Practical synthesis of quinoline nucleus of NK-104

Heterocycles

Volumn 50, Issue 1, 1999, Pages 479-483

  Suzuki, Mikio ^a   Tanikawa, Keizo ^a   Sakoda, Ryozo ^a  

^a NISSAN CHEMICAL INDUSTRIES LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2 CYCLOPROPYL 4 (4' FLUOROPHENYL)QUINOLINE 3 CARBOXYLIC ACID ETHYL ESTER; 7 [2 CYCLOPROPYL 4 (4 FLUOROPHENYL) 3 QUINOLYL] 3,5 DIHYDROXY 6 HEPTENOIC ACID; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL REACTION; CRYSTALLIZATION; DRUG STRUCTURE; DRUG SYNTHESIS; POLYMERIZATION; REACTION ANALYSIS;

EID: 0032816231     PISSN: 03855414     EISSN: None     Source Type: Journal    
DOI: 10.3987/com-98-s(h)32     Document Type: Article

References (14)

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2. V. W. Rodwell, J. L. Nordstrom, and J. J. Mitschell, Adv. Lipid Res., 1976, 14, 1; M. S. Brown and J. L. Goldstein, Sci. Am., 1984, 52; A. Endo, M. Kuroda, and K. Tanzawa, FEBS Lett., 1976, 72, 323.
3. V. W. Rodwell, J. L. Nordstrom, and J. J. Mitschell, Adv. Lipid Res., 1976, 14, 1; M. S. Brown and J. L. Goldstein, Sci. Am., 1984, 52; A. Endo, M. Kuroda, and K. Tanzawa, FEBS Lett., 1976, 72, 323.
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8. See the review of Friedlander Synthesis; C.-C. Cheng and S.-J. Van, 'Organic Reactions , The Friedlander Synthesis of Quinolines', Vol. 28, ed. by W. G. Dauben, John Wiley & Sons, New York, 1982, p. 37; See Fehnel procedure; E. A. Fehnel, J. Heterocycl. Chem., 1967, 4, 565.
9. See the review of Friedlander Synthesis; C.-C. Cheng and S.-J. Van, 'Organic Reactions , The Friedlander Synthesis of Quinolines', Vol. 28, ed. by W. G. Dauben, John Wiley & Sons, New York, 1982, p. 37; See Fehnel procedure; E. A. Fehnel, J. Heterocycl. Chem., 1967, 4, 565.
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14. The methanesulfonate salt of 3 also can be used as the starting material.