Preimplantation genetic diagnosis (PGD): Current status of research and clinical applications

Middle East Fertility Society Journal

Volumn 6, Issue 2, 2001, Pages 89-98

  Gitlin, S A ^a   Gibbons, W E ^a  

^a EASTERN VIRGINIA MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANEUPLOIDY; CHROMOSOME REARRANGEMENT; DIAGNOSTIC ERROR; FEMALE INFERTILITY; FERTILIZATION IN VITRO; FLUORESCENCE IN SITU HYBRIDIZATION; GENETIC SCREENING; POLYMERASE CHAIN REACTION; PREGNANCY; PRENATAL DIAGNOSIS; REVIEW; SPONTANEOUS ABORTION;

EID: 0034843912     PISSN: 11105690     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (73)

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3. Birth of a normal girl after in vitro fertilization and preimplantation diagnostic testing for cystic fibrosis
4. Molecular analysis of human platelet antigen system 1 antigen on single cells can be applied to preimplantation genetic diagnosis for prevention of alloimmune thrombocytopenia
5. Preimplantation diagnosis of genetic and chromosomal disorders
6. Pregnancy after preimplantation genetic diagnosis for Charcot-Marie-Tooth disease type 1A
7. Diagnosis of major chromosome aneuploidies in human preimplantation embryos
8. First pregnancies after preconception diagnosis of translocations of maternal origin
9. Preimplantation genetic diagnosis of DiGeorge syndrome
10. Normal pregnancy after preimplantation DNA diagnosis of a dystrophin gene deletion
11. Preimplantation genetic diagnosis in two families at risk for recurrence of Herlitz junctional epidermolysis bullosa
12. Preimplantation genetic diagnosis of inherited cancer: Familial adenomatous polyposis coli
13. Preimplantation diagnosis for fragile X syndrome based on the detection of the non-expanded paternal and maternal CGG
14. Preimplantation diagnosis for Huntington's disease (HD): Clinical application and analysis of the HD expansion in affected embryos
15. A pregnancy following PGD for X-linked autosomal dominant Incontinentia Pigmenti (Bloch-Sulzberger syndrome): Case Report
16. Preimplantation genetic diagnosis of human embryos for Marfan's syndrome
17. A successful strategy for preimplantation diagnosis of medium chain acyl-CoA dehydrogenase (MCAD) deficiency
18. Clinical application of preimplantation diagnosis for myotonic dystrophy
19. Two pregnancies after preimplantation genetic diagnosis for osteogenesis imperfecta type I and type IV
20. Single-cell analysis of the RhD blood type for use in preimplantation diagnosis in the prevention of severe hemolytic disease of the newborn
21. First unaffected pregnancy using preimplantation genetic diagnosis for sickle cell anemia
22. Preimplantation genetic diagnosis of spinal muscular atrophy
23. Preimplantation diagnosis of thalassemias
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33. Use of zona drilling for safe and effective biopsy of murine oocytes and embryos
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40. Gender determination by multiplex PCR amplification of alphoid repeat sequences from single cells
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42. DNA-based X-enriched sperm separation as an adjunct to preimplantation genetic testing for the prevention of X-linked disease
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47. Increasing the denaturation temperature during the first cycles of amplification reduces allele dropout from single cells for preimplantation genetic diagnosis
48. Multiple genetic diagnoses from single cells using multiplex PCR: Reliability and allele dropout
49. Fluorescent in-situ hybridization to interphase nuclei of human preimplantation embryos with X and Y chromosome specific probes
50. Cytogenetic and molecular analysis of sex-chromosome monosomy
51. Preimplantation diagnosis of the aneuploidies most commonly found in spontaneous abortions and live births: XY, 13, 14, 15, 16, 18, 21, 22
52. Assessment of numeric abnormalities of X, Y, 18, and 16 chromosomes in preimplantation human embryos before transfer
53. Infertile couples with Robertsonian translocations: Preimplantation genetic analysis of embryos reveals chaotic cleavage divisions
54. Molecular cloning of translocation breakpoints in a case of constitutional translocation t(11;22)(q23;q11) and preparation of probes for preimplantation genetic diagnosis
55. Preimplantation genetic diagnosis of a reciprocal translocation t(3;11) (q27.3;q24.3) in siblings
56. Clinical pregnancy following blastomere biopsy and PGD for a reciprocal translocation carrier: Analysis of meiotic outcomes and embryo quality in two IVF cycles
57. Chromosome translocations: Segregation modes and strategies for preimplantation genetic diagnosis
58. Optimal preparation of preimplantation embryo interphase nuclei for analysis by fluorescence in-situ hybridization
59. Improving the fixation method for preimplantation genetic diagnosis by fluorescent in situ hybridization
60. Clinical experience with preimplantation diagnosis of sex by dual fluorescent in situ hybridization
61. Reduction in signal overlap results in increased FISH efficiency: Implications for preimplantation genetic diagnosis
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63. Neonatal outcome of preimplantation genetic diagnosis by polar body removal: The first 109 infants
64. Recycling the single cell to detect specific chromosomes and to investigate specific gene sequences
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67. Preimplantation single-cell analysis of multiple genetic loci by whole-genome amplification
68. Comparative genomic hybridization: An overview
69. Detailed chromosomal and molecular genetic analysis of single cells by whole genome amplification and comparative genomic hybridization
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72. Evaluation of cytogenetic analysis for clinical preimplantation diagnosis
73. Rapid visualization of metaphase chromosomes in single human blastomeres after fusion with in-vitro matured bovine eggs