P-glycoprotein preferentially effluxes anthracyclines containing basic versus charged amine

European Journal of Biochemistry

Volumn 268, Issue 6, 2001, Pages 1561-1567

  Frézard, Frédéric ^a,b   Pereira Maia, Elene ^a,b   Quidu, Patricia ^a   Priebe, Waldemar ^c   Garnier Suillerot, Arlette ^a  

^a UNIVERSITÉ PARIS 13   (France)

^b FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^c UNIVERSITY OF TEXAS   (United States)

Author keywords

Daunorubicin; Membrane transport; Multidrug resistance; P glycoprotein

Indexed keywords

AMINE; ANTHRACYCLINE; DAUNORUBICIN; DOXORUBICIN DERIVATIVE; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN; PROTON PUMP; WP 154; WP 401; WP 608; WP 656; WP 697;

ARTICLE; CELL LINE; CONTROLLED STUDY; DRUG ACCUMULATION; EFFUSION; HUMAN; HUMAN CELL; LIPOPHILICITY; MEMBRANE TRANSPORT; MOLECULAR DYNAMICS; MOLECULAR RECOGNITION; MULTIDRUG RESISTANCE; PH; PRIORITY JOURNAL; PROTEIN DETERMINATION; PUMP; SPECTROFLUOROMETRY;

AMINES; ANTIBIOTICS, ANTINEOPLASTIC; BIOLOGICAL TRANSPORT; DAUNORUBICIN; DRUG RESISTANCE, MULTIPLE; HUMANS; HYDROGEN-ION CONCENTRATION; K562 CELLS; KINETICS; P-GLYCOPROTEIN;

EID: 0034832521     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.2001.01989.x     Document Type: Article

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