Comparison of quercetin and a non-orthohydroxy flavonol as antioxidants by competing in vitro oxidation reactions

Journal of Agricultural and Food Chemistry

Volumn 49, Issue 7, 2001, Pages 3370-3377

  Makris, Dimitris P ^a   Rossiter, John T ^b  

^a MEDITERRANEAN AGRONOMIC INSTITUTE OF CHANIA   (Greece)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

resorcylic acid; Antioxidant activity; Flavonols; Morin; Phenolic acids; Phloroglucinol carboxylic acid; Protocatechuic acid; Quercetin

Indexed keywords

ANTIOXIDANT; BETA CAROTENE; BETA RESORCYLIC ACID; DNA; FLAVONOL DERIVATIVE; LIPID; MORIN; PHLOROGLUCINOLCARBOXYLIC ACID; PROTEIN; PROTOCATECHUIC ACID; QUERCETIN;

ANTIOXIDANT ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA METABOLISM; DRUG POTENCY; DRUG STRUCTURE; IN VITRO STUDY; LIPID OXIDATION; OXIDATION; PROTEIN METABOLISM; STRUCTURE ACTIVITY RELATION;

ANTIOXIDANTS; FLAVONOIDS; FLAVONOLS; KINETICS; OXIDATION-REDUCTION; OXIDATIVE STRESS; QUERCETIN;

EID: 0034852948     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf010107l     Document Type: Article

References (10)

1. Makris, D. P.; Rossiter, J. T. High-performance liquid chromatography studies on free-radical oxidation of flavonols. Spec. Publ. - Royal Soc. Chem. 2000, 255, 249-251.
2. Makris, D. P.; Rossiter, J. T. Quercetin and rutin (quercetin 3-O-rhamnosylglucoside) thermal degradation in aqueous media under alkaline conditions. In Functional Foods II - Claims and Evidence; Buttriss J., Saltmarsh, M., Eds.; Royal Society of Chemistry Press: London, 2000; pp 216-238.
3. Makris, D. P.; Rossiter, J. T. Heat-induced, metal-catalyzed oxidative degradation of quercetin and rutin (quercetin 3-O-rhamnosylglucoside) in aqueous model systems. J. Agric. Food Chem. 2000, 48 (9), 3830-3838.
4. Fahey, J. W.; Clevidence, B. A.; Russell, R. M. Methods for assessing the biological effects of specific plant components. Nutr. Rev. 1999, 57 (9), S34-S40.
5. Igile, G. O.; Oleszek, W.; Jurzysta, M.; Burda, S.; Fafunso, M.; Fasanmade, A. A. Flavonoids from Vernonia amygdalina and their antioxidant activities. J. Agric. Food Chem. 1994, 42, 2445-2448.
6. Velioglou, Y. S.; Mazza, G.; Gao, L.; Oomah, B. D. Antioxidant activity and total phenolics in selected fruits, vegetables, and grain products. J. Agric. Food Chem. 1998, 46, 4113-4117.
7. Al-Saikhan, M. S.; Howard, L. R.; Miller, J. C., Jr. Antioxidant activity and total phenolics in different genotypes of potato (Solanum tuberosum, L.). J. Food Sci. 1995, 60 (2), 341-343.
8. Marinova, E. M.; Yanishlieva, N. V.; Kostova, I. N. Antioxidative action of the ethanolic extract and some hydroxycoumarins of Fraxinus ornus bark. Food Chem. 1994, 51, 125-132.
9. Afanas'ev, I. B.; Dorozhko, A. I.; Brodskii, A. V.; Kostyuk, V. A.; Potapovitch, A. I. Chelating and free radical scavenging mechanisms of inhibitory action of rutin and quercetin in lipid peroxidation. Biochem. Pharmacol. 1989, 38 (11), 1763-1769.
10. Fucci, L.; Oliver, C. N.; Coon, M. J.; Stadtman, E. R. Inactivation of key metabolic enzymes by mixed-function oxidation reactions: Possible implication in protein turnover and aging. Proc. Natl. Acad. Sci. U.S.A. 1983, 80, 1521-1525.