Random sampling or 'random' model in skin flux measurements? [Commentary on 'Investigation of the mechanism of flux across human skin in vitro by quantitative structure-permeability relationships']

European Journal of Pharmaceutical Sciences

Volumn 14, Issue 3, 2001, Pages 197-200

  Poda, Gennadiy I ^a   Landsittel, Douglas P ^a   Brumbaugh, Kurt ^a   Sharp, Dan S ^a   Frasch, H Frederick ^a   Demchuk, Eugene ^a  

^a NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

Author keywords

Chemical diversity; Human skin; Quantitative structure activity relationships; Quantitative structure permeability relationships; Transdermal drug delivery

Indexed keywords

OCCUPATIONAL DISEASES; SKIN; STATISTICAL METHODS;

TRANSDERMAL THERAPY;

DRUG THERAPY;

DRUG;

ALGORITHM; ARTICLE; MODEL; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SKIN PERMEABILITY; STATISTICS; TRANSDERMAL DRUG ADMINISTRATION;

CELL MEMBRANE PERMEABILITY; DRUG CARRIERS; HUMANS; MODELS, STATISTICAL; PERMEABILITY; SKIN ABSORPTION; SKIN PHYSIOLOGY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0034835422     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0928-0987(01)00184-1     Document Type: Note

References (11)

1. Algorithms for skin permeability using hydrogen bond descriptors: the problem of steroids
2. Quantitative structure-activity relationships for skin permeability
3. Investigation of the mechanism of flux across human skin in vitro by quantitative structure-permeability relationships
4. Physicochemical determinants of skin absorption
5. The prediction of skin permeability by using physicochemical data
6. Predicting skin permeability
7. Prediction: simple risk models and overview of dermal risk assessment
8. Permeability of the skin
9. Estimating skin permeability of organic chemicals from aqueous solutions
10. Estimating skin permeation. The validation of five mathematical skin permeation models