Isolation from pig liver microsomes, identification by tandem mass spectrometry and in vitro immunosuppressive activity of an SDZ-RAD 17,18,19,20,21,22-tris-epoxide

Journal of Mass Spectrometry

Volumn 35, Issue 3, 2000, Pages 454-460

  Lhoest G J J ^a   Gougnard, T Y R ^b   Verbeeck, R K ^a   Maton, N ^a   Dehoux, J P ^a   Wallemacq, P ^c   Schuler W ^d   Latinne, D ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b UNIVERSITY OF LIÈGE   (Belgium)

^c CLINIQUES UNIVERSITAIRES SAINT LUC   (Belgium)

^d NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Drug metabolism; High performance liquid chromatography; Immunosuppressive activity; Immunosuppressive drugs; Mass spectrometry; SDZ RAD tris epoxide

Indexed keywords

BINDING PROTEIN; CYTOCHROME P450 3A4; EVEROLIMUS; IMMUNOSUPPRESSIVE AGENT; MACROLIDE; PHOSPHOTRANSFERASE; RAPAMYCIN; RECEPTOR; TACROLIMUS;

ARTICLE; DEMETHYLATION; DRUG HYDROXYLATION; DRUG METABOLISM; ENZYME INHIBITION; IMMUNOSUPPRESSIVE TREATMENT; LIVER MICROSOME; MIXED LYMPHOCYTE REACTION; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SWINE; TANDEM MASS SPECTROMETRY;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; EPOXY COMPOUNDS; FEMALE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; LYMPHOCYTE CULTURE TEST, MIXED; MASS SPECTROMETRY; MICROSOMES, LIVER; SIROLIMUS; SWINE;

SUS SCROFA;

EID: 0343775809     PISSN: 10765174     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9888(200003)35:3<454::AID-JMS959>3.0.CO;2-K     Document Type: Article

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