-
1
-
-
0016370945
-
Analytical study of microsomes and isolated subcellular membranes from rat liver
-
Amar-Costesec A, Beaufay A, Wibo M, Thines-Sempoux D, Feytimans E, Robbi M and Berthet J (1974) Analytical study of microsomes and isolated subcellular membranes from rat liver. J Cell Biol 61:201-212.
-
(1974)
J Cell Biol
, vol.61
, pp. 201-212
-
-
Amar-Costesec, A.1
Beaufay, A.2
Wibo, M.3
Thines-Sempoux, D.4
Feytimans, E.5
Robbi, M.6
Berthet, J.7
-
2
-
-
0028852791
-
Three-dimensional structure and actions of immunosuppressants and their immunophilins
-
Braun W, Kallen J, Mikol V, Walkinshaw MD and Wütherich K (1995) Three-dimensional structure and actions of immunosuppressants and their immunophilins. FASEB J 9:63-72.
-
(1995)
FASEB J
, vol.9
, pp. 63-72
-
-
Braun, W.1
Kallen, J.2
Mikol, V.3
Walkinshaw, M.D.4
Wütherich, K.5
-
3
-
-
0026343345
-
High performance liquid chromatography/mass spectrometry of FK-506 and its metabolites in blood, bile and urine of liver-grafted patients
-
Christians U, Braun F, Kosian N, Schmidt M, Schiebel M, Ernst L, Kruse C, Winkler M, Holze I, Linck A and Sewing KFr (1991) High performance liquid chromatography/mass spectrometry of FK-506 and its metabolites in blood, bile and urine of liver-grafted patients. Transplant Proc 23:2741-2744.
-
(1991)
Transplant Proc
, vol.23
, pp. 2741-2744
-
-
Christians, U.1
Braun, F.2
Kosian, N.3
Schmidt, M.4
Schiebel, M.5
Ernst, L.6
Kruse, C.7
Winkler, M.8
Holze, I.9
Linck, A.10
Sewing, K.Fr.11
-
4
-
-
0025831980
-
Two cytoplasmic candidates for immunophilin action are revealed by affinity for a new cyclophilin: One in the presence and one in the absence of CsA
-
Friedman J and Weissman I (1991) Two cytoplasmic candidates for immunophilin action are revealed by affinity for a new cyclophilin: One in the presence and one in the absence of CsA. Cell 66:799-806.
-
(1991)
Cell
, vol.66
, pp. 799-806
-
-
Friedman, J.1
Weissman, I.2
-
5
-
-
0024472603
-
A receptor for the immunosuppressant FK-506 is a cis-trans peptidyl-prolyl-isomerase
-
Harding WM, Galat A, Uehling DE and Speicher DW (1989) A receptor for the immunosuppressant FK-506 is a cis-trans peptidyl-prolyl-isomerase. Nature (Lond) 341:758-760.
-
(1989)
Nature (Lond)
, vol.341
, pp. 758-760
-
-
Harding, W.M.1
Galat, A.2
Uehling, D.E.3
Speicher, D.W.4
-
6
-
-
0009470340
-
Physico-chemical properties of (-)-(1 R, 9 S, 12 S, 13 R, 14 S, 17 R, 18 E, 21 S, 23 S, 24 R, 25 S, 27 R)-17-allyl-1, 14-dihydroxy-12-[(E)-2-[(1 R, 3 R, 4 R)-4-hydroxy-3-methoxycyclohexyl]-l-methylvinyl]-23, 25-dimethoxy-13, 19, 21, 27-tetramethyl-11, 28-dioxa-4-azatricyclo[22,3.1.0] octacos-18-ene-2, 3, 10, 16-tetrone hydrate (FK-506)
-
Hane K, Fujioka M, Namiki Y, Kitagawa T, Kihara N, Shimatani K and Yasuda T (1992) Physico-chemical properties of (-)-(1 R, 9 S, 12 S, 13 R, 14 S, 17 R, 18 E, 21 S, 23 S, 24 R, 25 S, 27 R)-17-allyl-1, 14-dihydroxy-12-[(E)-2-[(1 R, 3 R, 4 R)-4-hydroxy-3-methoxycyclohexyl]-l-methylvinyl]-23, 25-dimethoxy-13, 19, 21, 27-tetramethyl-11, 28-dioxa-4-azatricyclo[22,3.1.0] octacos-18-ene-2, 3, 10, 16-tetrone hydrate (FK-506). Iyakuhin Kenkyu 23:33-44.
-
(1992)
Iyakuhin Kenkyu
, vol.23
, pp. 33-44
-
-
Hane, K.1
Fujioka, M.2
Namiki, Y.3
Kitagawa, T.4
Kihara, N.5
Shimatani, K.6
Yasuda, T.7
-
7
-
-
0028893714
-
Further metabolism of FK506 (Tacrolimus): Identification and biological activities of the metabolites oxidized at multiple sites of FK-506
-
Iwasaki K, Shiraga T, Matsuda H, Nagase K, Tokuda Y, Hata T, Fugii Y, Sakuma S, Fujitsu T, Fujikawa A, Shimatani K, Sato A and Fujioka M (1995) Further metabolism of FK506 (Tacrolimus): Identification and biological activities of the metabolites oxidized at multiple sites of FK-506. Drug Metab Disp 23:28-34.
-
(1995)
Drug Metab Disp
, vol.23
, pp. 28-34
-
-
Iwasaki, K.1
Shiraga, T.2
Matsuda, H.3
Nagase, K.4
Tokuda, Y.5
Hata, T.6
Fugii, Y.7
Sakuma, S.8
Fujitsu, T.9
Fujikawa, A.10
Shimatani, K.11
Sato, A.12
Fujioka, M.13
-
8
-
-
0027518214
-
Isolation, identification and biological activities of oxidative metabolites of FK506, a potent immunosuppressive macrolide lactone
-
Iwasaki K, Shiraga T, Nagase K, Tozuka Z, Noda S, Sakuma S, Fujitsu T, Shimatani K, Sato A and Fujioka M (1993) Isolation, identification and biological activities of oxidative metabolites of FK506, a potent immunosuppressive macrolide lactone. Drug Metab Disp 21:971-977.
-
(1993)
Drug Metab Disp
, vol.21
, pp. 971-977
-
-
Iwasaki, K.1
Shiraga, T.2
Nagase, K.3
Tozuka, Z.4
Noda, S.5
Sakuma, S.6
Fujitsu, T.7
Shimatani, K.8
Sato, A.9
Fujioka, M.10
-
9
-
-
0026721092
-
Rapamycin selectively inhibits interleukin-2 activation of 170 S6 kinase
-
Kuo CJ, Chung J, Florentino DF, Flanagan WM, Blenis J and Crabtree GR ( 1992) Rapamycin selectively inhibits interleukin-2 activation of 170 S6 kinase. Naturt (Lond) 358:70-73.
-
(1992)
Naturt (Lond)
, vol.358
, pp. 70-73
-
-
Kuo, C.J.1
Chung, J.2
Florentino, D.F.3
Flanagan, W.M.4
Blenis, J.5
Crabtree, G.R.6
-
10
-
-
0025869741
-
Complete amino acid sequence of the FK-506 and rapamycin binding protein, FKBP, isolated from calf thymus
-
Lane WS, Galat A, Harding MW and Schreiber SL (1991) Complete amino acid sequence of the FK-506 and rapamycin binding protein, FKBP, isolated from calf thymus. J Protein Chem 10:151-160.
-
(1991)
J Protein Chem
, vol.10
, pp. 151-160
-
-
Lane, W.S.1
Galat, A.2
Harding, M.W.3
Schreiber, S.L.4
-
13
-
-
0025893168
-
Calcineurin is a common target of cyclosporin-cyclosporin A and FFKBP-FK506 complexes
-
Liu, J Farmer JD, Lane WS, Friedman J, Weismann I and Schreiber SL (1991) Calcineurin is a common target of cyclosporin-cyclosporin A and FFKBP-FK506 complexes. Cell 66:807-815.
-
(1991)
Cell
, vol.66
, pp. 807-815
-
-
Liu, J.1
Farmer, J.D.2
Lane, W.S.3
Friedman, J.4
Weismann, I.5
Schreiber, S.L.6
-
15
-
-
0028598601
-
Modes of action of FK-506, cyclosporin A, and rapamycin
-
Morris R (1994) Modes of action of FK-506, cyclosporin A, and rapamycin. Transplant Proc 26:3272-3275.
-
(1994)
Transplant Proc
, vol.26
, pp. 3272-3275
-
-
Morris, R.1
-
16
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
-
Mosmann T (1983) Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immunol Meth 65:55-63.
-
(1983)
J Immunol Meth
, vol.65
, pp. 55-63
-
-
Mosmann, T.1
-
17
-
-
0025297483
-
Towards an optimized MTT assay
-
Nike M and Otto M (1990) Towards an optimized MTT assay. J Immunol Meth 130:149-151.
-
(1990)
J Immunol Meth
, vol.130
, pp. 149-151
-
-
Nike, M.1
Otto, M.2
-
18
-
-
78651165715
-
The carbon monoxide-binding pigment of liver microsomes. 1. Evidence for its hemoprotein nature
-
Omura T and Sato R (1964) The carbon monoxide-binding pigment of liver microsomes. 1. Evidence for its hemoprotein nature. J Biol Chem 239:2370-2378.
-
(1964)
J Biol Chem
, vol.239
, pp. 2370-2378
-
-
Omura, T.1
Sato, R.2
-
19
-
-
0026662551
-
Cytochrome P-450 3A enzymes are responsible for biotransformation of FK506 and rapamycin in man and rat
-
Sattler M, Guengerich FP, Yun CH, Christians U and Sewing KF (1992) Cytochrome P-450 3A enzymes are responsible for biotransformation of FK506 and rapamycin in man and rat. Drug Metab and Disp 20:753-761.
-
(1992)
Drug Metab and Disp
, vol.20
, pp. 753-761
-
-
Sattler, M.1
Guengerich, F.P.2
Yun, C.H.3
Christians, U.4
Sewing, K.F.5
-
20
-
-
0024959573
-
The nina A gene required for visual transduction in Drosophila encodes a homologue of cyclosporin A-binding protein
-
Shieh BH, Stamnes MA, Seavelb S, Harris GL and Zuker CS (1989) The nina A gene required for visual transduction in Drosophila encodes a homologue of cyclosporin A-binding protein. Nature (Land) 338:67-70.
-
(1989)
Nature (Land)
, vol.338
, pp. 67-70
-
-
Shieh, B.H.1
Stamnes, M.A.2
Seavelb, S.3
Harris, G.L.4
Zuker, C.S.5
-
21
-
-
0024442393
-
A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin
-
Siekirka JJ, Hung SHY, Poe M, Lin CS and Sigal NH (1989) A cytosolic binding protein for the immunosuppressant FK506 has peptidyl-prolyl isomerase activity but is distinct from cyclophilin. Nature 341:755-757.
-
(1989)
Nature
, vol.341
, pp. 755-757
-
-
Siekirka, J.J.1
Hung, S.H.Y.2
Poe, M.3
Lin, C.S.4
Sigal, N.H.5
-
22
-
-
0025061678
-
Molecular cloning and overexpression of the human FK-506- binding protein, FKBP
-
Standaert RF, Galat A, Verdine GL and Schreiber SL (1990) Molecular cloning and overexpression of the human FK-506-binding protein, FKBP. Nature (Lond) 346:671-674.
-
(1990)
Nature (Lond)
, vol.346
, pp. 671-674
-
-
Standaert, R.F.1
Galat, A.2
Verdine, G.L.3
Schreiber, S.L.4
-
23
-
-
0017129935
-
A sensitive micromethod for generating and assaying allogenically induced cytotoxic human lymphocytes
-
Zarling JM, Mc Keough M and Bach FH (1976) A sensitive micromethod for generating and assaying allogenically induced cytotoxic human lymphocytes. Trans-plantation 21:468-476.
-
(1976)
Trans-plantation
, vol.21
, pp. 468-476
-
-
Zarling, J.M.1
Mc Keough, M.2
Bach, F.H.3
|