROSOME;
MASS SPECTROMETRY;
MIXED LYMPHOCYTE REACTION;
NONHUMAN;
OXIDATION;
PRIORITY JOURNAL;
SWINE;
ANIMALS;
BIOTRANSFORMATION;
CELLS, CULTURED;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
HUMANS;
IMMUNOSUPPRESSIVE AGENTS;
LACTONES;
LYMPHOCYTE CULTURE TEST, MIXED;
LYMPHOCYTES;
MICROSOMES, LIVER;
MODELS, MOLECULAR;
MOLECULAR CONFORMATION;
NADP;
OXIDATION-REDUCTION;
SIROLIMUS;
SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;
STEREOISOMERISM;
SWINE;
TACROLIMUS;
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EID: 0034853228
PISSN: 10765174
EISSN: None
Source Type: Journal
DOI: 10.1002/jms.190 Document Type: Article |
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Times cited : (9)
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References (27)
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